CAS 1879-72-7

(11β,16α)-9-Flúor-11,17-diidroxi-16-metil-21-(1-oxo-3-fenilpropoxi)pregna-1,4-dieno-3,20-diona

Descrição:

A substância química conhecida como "(11β,16α)-9-Flúor-11,17-diidroxi-16-metil-21-(1-oxo-3-fenilpropoxi)pregna-1,4-dieno-3,20-diona," com o número CAS 1879-72-7, é um corticosteroide sintético. Apresenta propriedades anti-inflamatórias e imunossupressoras, tornando-a útil em várias aplicações terapêuticas, particularmente no tratamento de condições como asma, alergias e distúrbios autoimunes. A estrutura deste composto apresenta um átomo de flúor, grupos hidroxila e uma cadeia lateral de fenilpropóxido, contribuindo para sua atividade biológica e farmacocinética. A presença da estrutura esteroide pregnano é característica dos corticosteroides, que são derivados do colesterol. A estereoisomeria específica deste composto, indicada pela nomenclatura, desempenha um papel crucial em sua interação com os receptores de glicocorticoides, influenciando sua eficácia e potência. Assim como muitos corticosteroides, também pode ter efeitos colaterais, incluindo impactos potenciais no metabolismo e na função imunológica, exigindo consideração cuidadosa em seu uso clínico.

Fórmula: C₃₁H₃₇FO₆

InChI: InChI=1/C31H37FO6/c1-19-15-24-23-11-10-21-16-22(33)13-14-28(21,2)30(23,32)25(34)17-29(24,3)31(19,37)26(35)18-38-27(36)12-9-20-7-5-4-6-8-20/h4-8,13-14,16,19,23-25,34,37H,9-12,15,17-18H2,1-3H3/t19-,23+,24+,25+,28+,29+,30+,31+/m1/s1

Chave InChI: InChIKey=CTKMBLPPDDQOSU-JPYVRCQISA-N

SMILES: F[C@@]12[C@]([C@]3([C@@](C)([C@](C(COC(CCC4=CC=CC=C4)=O)=O)(O)[C@H](C)C3)C[C@@H]1O)[H])(CCC=5[C@]2(C)C=CC(=O)C5)[H]

Sinónimos:

• (11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl 3-Phenylpropanoate
• Dexamethasone 21-hydrocinnamate
• Dexamethasone 21-phenylpropionate
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)-, (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-hydrocinnamate
• Dexamethasone 21-(3-phenylpropionate)
• (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)pregna-1,4-diene-3,20-dione
• Dexamethasone Phenylpropionate
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)-, (11.beta.,16.alpha.)-
• [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 3-phenylpropanoate
• 9-Fluoro-11β,17-dihydroxy-16α-methyl-21-(1-oxo-3-phenylpropoxy)pregna-1,4-diene-3,20-dione

Dexamethasone Phenylpropionate

CAS: 1879-72-7

Fórmula: C₃₁H₃₇FO₆

Pureza: 95%

Peso molecular: 524.6203

Ref: IN-DA002GK5

Dexamethasone Phenylpropionate

CAS: 1879-72-7

Fórmula: C₃₁H₃₇FO₆

Cor e Forma: White To Off-White Solid

Peso molecular: 524.63

Ref: 4Z-D-3629

Dexamethasone Phenylpropionate

Produto Controlado

CAS: 1879-72-7

Fórmula: C₃₁H₃₇FO₆

Cor e Forma: Neat

Peso molecular: 524.62

Ref: TR-D222830

Dexamethasone Phenylpropionate

CAS: 1879-72-7

Fórmula: C₃₁H₃₇FO₆

Peso molecular: 524.63

Ref: ST-EA-CP-D17070

Dexamethasone 21-(3-phenylpropionate)

CAS: 1879-72-7

Dexamethasone 21-(3-phenylpropionate) is a corticosteroid that is used for the treatment of a variety of inflammatory skin conditions. Dexamethasone 21-(3-phenylpropionate) has been shown to be effective in the treatment of cutaneous lesions in mice and rabbits. This drug also has an anti-inflammatory effect, which may be due to its ability to inhibit cytokine production. Dexamethasone 21-(3-phenylpropionate) is not metabolized by liver enzymes and has a long half life, making it more predictable than prednisolone. This medication should not be used during pregnancy or if you are trying to become pregnant, as it may cause abortion or premature birth. It should also not be used by women who are breastfeeding, as it can pass through breast milk and affect the baby.

Fórmula: C₃₁H₃₇FO₆

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 524.62 g/mol

Ref: 3D-FD31959