CAS 18942-49-9
:N-terc-butiloxicarbonil-D-fenilalanina
Descrição:
N-terc-butiloxicarbonil-D-fenilalanina, comumente referido como Boc-D-fenilalanina, é um derivado de aminoácido caracterizado pela presença de um grupo protetor tert-butiloxicarbonila (Boc) ligado ao grupo amino da D-fenilalanina. Este composto é tipicamente utilizado na síntese de peptídeos como um grupo protetor que facilita a modificação seletiva de aminoácidos sem interferir com outros grupos funcionais. É um sólido branco a off-white que é solúvel em solventes orgânicos como diclorometano e dimetilformamida, mas geralmente insolúvel em água. O grupo Boc é conhecido por sua estabilidade em condições básicas e pode ser facilmente removido em condições ácidas, tornando-se uma ferramenta valiosa na síntese orgânica. A presença do grupo fenila contribui para as características hidrofóbicas do composto, influenciando suas interações em sistemas biológicos. Como uma molécula quiral, existe em duas formas enantioméricas, sendo a forma D utilizada em várias aplicações bioquímicas. No geral, a Boc-D-fenilalanina é significativa no campo da química medicinal e da pesquisa de peptídeos.
Fórmula:C14H19NO4
InChI:InChI=1S/C14H19NO4/c1-14(2,3)19-13(18)15-11(12(16)17)9-10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,15,18)(H,16,17)/t11-/m1/s1
Chave InChI:InChIKey=ZYJPUMXJBDHSIF-LLVKDONJSA-N
SMILES:[C@H](CC1=CC=CC=C1)(NC(OC(C)(C)C)=O)C(O)=O
Sinónimos:- (2R)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoic acid
- (2R)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoic acid
- (2R)-2-[(tert-Butoxycarbonyl)amino]-3-phenylpropionic acid
- (2R)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoate
- (2R)-2-[[(tert-Butoxy)carbonyl]amino]-3-phenylpropanoic acid
- (R)-2-((tert-Butoxycarbonyl)amino)-3-phenylpropionic acid
- (R)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoic acid
- (R)-N-(tert-Butoxycarbonyl)phenylalanine
- <span class="text-smallcaps">D</span>-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-
- Alanine, N-carboxy-3-phenyl-, N-tert-butyl ester, <span class="text-smallcaps">D</span>-
- BOC-<span class="text-smallcaps">D</span>-phenylalanine
- Boc-D-Phe-OH
- N-(tert-Butoxycarbonyl)-D-phenylalanine
- N-BOC-<span class="text-smallcaps">D</span>-phenylalanine
- N-Boc-D-phenylalanine
- N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">D</span>-phenylalanine
- N-tert-Butoxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
- N-tert-Butyloxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
- tert-Butoxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
- tert-Butyloxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
- tert-Butoxycarbonyl-D-phenylalanine
- Alanine, N-carboxy-3-phenyl-, N-tert-butyl ester, D-
- D-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-
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13 produtos.
N-(tert-Butoxycarbonyl)-D-phenylalanine
CAS:Fórmula:C14H19NO4Pureza:>98.0%(T)Cor e Forma:White to Almost white powder to crystalPeso molecular:265.31N-Boc-D-phenylalanine, 98%
CAS:<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>Fórmula:C14H19NO4Pureza:98%Cor e Forma:Crystals or powder or crystalline powder, WhitePeso molecular:265.31Boc-D-Phe-OH
CAS:<p>Bachem ID: 4000781.</p>Fórmula:C14H19NO4Pureza:> 99%Cor e Forma:WhitePeso molecular:265.31Boc-D-phenylalanine
CAS:<p>Boc-D-phenylalanine</p>Fórmula:C14H19NO4Pureza:98%Cor e Forma: white to off-white powderPeso molecular:265.30g/molBoc-D-Phe-OH
CAS:<p>Boc-D-Phe-OH is an antimicrobial peptide that is a small molecule with a molecular weight of 254.8. It has been shown to have anti-tumor activity, and can be used as an alternative to conventional chemotherapeutic drugs in the treatment of cancer. Boc-D-Phe-OH binds to the hydrophobic region on the surface of cells and disrupts the cell's membrane, causing cell death by apoptosis. This peptide also shows antibacterial activity against gramicidin S, which is a Gram-positive antibiotic that belongs to the polymyxins class. The antibacterial activity of this peptide may be due to its ability to bind to divalent cations such as calcium ions and magnesium ions. Boc-D-Phe-OH has been synthesized using a method that is both efficient and rapid (less than 12 hours). It has also been shown that this peptide does not show any</p>Fórmula:C14H19NO4Pureza:Min. 95%Peso molecular:265.3 g/molBoc-D-Phe-OH
CAS:<p>M03311 - Boc-D-Phe-OH</p>Fórmula:C14H19NO4Pureza:98%Cor e Forma:Solid, Crystalline Powder or PowderPeso molecular:265.309N-Boc-D-phenylalanine
CAS:<p>D-Phenylalanine is a molecule that is used in the synthesis of peptidomimetics. It has been shown to have a high efficiency method in the synthesis of N-Boc-D-phenylalanine, which can be used as a glycosidic bond precursor. This chemical has been shown to have anti-tumor properties and it may be useful in binding experiments with ferrocene. The compound can also form hydrogen bonds with acids, such as the acid catalyst found in the digestive system.</p>Fórmula:C14H19NO4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:265.31 g/molBOC-D-Phenylalanine extrapure, 99%
CAS:Fórmula:C14H19NO4Pureza:min. 99%Cor e Forma:White, PowderPeso molecular:265.30Boc-D-Phenylalanine
CAS:Produto Controlado<p>Applications Boc-D-Phenylalanine is used in the synthesis of benzo[de][1,7]napthyridinones as PARP1 inhibitors. Also it is an important reagent in the preparation of proline-containing, β-turn mimetic cycle tetrapeptides.<br>References Ye, Na. et al.: J. Med. Chem., 56, 2885 (2013); Chouhan, G. et al.: Org. Lett., 15, 1206 (2013);<br></p>Fórmula:C14H19NO4Cor e Forma:NeatPeso molecular:265.3
