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CAS 18524-94-2
:metil 1-(beta-D-glucopiranosiloxi)-6-hidroxi-7-metil-1,4a,5,6,7,7a-hexahidrociclopenta[c]pirano-4-c
Descrição:
metil 1-(beta-D-glucopiranosiloxi)-6-hidroxi-7-metil-1,4a,5,6,7,7a-hexahidrociclopenta[c]pirano-4-ccarboxilato, identificado pelo número CAS 18524-94-2, é um composto orgânico complexo caracterizado por suas características estruturais únicas. Contém um anel de ciclopentano fundido com uma porção de pirano, o que contribui para sua natureza cíclica e potencial atividade biológica. A presença de um grupo metila e uma porção de glucopiranosilo indica que pode exibir solubilidade em solventes polares e pode participar de ligações de hidrogênio devido aos grupos hidroxila. Este composto também pode possuir propriedades glicosídicas, sugerindo aplicações potenciais em química medicinal ou como um glicosídeo. Sua complexidade estrutural pode influenciar sua reatividade, estabilidade e interação com sistemas biológicos. Além disso, a presença de múltiplos grupos funcionais, incluindo hidroxila e carboxilato, sugere que pode estar envolvido em várias reações químicas, tornando-o de interesse para futuras pesquisas em síntese orgânica e farmacologia. No geral, este composto exemplifica a intrincada relação entre estrutura e função na química orgânica.
Fórmula:C17H26O10
InChI:InChI=1S/C17H26O10/c1-6-9(19)3-7-8(15(23)24-2)5-25-16(11(6)7)27-17-14(22)13(21)12(20)10(4-18)26-17/h5-7,9-14,16-22H,3-4H2,1-2H3/t6-,7+,9-,10+,11+,12+,13-,14+,16-,17-/m0/s1
Chave InChI:InChIKey=AMBQHHVBBHTQBF-UOUCRYGSSA-N
SMILES:O([C@H]1[C@]2([C@@](C(C(OC)=O)=CO1)(C[C@H](O)[C@@H]2C)[H])[H])[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O
Sinónimos:- (1S)-1α-(β-<span class="text-smallcaps">D</span>-Glucopyranosyloxy)-1,4aα,5,6,7,7aα-hexahydro-6α-hydroxy-7α-methylcyclopenta[c]pyran-4-carboxylic acid methyl ester
- 7-Hydroxy-6-desoxyverbenalin
- Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, methyl ester
- Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, methyl ester, (1S,4aS,6S,7R,7aS)-
- Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, methyl ester, [1S-(1α,4aα,6α,7α,7aα)]-
- Loganin
- Loganoside
- Methyl 1-(Hexopyranosyloxy)-6-Hydroxy-7-Methyl-1,4A,5,6,7,7A-Hexahydrocyclopenta[C]Pyran-4-Carboxylate
- NSC 606403
- methyl (1S,4aS,6S,7R,7aS)-1-(beta-D-glucopyranosyloxy)-6-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate
- methyl (1S,4aS,6S,7R,7aS)-1-(hexopyranosyloxy)-6-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate
- Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, methyl ester, [1S-(1α,4aα,6α,7α,7aα)]-
- (1S)-1α-(β-D-Glucopyranosyloxy)-1,4aα,5,6,7,7aα-hexahydro-6α-hydroxy-7α-methylcyclopenta[c]pyran-4-carboxylic acid methyl ester
- Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, methyl ester
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11 produtos.
Loganin
CAS:Loganin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Fórmula:C17H26O10Pureza:(HPLC) ≥99%Cor e Forma:PowderPeso molecular:390.39Cyclopenta[c]pyran-4-carboxylic acid,1-(b-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, methyl ester, (1S,4aS,6S,7R,7aS)-
CAS:Fórmula:C17H26O10Pureza:98%Cor e Forma:SolidPeso molecular:390.3823Loganin
CAS:Fórmula:C17H26O10Pureza:≥ 97.0%Cor e Forma:White to off-white powderPeso molecular:390.38Loganin
CAS:Fórmula:C17H26O10Pureza:>98.0%(HPLC)(qNMR)Cor e Forma:White to Almost white powder to crystalPeso molecular:390.39Loganin
CAS:Loganin is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively. Loganin has neuroprotective, anti-amnesic, anti-inflammatory and anti-shock effects, it also exhibits protective effects against hepatic injury and other diabetic complications associated with abnormal metabolic states and inflammation caused by oxidative stress and advanced glycation endproduct formation. Loganin can attenuate neuroinflammatory responses through the inactivation of NF-κB by NF-κB dependent inflammatory pathways and phosphorylation of MAPK in Aβ25-35-induced PC12 cells, and can protect against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of JNK, p38, and ERK 1/2 MAPKs in SH-SY5Y cells.Fórmula:C17H26O10Pureza:95%~99%Peso molecular:390.385Loganin
CAS:<p>Loganin inhibits Cox-1, suppresses TNF-α, and has antioxidant and anti-melanogenic properties.</p>Fórmula:C17H26O10Pureza:99.01% - >99.99%Cor e Forma:White PowderPeso molecular:390.38Loganin
CAS:Natural glycosideFórmula:C17H26O10Pureza:≥ 95.0 % (HPLC)Cor e Forma:PowderPeso molecular:390.39Loganin
CAS:<p>Loganin is a bioactive iridoid compound, which is a type of secondary metabolite typically found in plants. It is primarily derived from sources such as the genera Strychnos and Gentiana, among others. Loganin operates through various biological pathways, influencing enzymatic and receptor activities that contribute to its pharmacological effects. These activities include anti-inflammatory, antioxidant, and neuroprotective actions, making Loganin a compound of interest in several areas of medical research.</p>Fórmula:C17H26O10Pureza:Min. 94 Area-%Cor e Forma:PowderPeso molecular:390.39 g/molLoganin
CAS:Produto Controlado<p>Applications An iridoid glycoside that exhibits protective effects against hepatic injury and other diabetic complications associated with abnormal metabolic states and inflammation caused by oxidative stress and advanced glycation endproduct formation. A potential anti-amnesic agent.<br>References Yamabe, N. et al.: Eur. J. Pharmmacol., 648, 179 (2010); de Carman Recio, M. et al.: Planta Medica, 3, 232 (1994); Kwon, S. et al.: Eur. J. Pharmacol., 619, 44 (2009);<br></p>Fórmula:C17H26O10Cor e Forma:NeatPeso molecular:390.38
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