CAS 1871-22-3

Azul de tetrazólio

Descrição:

Azul de tetrazólio, também conhecido como cloreto de 2,3,5-trifeniltetrazólio (TTC), é um composto químico comumente utilizado em aplicações biológicas e bioquímicas, particularmente em ensaios de viabilidade celular. É um indicador redox que sofre uma mudança de cor ao ser reduzido, convertendo-se de uma forma solúvel amarela para um produto de formazano vermelho insolúvel na presença de células viáveis. Essa propriedade o torna útil para avaliar a atividade metabólica em organismos vivos, uma vez que apenas células metabolicamente ativas podem reduzir o sal de tetrazólio. Azul de tetrazólio é tipicamente utilizado em microbiologia, histologia e várias aplicações de pesquisa para avaliar a proliferação celular e a citotoxicidade. O composto é geralmente estável sob condições laboratoriais padrão, mas deve ser manuseado com cuidado, pois pode ser tóxico em certas concentrações. Sua solubilidade em água e solventes orgânicos permite aplicações versáteis em diferentes configurações experimentais. No geral, Azul de tetrazólio serve como uma ferramenta valiosa no estudo de processos celulares e na avaliação da saúde celular.

Fórmula: C₄₀H₃₂N₈O₂·2Cl

InChI: InChI=1S/C40H32N8O2.2ClH/c1-49-37-27-31(23-25-35(37)47-43-39(29-15-7-3-8-16-29)41-45(47)33-19-11-5-12-20-33)32-24-26-36(38(28-32)50-2)48-44-40(30-17-9-4-10-18-30)42-46(48)34-21-13-6-14-22-34;;/h3-28H,1-2H3;2*1H/q+2;;/p-2

Chave InChI: InChIKey=MUUHXGOJWVMBDY-UHFFFAOYSA-L

SMILES: O(C)C1=C(N2[N+](=NC(=N2)C3=CC=CC=C3)C4=CC=CC=C4)C=CC(=C1)C5=CC(OC)=C(C=C5)N6[N+](=NC(=N6)C7=CC=CC=C7)C8=CC=CC=C8.[Cl-]

Sinónimos:

• 2,2′,5,5′-Tetraphenyl-3,3′-(3,3′-dimethoxy-4,4′-diphenylene)ditetrazolium chloride
• 2,2′-(m,m′-Dimethoxy-p,p′-biphenylene)bis(3,5-diphenyltetrazolium chloride)
• 2H-Tetrazolium, 2,2′-(3,3′-dimethoxy[1,1′-biphenyl]-4,4′-diyl)bis[3,5-diphenyl-, chloride (1:2)
• 2H-Tetrazolium, 2,2′-(3,3′-dimethoxy[1,1′-biphenyl]-4,4′-diyl)bis[3,5-diphenyl-, dichloride
• 2H-Tetrazolium, 3,3′-(3,3′-dimethoxy-4,4′-biphenylylene)bis[2,5-diphenyl-, dichloride
• 3,3-(3,3-Dimethoxy-4,4-biphenylene)bis(2,5-diphenyl-2H-tetrazolium chloride)
• 3,3′-(3,3′-Dimethoxy-4,4′-biphenylylene)bis[2,5-diphenyl-2H-tetrazolium chloride]
• 3,3′-Dianisolebis[4,4′-(3,5-diphenyl)tetrazolium chloride]
• BT (dye)
• BTC
• Blue Tetrazolium chloride
• Ditetrazolium chloride
• NSC 27623
• Tetrazole blue
• Tetrazolium Blue BT
• Tetrazolium Blue Chloride
• Tetrazolium blue

Blue Tetrazolium

CAS: 1871-22-3

Fórmula: C₄₀H₃₂Cl₂N₈O₂

Pureza: >95.0%(T)

Cor e Forma: White to Amber powder to crystal

Peso molecular: 727.65

Ref: 3B-D0943

Blue Tetrazolium chloride

CAS: 1871-22-3

Blue Tetrazolium chloride is useful in the prepartion of DNA cation complexes and immunoadsorbents for anti-DNA antibodies. It is used in assay of reducing sugars. In combination with 4-nitrocatechol, tetrazolium blue chloride forms a ternary complex with molybdenum(VI) for extraction and spectropho

