CAS 1866-15-5

Iodeto de acetiltiocolina

Descrição:

Iodeto de acetiltiocolina é um composto de amônio quaternário que serve como substrato para a enzima acetilcolinesterase e é frequentemente utilizado em pesquisas bioquímicas, particularmente em estudos relacionados à neurotransmissão. É um análogo sintético do neurotransmissor acetilcolina, apresentando um grupo tioéter que melhora sua estabilidade e reatividade. O composto é tipicamente um sólido cristalino branco a off-white, solúvel em água e solventes orgânicos polares. Sua estrutura inclui um grupo acetila ligado a uma parte de tiocolina, que contribui para sua capacidade de imitar a ação da acetilcolina nos receptores colinérgicos. Iodeto de acetiltiocolina é comumente utilizado em ensaios para medir a atividade enzimática e em estudos farmacológicos para investigar as vias de sinalização colinérgicas. Devido à sua natureza quaternária, não atravessa facilmente as membranas biológicas, tornando-o útil para estudos in vitro. Devem ser observadas precauções de segurança ao manusear este composto, pois pode representar riscos à saúde se ingerido ou inalado.

Fórmula: C₇H₁₆NOS·I

InChI: InChI=1S/C7H16NOS.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

Chave InChI: InChIKey=NTBLZMAMTZXLBP-UHFFFAOYSA-M

SMILES: C(CSC(C)=O)[N+](C)(C)C.[I-]

Sinónimos:

• (2-Mercaptoethyl)trimethylammonium iodide acetate
• 2-(Acetylsulfanyl)-N,N,N-trimethylethanaminium iodide
• 2-Acetylthioethyltrimethylammonium Iodide
• Acetic acid, thio-, S-ester with (2-mercaptoethyl)trimethylammonium iodide
• Acetylthiocholine diiodide
• Acetylthiocholine iodide
• Ammonium, (2-mercaptoethyl)trimethyl-, iodide, acetate
• Ethanaminium, 2-(acetylthio)-N,N,N-trimethyl-, iodide
• [2-(Acetylsulfanyl)ethyl]trimethylazanium iodide
• [2-(Acetylthio)ethyl](trimethyl)ammonium iodide
• ethanaminium, 2-(acetylthio)-N,N,N-trimethyl-, iodide (1:1)

Acetylthiocholine Iodide

CAS: 1866-15-5

Fórmula: C₇H₁₆INOS

Pureza: >98.0%(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 289.18

Ref: 3B-A0116

Acetylthiocholine iodide

CAS: 1866-15-5

Fórmula: C₇H₁₆INOS

Pureza: 98%

Cor e Forma: Solid, White - Almost white powder

Peso molecular: 289.18

Ref: 10-F228086

S-Acetylthiocholine iodide, 98%

CAS: 1866-15-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₇H₁₆INOS

Pureza: 98%

Cor e Forma: White, Crystals or powder or crystalline powder

Peso molecular: 289.18

Ref: 02-A16802

Ethanaminium, 2-(acetylthio)-N,N,N-trimethyl-, iodide

CAS: 1866-15-5

Fórmula: C₇H₁₆INOS

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 289.1775

Ref: IN-DA00I1TX

Acetylthiocholine iodide

CAS: 1866-15-5

Fórmula: C₇H₁₆INOS

Pureza: (Titration) ≥ 98.0%

Cor e Forma: White or almost white crystalline powder

Peso molecular: 289.18

Ref: 7W-GE4789

[2-(acetylthio)ethyl](trimethyl)ammonium iodide

CAS: 1866-15-5

[2-(acetylthio)ethyl](trimethyl)ammonium iodide

Pureza: 98%

Peso molecular: 289.1775g/mol

Ref: 54-OR27854

S-Acetylthiocholine iodide

CAS: 1866-15-5

S-Acetylthiocholine iodide

Fórmula: C₇H₁₆NOS·I

Pureza: 98%

Cor e Forma: white solid

Peso molecular: 289.1775g/mol

Ref: 54-BIA4001

Acetylthiocholine Iodide

Produto Controlado

CAS: 1866-15-5

Applications Acetylthiocholine Iodide functions as a potential biomarkers for the dictation of diseases or biological conditions (in-vitro) in marines and also functions in ecotoxically studies in marine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gomes, I. D. L., et al.: Mar. Pollut.Bull. (2014), 85(1), 179-185

Fórmula: C₇H₁₆NOS·I

Cor e Forma: Neat

Peso molecular: 289.1775

Ref: TR-A164610

S-Acetylthiocholine iodide

CAS: 1866-15-5

S-Acetylthiocholine iodide is an acetylcholinesterase substrate for the colorimetric determination of acetylcholinesterase activity. In this assay the production of thiocholine formed in the hydrolysis of acetylthiocholine is measured by coupling of the reactive thiol with DTNB to give a thionitrobenzoate (TNB). The TNB is a yellow anion and its formation can be measured spectrometrically. Nicotinic acetylcholine receptor agonist.

Fórmula: C₇H₁₆INOS

Peso molecular: 289.18 g/mol

Ref: 3D-A-1700

S-Acetylthiocholine iodide

CAS: 1866-15-5

S-Acetylthiocholine iodide is an inhibitor of acetylcholinesterase. This compound has been shown to be effective in a variety of biochemical and experimental models, with the optimum concentration at 5-10 mM. S-Acetylthiocholine iodide has also been shown to have inhibitory properties against other enzymes, such as brain functions and choline esterase. The inhibition of these enzymes may lead to the development of novel biomarkers for the diagnosis of diseases such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.

Fórmula: C₇H₁₆INOS

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 289.18 g/mol

Ref: 3D-FA33157

S-Acetylthiocholine Iodide extrapure AR, 99%

CAS: 1866-15-5

Fórmula: C₇H₁₆NOSI

Pureza: min. 99%

Cor e Forma: White to off - white, Crystalline powder, Clear

Peso molecular: 289.17

Ref: SR-38998