CAS 1847-24-1

Flucloxacilina sódica

Descrição:

Flucloxacilina sódica é um antibiótico semissintético pertencente à classe das penicilinas, utilizado principalmente para tratar infecções causadas por bactérias Gram-positivas, particularmente Staphylococcus aureus. É caracterizado por sua estrutura beta-lactâmica, que é essencial para sua atividade antibacteriana. A forma de sal sódico melhora sua solubilidade em água, facilitando a administração intravenosa. A flucloxacilina é resistente à penicilinase, uma enzima produzida por certas bactérias que pode inativar outras penicilinas, tornando-a eficaz contra cepas resistentes à penicilina. É tipicamente administrada para infecções de pele, infecções do trato respiratório e infecções ósseas. O medicamento é bem absorvido quando tomado por via oral, embora sua biodisponibilidade possa ser afetada pela comida. Efeitos colaterais comuns podem incluir distúrbios gastrointestinais, reações alérgicas e, em casos raros, toxicidade hepática. Flucloxacilina sódica é geralmente contraindicado em indivíduos com alergia conhecida a penicilinas ou cefalosporinas. Assim como com todos os antibióticos, é crucial completar o curso prescrito para prevenir o desenvolvimento de resistência aos antibióticos.

Fórmula: C₁₉H₁₇ClFN₃O₅S·Na

InChI: InChI=1S/C19H17ClFN3O5S.Na/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);/t13-,14+,17-;/m1./s1

Chave InChI: InChIKey=PWDULVAXRLDWLM-SLINCCQESA-N

SMILES: C(O)(=O)[C@@H]1N2[C@@]([C@H](NC(=O)C=3C(=NOC3C)C4=C(Cl)C=CC=C4F)C2=O)(SC1(C)C)[H].[Na]

Sinónimos:

• (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-
• 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, (2S-(2-alpha,5-alpha,6-beta))-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-, sodium salt
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-(2α,5α,6β)]-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:1), (2S,5R,6R)-
• 5-Methyl-3-(2-chloro-6-fluorophenyl)-4-isoxazolylpenicillin sodium
• 6-({[3-(2-Chloro-6-Fluorophenyl)-5-Methyl-1,2-Oxazol-4-Yl]Carbonyl}Amino)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid
• Floxacillin Na salt
• Floxacillin sodium
• Floxapen
• Floxapen sodium
• Fluclox
• Flucloxacillin sodium salt
• Mfi-Pc
• Monosodium flucloxacillin
• Nsc 277175
• Sodium (2S-(2alpha,5alpha,6beta))-6-(((3-(2-chloro-6-fluorophenyl)-5-methylisoxazol-4-yl)carbonyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate
• Sodium 6-({[3-(2-Chloro-6-Fluorophenyl)-5-Methylisoxazol-4-Yl]Carbonyl}Amino)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
• Sodium [3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]penicillin
• Sodium flucloxacillin
• Stafopen sodium salt
• Staphylex
• Staphylex Sodium salt
• sodium (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Flucloxacillin sodium

CAS: 1847-24-1

Flucloxacillin sodium

Fórmula: C₁₉H₁₆ClFN₃NaO₅S

Peso molecular: 475.85

Ref: 02-J66615

FLUCLOXACILLIN SODIUM CRS

CAS: 1847-24-1

FLUCLOXACILLIN SODIUM CRS

Fórmula: C₁₉H₁₆ClFN₃NaO₅S

Cor e Forma: Crystalline Powder. White. Powder.

