CAS 189028-95-3

(4S)-3-[(5S)-5-(4-fluorofenil)-5-hidroxi-1-oxopentil]-4-fenil-2-oxazolidinona

Descrição:

A substância química conhecida como (4S)-3-[(5S)-5-(4-fluorofenil)-5-hidroxi-1-oxopentil]-4-fenil-2-oxazolidinona, com o número CAS 189028-95-3, é caracterizada por sua estrutura central de oxazolidinona, que é um composto heterocíclico de cinco membros contendo tanto nitrogênio quanto oxigênio. Este composto apresenta um centro quiral na posição 4 do anel de oxazolidinona, contribuindo para sua estereoquímica e potencial atividade biológica. A presença de um grupo 4-fluorofenila e um moiety de hidroxi cetona sugere que pode exibir interações significativas com alvos biológicos, possivelmente influenciando suas propriedades farmacológicas. A estrutura molecular do composto indica potencial para aplicações em química medicinal, particularmente no desenvolvimento de antibióticos ou outros agentes terapêuticos. Sua solubilidade, estabilidade e reatividade dependeriam dos grupos funcionais específicos e sua disposição, o que pode afetar seu comportamento em sistemas biológicos. No geral, este composto representa uma classe de moléculas que podem ter implicações importantes na descoberta e desenvolvimento de medicamentos.

Fórmula: C₂₀H₂₀FNO₄

InChI: InChI=1S/C20H20FNO4/c21-16-11-9-15(10-12-16)18(23)7-4-8-19(24)22-17(13-26-20(22)25)14-5-2-1-3-6-14/h1-3,5-6,9-12,17-18,23H,4,7-8,13H2/t17-,18+/m1/s1

Chave InChI: InChIKey=AVAZNWOHQJYCEL-MSOLQXFVSA-N

SMILES: C(CCC[C@H](O)C1=CC=C(F)C=C1)(=O)N2[C@H](COC2=O)C3=CC=CC=C3

Sinónimos:

• (4S)-3-[(5R)-5-(4-Fluorophenyl)-5-Hydroxypentanoyl]-4-pheny-1,3-oxzolidin-2-One
• (4S)-3-[(5S)-5-(4-Fluoro phenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one
• (4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-2-oxazolidinone
• (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one
• (4S)-4-Phenyl-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one
• (S)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
• 2-Oxazolidinone, 3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-, (4S)-
• 2-Oxazolidinone, 3-[5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-, [S-(R*,R*)]-
• 3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one
• 3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-,(4S)-2-Oxazolidinone
• 3-[5-(4-Fluoro-Phenyl)-5-Hydroxy-Pentanoyl]-5-Phenyl-Oxazolidin-2-One

2-Oxazolidinone, 3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-, (4S)-

CAS: 189028-95-3

Fórmula: C₂₀H₂₀FNO₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 357.3755

Ref: IN-DA002HQD

(S)-3-((S)-5-(4-Fluorophenyl)-5-Hydroxypentanoyl)-4-Phenyloxazolidin-2-One

CAS: 189028-95-3

(S)-3-((S)-5-(4-Fluorophenyl)-5-Hydroxypentanoyl)-4-Phenyloxazolidin-2-One

Pureza: 99%

Peso molecular: 357.38g/mol

Ref: 54-PC109163

Ezetimibe Impurity 45

CAS: 189028-95-3

Fórmula: C₂₀H₂₀FNO₄

Cor e Forma: White To Off-White Solid

Peso molecular: 357.38

Ref: 4Z-E-0652

(S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one

CAS: 189028-95-3

Pureza: 95.0%

Cor e Forma: Solid

Peso molecular: 357.3810119628906

Ref: 10-F237771

3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one

Produto Controlado

CAS: 189028-95-3

Applications 3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one is an intermediate of Ezetimibe (E975000, E975002), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.
References Singh, A., et. al.: J. Molecular Catal. B., 85, 99 (2013); van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997); van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)

Fórmula: C₂₀H₂₀FNO₄

Cor e Forma: Neat

Peso molecular: 357.38

Ref: TR-F595465

Ezetimibe Impurity 16

CAS: 189028-95-3

Fórmula: C₂₀H₂₀FNO₄

Peso molecular: 357.38

Ref: ST-EA-CP-E6041

(S)-3((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one

CAS: 189028-95-3

(S)-3((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one is an enzyme inhibitor that interrupts the biosynthesis of glucose by inhibiting the activity of the enzyme glucose dehydrogenase. This drug has been shown to be efficacious against a number of strains, including E. coli and S. typhimurium, but not other bacteria such as escherichia or mycobacteria. (S)-3((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one is used in medicines to treat cardiovascular diseases. It has been shown to inhibit the production of dinucleotide phosphate, which is essential for the synthesis of nucleic acids and energy production in cells. The reaction system is circularly closed by this molecule.br>br>

Pureza: Min. 95%

Ref: 3D-FF57617

(S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one

CAS: 189028-95-3

(S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one is a useful organic compound for research related to life sciences. The catalog number is T66207 and the CAS number is 189028-95-3.

Fórmula: C₂₀H₂₀FNO₄

Cor e Forma: Solid

Peso molecular: 357.381

Ref: TM-T66207