CAS 19057-60-4

(+)-Dioscina

Descrição:

(+)-Dioscina, com o número CAS 19057-60-4, é uma saponina esteroidal de ocorrência natural, extraída principalmente de várias fontes vegetais, particularmente do gênero Dioscorea, comumente conhecido como inhame. Este composto é caracterizado por sua complexa estrutura glicosídica, que inclui uma espinha dorsal esteroide ligada a moieties de açúcar. (+)-Dioscina exibe uma variedade de atividades biológicas, incluindo propriedades anti-inflamatórias, antioxidantes e potenciais anticancerígenas, tornando-o de interesse na pesquisa farmacológica. Sua solubilidade é geralmente baixa em água, mas pode se dissolver em solventes orgânicos, o que é típico para muitas saponinas. A estrutura do composto contribui para sua capacidade de interagir com as membranas celulares, influenciando processos celulares. Além disso, (+)-Dioscina tem sido estudado por seus potenciais efeitos no metabolismo do colesterol e seu papel na medicina tradicional. Assim como muitos produtos naturais, os processos de extração e purificação podem afetar significativamente sua bioatividade e eficácia, destacando a importância dos métodos de obtenção e preparação na pesquisa e aplicação.

Fórmula: C₄₅H₇₂O₁₆

InChI: InChI=1/C45H72O16/c1-19-9-14-45(54-18-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(52)34(50)32(48)22(4)56-41)37(53)38(29(17-46)58-42)59-40-35(51)33(49)31(47)21(3)55-40/h7,19-22,24-42,46-53H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27?,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1

Chave InChI: InChIKey=VNONINPVFQTJOC-ZGXDEBHDSA-N

SMILES: C[C@@]12[C@@]3([C@](C[C@]1([C@]4([C@](CC2)([C@]5(C)C(=CC4)C[C@@H](O[C@H]6[C@H](O[C@H]7[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O7)[C@@H](O)[C@H](O[C@H]8[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O8)[C@@H](CO)O6)CC5)[H])[H])[H])(O[C@@]9([C@H]3C)CC[C@@H](C)CO9)[H])[H]

Sinónimos:

• (3beta,14xi,25R)-spirost-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[6-deoxy-alpha-L-mannopyranosyl-(1->4)]-beta-D-glucopyranoside
• (3beta,25R)-spirost-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[6-deoxy-alpha-L-mannopyranosyl-(1->4)]-beta-D-glucopyranoside
• (3β,25R)-Spirost-5-en-3-yl O-6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl-(1→2)-O-[6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→4)]-β-<smallcap>D</span>-glucopyranoside
• 3-O-β-<span class="text-smallcaps">D</smallcap>-α-<smallcap>L</smallcap>-Rhamnopyranosyl(1→4)-[α-<smallcap>L</smallcap>-rhamnopyranosyl(1→2)]-β-<smallcap>D</span>-glucopyranoside-diosgenin
• Beta-D-Glucopyranoside,(3-Beta,25R)-Spirost-5-En-3-Ylo-6-Deoxy-Alpha-L-Mannop
• Collettiside III
• Collettisideiii
• Dioscin(P)
• Dioscine
• Diosgenin 3-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→2)-[α-<smallcap>L</smallcap>-rhamnopyranosyl-(1→4)]-β-<smallcap>D</span>-glucopyranoside
• Diosgenin 3-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→4)-[α-<smallcap>L</smallcap>-rhamnopyranosyl-(1→2)]-β-<smallcap>D</span>-glucopyranoside
• Diosgenin bis-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→2 and 1→4)-β-<smallcap>D</span>-glucopyranoside
• Paris III
• Parissaponin III
• Polyphyllin III
• Yranosyl-(1-2)-O-(6-Deoxy-Alpha-L-Mannopyranosyl)-(1-4))-
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→2)-O-[6-deoxy-α-<smallcap>L</span>-mannopyranosyl-(1→4)]-
• β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-
• Dioscin
• Diosgenin bis-α-L-rhamnopyranosyl-(1→2 and 1→4)-β-D-glucopyranoside
• (3β,25R)-Spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside
• [(25R)-Spirosta-5-ene-3β-yl]2-O,4-O-bis(α-L-rhamnopyranosyl)-β-D-glucopyranoside
• (25R)-3β-[2-O,4-O-Bis(α-L-rhamnopyranosyl)-β-D-glucopyranosyloxy]spirosta-5-ene
• Dioscin Green Plants Extracts 19057-60-4 Dioscorea Nipponica Source
• Dioscin / Diosgenyl 2,4-Di-O-α-L-rhamnopyranosyl-β-D-glucopyranoside
• Diosgenin bis-alpha-L-rhamnopyranosyl)-(1-2 and 1-4)-beta-D-glucopyranoside
• Dioscin(Collettiside III)
• DIOSCIN(RG)
• Ccris 4123
• Dioscin 19057-60-4
• beta-D-Glucopyranoside, (3beta,25R)-spirost-5-en-3-yl o-6-deoxy-alpha-L-mannopyranosyl-(1-2)-o-(6-deoxy-alpha-L-mannopyranosyl-(1-4))-
• Dioscin (6ci,7ci,8ci)
• [(25R)-Spirosta-5-ene-3β-yl]2-O,4-O-di-α-L-rhamnopyranosyl-β-D-glucopyranoside
• Dioscin, 98%, from Dioscorea opposita Thunb.
• Yam Extract Dioscin
• Dioscin USP/EP/BP
• ioscin
• [(25R)-Spirost-5-en-3β-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-4-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside

