CAS 191348-16-0

N-[(9H-Fluoren-9-ilmetoxi)carbonil]-O-[hidroxi(fenilmetoxi)fosfinil]-L-tirosina

Descrição:

N-[(9H-Fluoren-9-ilmetoxi)carbonil]-O-[hidroxi(fenilmetoxi)fosfinil]-L-tirosina, comumente referido pelo seu número CAS 191348-16-0, é um composto sintético que serve como um derivado de fosfonato do aminoácido L-tirosina. Este composto apresenta um grupo protetor de fluorenilmetoxicarbonilo (Fmoc), que é comumente utilizado na síntese de peptídeos para proteger o grupo amino dos aminoácidos. A presença do grupo fosfinilo indica que pode exibir reatividade e atividade biológica únicas, potencialmente influenciando seu papel em vias bioquímicas ou como agente farmacêutico. O substituinte hidroxi(fenilmetoxi) sugere que o composto pode ter solubilidade e estabilidade aprimoradas, tornando-o adequado para várias aplicações em química medicinal. Sua complexidade estrutural permite interações potenciais com alvos biológicos, o que pode ser de interesse no desenvolvimento de medicamentos. No geral, este composto exemplifica a interseção da química orgânica e da bioquímica, destacando a importância dos grupos funcionais na determinação das propriedades e reatividade das substâncias químicas.

Fórmula: C₃₁H₂₈NO₈P

InChI: InChI=1S/C31H28NO8P/c33-30(34)29(18-21-14-16-23(17-15-21)40-41(36,37)39-19-22-8-2-1-3-9-22)32-31(35)38-20-28-26-12-6-4-10-24(26)25-11-5-7-13-27(25)28/h1-17,28-29H,18-20H2,(H,32,35)(H,33,34)(H,36,37)/t29-/m0/s1

Chave InChI: InChIKey=WNFKGEXQEWKECX-LJAQVGFWSA-N

SMILES: C(OC(N[C@@H](CC1=CC=C(OP(OCC2=CC=CC=C2)(=O)O)C=C1)C(O)=O)=O)C3C=4C(C=5C3=CC=CC5)=CC=CC4

Sinónimos:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[4-[hydroxy(phenylmethoxy)phosphoryl]oxyphenyl]propanoic acid
• (2S)-3-[4-(benzyloxy-hydroxy-phosphoryl)oxyphenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
• <span class="text-smallcaps">L</span>-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, phenylmethyl hydrogen phosphate (ester)
• <span class="text-smallcaps">L</span>-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-[hydroxy(phenylmethoxy)phosphinyl]-
• Fmoc-<span class="text-smallcaps">L</span>-O-benzylphosphotyrosine
• Fmoc-L-Tyr(Po(Obzl)Oh)-Oh
• Fmoc-O-Benzylphospho-L-Tyrosine
• Fmoc-Tyr(Ho3Bzl)-Oh
• Fmoc-Tyr(Hpo3Bzl)-Oh
• Fmoc-Tyr(PO(OBzl))-OH
• Fmoc-Tyr[Po(Obz)Oh]-Oh
• Fmoc-Tyrosine(Po(Obzl)Oh)-Oh
• L-Phosphotyrosine
• N-Fmoc-O-benzyl-L-phosphotyrosine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[hydroxy(phenylmethoxy)phosphinyl]-<span class="text-smallcaps">L</span>-tyrosine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[hydroxy(phenylmethoxy)phosphinyl]-L-tyrosine
• L-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, phenylmethyl hydrogen phosphate (ester)
• Fmoc-L-O-benzylphosphotyrosine

Fmoc-Tyr(PO(OBzl)OH)-OH

CAS: 191348-16-0

Alternative to Fmoc-Tyr(PO₃(MDPSE)₂)-OH.

Fórmula: C₃₁H₂₈NO₈P

Pureza: 97.2%

Cor e Forma: White Powder

Peso molecular: 573.54

Ref: 01-4038299

L-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-[hydroxy(phenylmethoxy)phosphinyl]-

CAS: 191348-16-0

Fórmula: C₃₁H₂₈NO₈P

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 573.5297

Ref: IN-DA002F5Y

(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(((benzyloxy)(hydroxy)phosphoryl)oxy)phenyl)propanoic acid

CAS: 191348-16-0

(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(((benzyloxy)(hydroxy)phosphoryl)oxy)phenyl)propanoic acid

Pureza: 97%

Peso molecular: 573.53g/mol

Ref: 54-OR76050

Fmoc-O-benzylphospho-L-tyrosine

CAS: 191348-16-0

Fmoc-O-benzylphospho-L-tyrosine is a synthetic amino acid that can be used as a molecular model for tyrosine kinases. Fmoc-O-benzylphospho-L-tyrosine has been shown to inhibit the activity of tyrosine phosphatases. It also binds to phosphate groups in the presence of calcium ions, which may help to immobilize it and prevent its hydrolysis by phosphatases. The binding constants of Fmoc-O-benzylphospho-L-tyrosine with these phosphate groups are determined using analytical chemistry. Fmoc-O-benzylphospho-L-tyrosine has been found to bind to immobilized cells and be expressed at high levels in mammalian cells.

Fórmula: C₃₁H₂₈NO₈P

Pureza: Min. 97 Area-%

Cor e Forma: White Powder

Peso molecular: 573.53 g/mol

Ref: 3D-FF47780

(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(((benzyloxy)(hydroxy)phosphoryl)oxy)phenyl)propanoic acid

CAS: 191348-16-0

Pureza: 97%

Peso molecular: 573.5380249

Ref: 10-F790976