CAS 198561-07-8

FMOC-L-PROPARGILGLICINA

Descrição:

FMOC-L-PROPARGILGLICINA é um composto químico que serve como um bloco de construção na síntese de peptídeos e é particularmente notável por seu papel no desenvolvimento de reações bioortogonais. Apresenta um grupo protetor de fluorenilmetoxicarbonila (FMOC), que é comumente usado para proteger grupos amino durante a síntese de peptídeos, permitindo reações seletivas. O grupo propargílico em sua estrutura introduz uma funcionalidade de alquino, permitindo que participe da química de cliques, particularmente com azidas, facilitando a formação de ligações triazólicas estáveis. Este composto é tipicamente utilizado em pesquisas e aplicações farmacêuticas, especialmente na síntese de peptídeos que requerem modificações ou funcionalizações específicas. Sua estabilidade sob condições laboratoriais padrão o torna um reagente valioso na síntese orgânica. Além disso, FMOC-L-PROPARGILGLICINA é caracterizado por sua solubilidade em solventes orgânicos, o que é vantajoso para vários procedimentos sintéticos. Assim como com todas as substâncias químicas, devem ser observadas as precauções adequadas de manuseio e segurança devido aos perigos potenciais associados ao seu uso.

Fórmula: C₂₀H₁₇NO₄

InChI: InChI=1/C20H17NO4/c1-2-7-18(19(22)23)21-20(24)25-12-17-15-10-5-3-8-13(15)14-9-4-6-11-16(14)17/h1,3-6,8-11,17-18H,7,12H2,(H,21,24)(H,22,23)/t18-/m1/s1

Chave InChI: InChIKey=DJGMNCKHNMRKFM-SFHVURJKSA-N

SMILES: C(OC(N[C@@H](CC#C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinónimos:

• (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}pent-4-ynoic acid
• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)pent-4-ynoic acid
• (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-pentynoic acid
• (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}pent-4-ynoic acid
• (S)-2-(Fmoc-Amino)-4-Pentynoic Acid
• 4-Pentynoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)-
• 4-Pentynoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (S)-
• Fmoc-(S)-2-Propargylglycine
• Fmoc-<span class="text-smallcaps">L</span>-propargylglycine
• Fmoc-Pra-Oh
• N-Alpha-(9-Fluorenylmethoxycarbonyl)-(S)-2-Amino-4-Pentynoic Acid
• N-Alpha-(9-Fluorenylmethoxycarbonyl)-Propargylglycine
• N-Alpha-(9-Fluorenylmethyloxycarbonyl)-L-Propargylglycine
• Rarechem Bk Pt 0257
• Fmoc-L-propargylglycine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-propargylglycine&gt
• FMOC-L-PROPARGYL-GLY-OH
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-propargylglycine
• (S)-N-FMoc-2-(2'-propynyl)glycine
• (S)-2-(Fmoc-amino)-4-pentynoic acid, Fmoc-L-2-propargylglycine
• Fmoc-Pra-OH Fmoc-Propargylglycine
• N-Fmoc-L-propargylglycine,95%
• (S)-N-(9-FLUORENYLMETHOXYCARBONYL)-2-AMINO-4-PENTYNOIC ACID
• FMOC-GLY(PROPARGYL)-OH
• Fmoc-L-propargylglycine Novabiochem
• Fmoc-L-propargylglycine≥ 99% (HPLC, Chiral purity)
• N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-propargylglycine, (S)-2-(Fmoc-amino)-4-pentynoic acid
• (S)-N-FMOC-PROPARGYLGLYCINE
• 4-Pentynoicacid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)-
• N-FMoc-L-propargylglycine, 95%
• N-Fluorenemethoxycarbonyl-L-Propargyl Glycine
• L-2-Propargylglycine, N-FMOC protected
• (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)pent-4-ynoic acid
• FMOC-L-2-PROPARGYLGLYCINE
• FMoc-Propargyl-Gly-OH, (S)-2-(FMoc-aMino)-4-pentynoic acid
• FMOC-L-PRA-OH
• (S)-N-FMOC-Propargylglycine, 98% ee, 95%
• Fmoc-propargyl-Gly-OH
• (S)-2-(Fmoc-amino)-4-pentynoic
• (9H-Fluoren-9-yl)MethOxy]Carbonyl Pra-OH
• Fmoc-Pra-OH（Fmoc-Propargly-Gly-OH）
• (S)-N-fmoc-Propargylglycine(e.e.)

