CAS 19309-14-9

Cardamonina

Descrição:

Cardamonina é um composto que ocorre naturalmente classificado como um chalcona, derivado principalmente das sementes da planta Elettaria cardamomum, comumente conhecida como cardamomo. É caracterizado por sua aparência cristalina amarela e possui uma fórmula molecular que reflete sua estrutura complexa. Cardamonina exibe várias atividades biológicas, incluindo propriedades anti-inflamatórias, antioxidantes e antimicrobianas, tornando-o de interesse na pesquisa farmacológica. Seu mecanismo de ação muitas vezes envolve a modulação de vias de sinalização, que podem influenciar a proliferação celular e a apoptose. Além disso, Cardamonina tem sido estudado por seus potenciais efeitos terapêuticos em condições como câncer e distúrbios metabólicos. O composto é solúvel em solventes orgânicos, mas tem solubilidade limitada em água, o que pode afetar sua biodisponibilidade. No geral, Cardamonina representa uma área significativa de interesse na química de produtos naturais e na pesquisa medicinal devido às suas diversas atividades biológicas e potenciais benefícios à saúde.

Fórmula: C₁₆H₁₄O₄

InChI: InChI=1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+

Chave InChI: InChIKey=NYSZJNUIVUBQMM-BQYQJAHWSA-N

SMILES: C(/C=C/C1=CC=CC=C1)(=O)C2=C(OC)C=C(O)C=C2O

Sinónimos:

• (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one
• (2E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one
• (E)-1-(2,4-Dihydroxy-6-Methoxy-Phenyl)-3-Phenyl-Propenone
• (E)-1-(2,4-Dihydroxy-6-methoxy-phenyl)-3-phenyl-
• 2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-, (2E)-
• 2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-, (E)-
• Alpinetin chalcone
• Cardamomin
• Chalcone, 2', 4'-dihydroxy-6'-methoxy-
• Chalcone, 2′,4′-dihydroxy-6′-methoxy-
• Cardamonin

(E)-Cardamonin

CAS: 19309-14-9

(E)-Cardamonin (Alpinetin chalcone) is a chalconoid that has been isolated from several plants including Alpinia katsumadai and Alpinia conchigera.

Fórmula: C₁₆H₁₄O₄

Pureza: 99.07% - 99.84%

Cor e Forma: Solid

Peso molecular: 270.28

Ref: TM-T2994

Cardamonin

CAS: 19309-14-9

Fórmula: C₁₆H₁₄O₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 270.2800

Ref: IN-DA00AOR0

(E)-1-(2,4-Dihydroxy-6-Methoxyphenyl)-3-Phenylprop-2-En-1-One

CAS: 19309-14-9

(E)-1-(2,4-Dihydroxy-6-Methoxyphenyl)-3-Phenylprop-2-En-1-One

Pureza: 99%

Peso molecular: 270.28g/mol

Ref: 54-OR1008324

(E)-Cardamonin

CAS: 19309-14-9

(E)-Cardamonin

Pureza: ≥98%

Peso molecular: 270.28g/mol

Ref: 54-BUP11154

Cardamonin

CAS: 19309-14-9

Cardamonin is a naturally occurring chalcone with strong anti-inflammatory , anticancer, anti-melanogenesis, and vascular activity. It is a novel TRPA1 antagonist with IC50 of 454 nM and also a NF-kB inhibitor. It ameliorates insulin resistance induced by high insulin and high glucose through the mTOR and signal pathway. It also may be a potential whitening agent for use in cosmetics and in the medical treatment of hyperpigmentation disorders.

Fórmula: C₁₆H₁₄O₄

Pureza: 95%~99%

Peso molecular: 270.284

Ref: BP-BP0315

Cardamonin

CAS: 19309-14-9

Fórmula: C₁₆H₁₄O₄

Pureza: ≥ 98.0%

Cor e Forma: Yellow powder

Peso molecular: 270.28

Ref: 7W-GK9563

Cardamomin

CAS: 19309-14-9

Ketone phenol

Fórmula: C₁₆H₁₄O₄

Pureza: ≥ 98.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 270.29

Ref: 5G-80379

Cardamonin

CAS: 19309-14-9

Cardamonin is a natural chalcone, which is a type of aromatic ketone and an unsaturated polyphenolic compound. It is primarily sourced from various plants, particularly from the seeds of Alpinia katsumadai, a member of the Zingiberaceae family. Its mode of action involves modulation of multiple cellular pathways, including inhibition of NF-κB activation, which plays a critical role in inflammatory responses and cancer cell proliferation. Additionally, cardamonin has been shown to interfere with other signaling pathways like MAPK and PI3K/Akt, which are key in regulating cell growth and survival.

Fórmula: C₁₆H₁₄O₄

Pureza: Min. 95%

Cor e Forma: Yellow Powder

Peso molecular: 270.28 g/mol

Ref: 3D-FC66017

Cardamonin

CAS: 19309-14-9

Applications Cardamonin maintains inhibitory effects of cardamonin on thromboxane A2-induced scratching response in mice. Also inhibits angiotensin II-induced vascular smooth muscle cell proliferation.
References Park, M. et al.: Pharm. Biochem. Behav., 126, 131 (2014); Shen, Y. et al.: J. Nat. Med., 68, 623 (2014);

Fórmula: C₁₆H₁₄O₄

Cor e Forma: Off White Solid

Peso molecular: 270.28

Ref: TR-C183380