Dioscin

CAS: 19057-60-4

Fórmula: C₄₅H₇₂O₁₆

Pureza: >95.0%(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 869.06

Ref: 3B-D5167

Dioscin

CAS: 19057-60-4

Dioscin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₄₅H₇₂O₁₆

Pureza: (HPLC) ≥98%

Cor e Forma: Powder

Peso molecular: 869.06

Ref: 11-3515S

Dioscin

CAS: 19057-60-4

Fórmula: C₄₅H₇₂O₁₆

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 869.0436

Ref: IN-DA00I2TD

Dioscin

CAS: 19057-60-4

Dioscin

Pureza: ≥98%

Peso molecular: 869.04g/mol

Ref: 54-BUP00105

Dioscin

CAS: 19057-60-4

Dioscin

Pureza: 98%

Peso molecular: 869.04g/mol

Ref: 54-OR1026166

Dioscin

CAS: 19057-60-4

Dioscin, a saponin extracted from the root of Polygonatum Zanlanscianense Pamp, can markedly inhibit proliferation of Hela cells, underwent apoptosis in dose- and time-dependent manner.

Fórmula: C₄₅H₇₂O₁₆

Pureza: 95%~99%

Cor e Forma: Powder

Peso molecular: 869.055

Ref: BP-BP0503

Dioscin

CAS: 19057-60-4

Ref: 7W-GC9259

Dioscin

CAS: 19057-60-4

Dioscin (Collettiside III) is a saponin with antitumor activities.

Fórmula: C₄₅H₇₂O₁₆

Pureza: 99.85% - 99.87%

Cor e Forma: Solid

Peso molecular: 869.04

Ref: TM-T6473

Dioscin

CAS: 19057-60-4

Fórmula: C₄₅H₇₂O₁₆

Peso molecular: 869.06

Ref: 4Z-G-157006

Dioscin

CAS: 19057-60-4

Natural glycoside

Fórmula: C₄₅H₇₂O₁₆

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 869.06

Ref: 5G-89648

Dioscin

CAS: 19057-60-4

Applications Dioscin, a natural steroid saponin that has been shown to promote anticancer activity against several forms of cancers. Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins.
References Wang, Z., et al.: Land. Biosci., 13, 138 (2012); Shah, H.J., et al.: J. Anal. BIoanal. Tech., 3, 141 (2012); Zhao, X.M., et al.: Toxiciol. Lett., 214, 69 (2012);

Fórmula: C₄₅H₇₂O₁₆

Cor e Forma: Neat

Peso molecular: 869.04

Ref: TR-D485230

Dioscin

CAS: 19057-60-4

Dioscin is a steroidal saponin, which is a naturally occurring compound found in various plants, notably in species such as Dioscorea nipponica and Dioscorea zingiberensis. These plants belong to the yam family, which are well-regarded for their medicinal properties. The mode of action of dioscin involves modulation of various biochemical pathways, including the suppression of inflammatory cytokines and inhibition of cancer cell proliferation. Additionally, dioscin has been shown to promote apoptosis in cancer cells through the activation of caspases and disruption of mitochondrial function.

Fórmula: C₄₅H₇₂O₁₆

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 869.05 g/mol

Ref: 3D-OD11563

Dioscin

CAS: 19057-60-4

Dioscin is a type of steroidal saponin, which is a naturally occurring glycoside. It is primarily derived from various plant sources, including members of the Dioscorea family, such as wild yam species. Dioscin exhibits its biological activity through modulation of multiple molecular pathways, notably exhibiting anti-inflammatory, antioxidative, and antiproliferative effects.

Fórmula: C₄₅H₇₂O₁₆

Pureza: Min. 98.0 Area-%

Peso molecular: 869.04 g/mol

Ref: 3D-Q-100228