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-propargylglycine

CAS: 198561-07-8

Fórmula: C₂₀H₁₇NO₄

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 335.36

Ref: 3B-F0926

N-Fmoc-L-propargylglycine, 95%

CAS: 198561-07-8

Fmoc-propargyl-Gly-OH is an Fmoc protected glycine derivative useful for solid phase peptide synthesis techniques. This compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function. N-Fmoc-L-propargylglycine is a non-natural amino acids used

Fórmula: C₂₀H₁₇NO₄

Pureza: 95%

Cor e Forma: White, Powder

Peso molecular: 335.36

Ref: 02-H52171

Fmoc-L-propargylglycine

CAS: 198561-07-8

Fórmula: C₂₀H₁₇NO₄

Pureza: 97%

Cor e Forma: Solid, Crystalline Powder or Powder

Peso molecular: 335.359

Ref: 10-F492822

Fmoc-Pra-OH

CAS: 198561-07-8

Building block for the synthesis of precursor peptides for tritiation, and for “click chemistry”. Pra-containing peptides have been modified by 1,3-dipolar cycloaddition, e.g. with alkyl azides. Peptides containing a Pra residue and an α-azido acid have been cyclized in the presence of CuBr/Na-ascorbate via triazole formation. Educt for the synthesis of Phe-derivatives by rhodium-catalyzed [2+2+2] cycloaddition.

Fórmula: C₂₀H₁₇NO₄

Pureza: 99.9%

Cor e Forma: White

Peso molecular: 335.36

Ref: 01-4053914

4-Pentynoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)-

CAS: 198561-07-8

Fórmula: C₂₀H₁₇NO₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 335.3533

Ref: IN-DA002BML

Fmoc-propargyl-Gly-OH

CAS: 198561-07-8

Fórmula: C₂₀H₁₇NO₄

Pureza: ≥ 98.0%

Cor e Forma: White to almost white powder or crystals

Peso molecular: 335.36

Ref: 7W-GM4391

L-2-Propargylglycine, N-FMOC protected

CAS: 198561-07-8

L-2-Propargylglycine, N-FMOC protected

Fórmula: C₂₀H₁₇NO₄

Pureza: 98%

Cor e Forma: off-white solid

Peso molecular: 335.35328g/mol

Ref: 54-OR14676

Fmoc-Pra-OH

CAS: 198561-07-8

Fmoc-Pra-OH is a bioconjugate used in Click Chemistry. Click Chemistry is a chemical reaction that joins two components together by forming an amide bond between the carboxyl group of one component and the amino group on the other component. Fmoc-Pra-OH was synthesized by reacting the epidermal growth factor (EGF) with a cyclic peptide containing an acid moiety, which was conjugated to the azide group of an azidopropargyl linker. This bioconjugate has been shown to have proliferative activity in vitro and structural studies have been performed to understand its reactivity.

Fórmula: C₂₀H₁₇NO₄

Pureza: Min. 98.0 Area-%

Peso molecular: 335.36 g/mol

Ref: 3D-PRA-5010-PI

Fmoc-L-propargylglycine

CAS: 198561-07-8

Fmoc-L-propargylglycine is a cyclic peptide that is synthesized by chemical ligation. It has antiviral, anti-tumor, and anti-inflammatory activities. Fmoc-L-propargylglycine inhibits the growth of cancer cells in vitro. The mechanism of action is not fully understood, but it may involve the inhibition of cellular proliferation and the induction of apoptosis. This compound also inhibits epidermal growth factor (EGF) induced cell proliferation in caco-2 cells.

Fórmula: C₂₀H₁₇NO₄

Pureza: Min. 98 Area-%

Cor e Forma: White Powder

Peso molecular: 335.35 g/mol

Ref: 3D-FF40126

Fmoc-l-propargylglycine

Produto Controlado

CAS: 198561-07-8

Applications Fmoc-l-propargylglycine has been used to study the bioorthogonal chemical tagging of protein cholesterylation in living cells.
References William P. H., et al., ChemComm., 47, 4081-4083 (2011)

Fórmula: C₂₀H₁₇NO₄

Cor e Forma: Neat

Peso molecular: 335.35

Ref: TR-F861030