CAS 198195-25-4

Trans-3-(4-aminophenyl)acrylate ethyl ester

CAS: 198195-25-4

Trans-3-(4-aminophenyl)acrylate ethyl ester is a supramolecular polymer that has been shown to be effective in the treatment of acute lymphoblastic leukemia. It inhibits spontaneous DNA replication, which may be due to its ability to inhibit the enzymatic activity of the NS5B polymerase and DNA synthesis. Trans-3-(4-aminophenyl)acrylate ethyl ester also has pharmacokinetic properties that make it suitable for oral administration. Trans-3-(4-aminophenyl)acrylate ethyl ester is metabolized by an enzymatic reaction, forming a covalent bond with the damaged DNA strand and thereby preventing further damage to the DNA. This drug can be considered reversible because it can be hydrolyzed by enzymes such as thymidine phosphorylase and thymidine kinase.

Fórmula: C₁₁H₁₃NO₂

Pureza: Min. 95%

Peso molecular: 191.23 g/mol

Ref: 3D-YHA19525