Peso molecular: 475.8536

Ref: 41-F0150000

Flucloxacillin sodium

CAS: 1847-24-1

Flucloxacillin sodium

Fórmula: C₁₉H₁₆ClFN₃NaO₅S

Pureza: 94.6%

Cor e Forma: Off-White

Peso molecular: 475.03809

Ref: 47-158

FLUCLOXACILLIN SODIUM RS

CAS: 1847-24-1

FLUCLOXACILLIN SODIUM RS

Fórmula: C₁₉H₁₆ClFN₃NaO₅S

Peso molecular: 475.8536

Ref: 41-ICRS0309

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-

CAS: 1847-24-1

Fórmula: C₁₉H₁₆ClFN₃NaO₅S

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 475.8536

Ref: IN-DA00IMLQ

Flucloxacillin Sodium Salt

CAS: 1847-24-1

Fórmula: C₁₉H₁₆ClFN₃O₅S·Na

Peso molecular: 452.86 22.99

Ref: 4Z-F-511

(2S,5R,6R)-6-(3-(2-Chloro-6-Fluorophenyl)-5-Methylisoxazole-4-Carboxamido)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid,Sodium Salt

CAS: 1847-24-1

(2S,5R,6R)-6-(3-(2-Chloro-6-Fluorophenyl)-5-Methylisoxazole-4-Carboxamido)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid,Sodium Salt

Pureza: 95%

Peso molecular: 475.85g/mol

Ref: 54-PC109118

Flucloxacillin sodium

CAS: 1847-24-1

Flucloxacillin sodium

Pureza: ≥95%

Peso molecular: 475.85g/mol

Ref: 54-BUP18366

Flucloxacillin Sodium

CAS: 1847-24-1

Fórmula: C₁₉H₁₆ClFN₃NaO₅S

Pureza: >95.0%(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 475.85

Ref: 3B-F1372

Flucloxacillin sodium

Produto Controlado

CAS: 1847-24-1

Fórmula: C₁₉H₁₆ClFN₃O₅S·Na

Cor e Forma: Neat

Peso molecular: 475.85

Ref: 04-C13696000

Flucloxacillin Sodium Hydrate

Produto Controlado

CAS: 1847-24-1, 34214-51-2

Cor e Forma: Neat

Ref: 86-MM0489.00

Flucloxacillin sodium

CAS: 1847-24-1

Flucloxacillin sodium (floxacillin sodium) is a highly active antibiotic against Gram-negative and Gram-positive bacteria.

Fórmula: C₁₉H₁₆ClFN₃NaO₅S

Pureza: 95.29% - 97.05%

Cor e Forma: White Solid

Peso molecular: 475.85

Ref: TM-T5006

Flucloxacillin sodium salt

CAS: 1847-24-1

Fórmula: C₁₉H₁₆ClFN₃O₅S·Na

Pureza: ≥ 95.0%

Cor e Forma: White to off-white crystalline powder

Peso molecular: 475.85

Ref: 7W-GA1968

Flucloxacillin-13C4 Sodium

Produto Controlado

CAS: 1847-24-1

Applications Labelled analogue of Flucloxacillin, a semisynthetic penicillin.
References Markovich, M. et al.: Antibiot. Med. Biotekhnol., 31, 603 (1986); Rahman, M. et al.: Biochem. Pharmacol., 46, 1721 (1993); Silva, D. et al.: Med. Biol. Res., 37, 963 (2004);

Fórmula: C₁₅₁₃C₄H₁₆ClFN₃NaO₅S

Cor e Forma: White To Off-White

Peso molecular: 479.82

Ref: TR-F419202

Flucloxacillin Sodium

CAS: 1847-24-1

Applications Flucloxacillin, a new semisynthetic penicillin.
References Markovich, M., et al.: Antibiot. Med. Biotekhnol., 31, 603 (1986), Rahman, M., et al.: Biochem. Pharmacol., 46, 1721 (1993), Silva, D., et al.: Med. Biol. Res., 37, 963 (2004),

Fórmula: C₁₉H₁₆ClFN₃O₅S·Na

Cor e Forma: Off-White

Peso molecular: 475.85

Ref: TR-F419200

Flucloxacillin sodium

CAS: 1847-24-1

Flucloxacillin sodium is a beta-lactam antibiotic with action on bacterial cell wall synthesis and is used for treating skin, bone, and respiratory infections.

Fórmula: C₁₉H₁₆ClFN₃NaO₅S

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 475.85 g/mol

Ref: 3D-AF23319