Fórmula: C₄₀H₃₆Cl₂N₈O₂

Cor e Forma: Pale yellow to yellow, Powder

Peso molecular: 731.68

Ref: 02-A12502

3,3'-(3,3'-Dimethoxy-[1,1'-biphenyl]-4,4'-diyl)bis(2,5-diphenyl-2H-tetrazol-3-ium) chloride

CAS: 1871-22-3

Fórmula: C₄₀H₃₂Cl₂N₈O₂

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 727.6405

Ref: IN-DA007S1S

Tetrazolium Blue Chloride

CAS: 1871-22-3

Fórmula: C₄₀H₃₂Cl₂N₈O₂

Pureza: (HPLC) ≥ 95.0%

Cor e Forma: Yellow powder

Peso molecular: 727.66

Ref: 7W-GT7170

Blue Tetrazolium [for Biochemical Research]

CAS: 1871-22-3

Fórmula: C₄₀H₃₂Cl₂N₈O₂

Pureza: >95.0%(T)

Cor e Forma: White to Amber powder to crystal

Peso molecular: 727.65

Ref: 3B-B3581

3,3'-Dianisole-4,4'-bis(3,5-diphenyltetrazolium chloride

CAS: 1871-22-3

3,3'-Dianisole-4,4'-bis(3,5-diphenyltetrazolium chloride

Fórmula: C₄₀H₃₂N₈O₂·2Cl

Pureza: By hplc: 98% (Typical Value in Batch COA)

Cor e Forma: yellow powder

Peso molecular: 727.64g/mol

Ref: 54-BIT3025

Tetrazolium Blue Chloride (>90%)

Produto Controlado

CAS: 1871-22-3

Stability Light Sensitive
Applications Tetrazolium Blue Chloride is used for its anti-plasmodium activity. Also used in the study of inhibition of diphenyltetrazolium bromide (MTT) reduction by β-amyloid peptides resulting in neurodegenerative manifestations. Dyes and metabolites.
References Cui, X. et al.: Bioorg, Med. Chem., 16, 1927 (2008); Shearman, M. et al.: J. Neurochem, 65, 218 (1995);

Fórmula: C₄₀H₃₂N₈O₂·2Cl

Pureza: >90%

Cor e Forma: Neat

Peso molecular: 727.6

Ref: TR-T310700

Tetrazolium blue chloride

CAS: 1871-22-3

Tetrazolium blue chloride is a chemical compound that is used in the diagnosis of leukemia. It is a tetrazolium salt that reacts with reduced nicotinamide adenine dinucleotide (NADH) and produces an insoluble blue product. Tetrazolium blue chloride has been shown to be effective in treating human leukemic cells by causing DNA damage, which leads to cell death. Tetrazolium blue chloride has also been found to be an anti-inflammatory agent due to its ability to inhibit prostaglandin synthesis and production of reactive oxygen species.

Fórmula: C₄₀H₃₂N₈O₂·2Cl

Pureza: 90 To 110%

Cor e Forma: Yellow Powder

Peso molecular: 727.64 g/mol

Ref: 3D-ET11162

Blue Tetrazolium chloride

CAS: 1871-22-3

Blue tetrazolium chloride is an analytical method that is used to measure the rate of microbial growth. It has been used to study the effects of radiation, and it has also been shown to be a useful tool for detecting the presence of bacteria in biological samples. Blue tetrazolium chloride can be used as a selective agent for dextran sulfate and caffeic acid, which are present in human polymorphonuclear leukocytes, but not in squamous cells. This compound can also be used to detect the presence of antioxidant vitamins such as vitamin C and vitamin E. The optimum concentration for this compound is 2-3 microliters per milliliter in 0.1N HCl solution at room temperature.

Fórmula: C₄₀H₃₂Cl₂N₈O₂

Peso molecular: 727.64 g/mol

Ref: 3D-B-4200

Blue Tetrazolium Chloride (BTC, Tetrazolium Blue Chloride) extrapure AR

CAS: 1871-22-3

Fórmula: C₄₀H₃₂O₂N₈Cl₂

Cor e Forma: Lemon yellow, Crystalline powder, Clear, Yellow

Peso molecular: 727.66

Ref: SR-22649