CAS 2002-44-0

L-Prolil-L-leucilglicinamida

Descrição:

L-Prolil-L-leucilglicinamida, com o número CAS 2002-44-0, é um peptídeo sintético que consiste em três aminoácidos: prolina, leucina e glicina. Este composto é caracterizado por sua sequência específica, que influencia sua atividade biológica e interações. Peptídeos como L-Prolil-L-leucilglicinamida são frequentemente estudados por seus papéis potenciais em vários processos fisiológicos, incluindo seus efeitos na neurotransmissão e regulação hormonal. A presença de prolina em sua estrutura pode contribuir para propriedades conformacionais únicas, potencialmente afetando sua estabilidade e solubilidade. Além disso, a natureza hidrofóbica da leucina pode influenciar suas interações com membranas biológicas ou proteínas. L-Prolil-L-leucilglicinamida também pode exibir afinidades de ligação específicas a receptores, tornando-o de interesse na pesquisa farmacológica. No geral, as características deste composto, incluindo sua composição de aminoácidos e sequência, desempenham um papel crucial na determinação de sua funcionalidade e potenciais aplicações em bioquímica e química medicinal.

Fórmula: C₁₃H₂₄N₄O₃

InChI: InChI=1/C13H24N4O3/c1-8(2)6-10(12(19)16-7-11(14)18)17-13(20)9-4-3-5-15-9/h8-10,15H,3-7H2,1-2H3,(H2,14,18)(H,16,19)(H,17,20)/t9-,10-/m0/s1

Chave InChI: InChIKey=NOOJLZTTWSNHOX-UWVGGRQHSA-N

SMILES: [C@@H](NC(=O)[C@@H]1CCCN1)(C(NCC(N)=O)=O)CC(C)C

Sinónimos:

• 2-Pyrrolidinecarboxamide, N-[1-[(carbamoylmethyl)carbamoyl]-3-methylbutyl]-
• 26: PN: US6093797 PAGE: 15 claimed protein
• 27: PN: US6093797 PAGE: 15 claimed protein
• 2: PN: WO2009039992 PAGE: 107 claimed protein
• 7-9-Oxytocin
• <span class="text-smallcaps">L</smallcap>-Proline-<smallcap>L</span>-leucine-glycine-amide
• <span class="text-smallcaps">L</smallcap>-Prolyl-<smallcap>L</span>-leucyl-glycine amide
• <span class="text-smallcaps">L</smallcap>-Prolyl-<smallcap>L</span>-leucylglycinamide
• <span class="text-smallcaps">L</smallcap>-Prolyl-<smallcap>L</span>-leucylglycylamide
• Glycinamide, <span class="text-smallcaps">L</smallcap>-prolyl-<smallcap>L</span>-leucyl-
• H-Pro-Leu-Gly-NH2
• H-Pro-Leu-Gly-NH₂
• L-Prolyl-L-leucylglycinamide, hemihydrate
• L-prolyl-L-leucylglycinamide
• MSH-release inhibiting factor I
• Melanocyte-Stimulating Hormone-Release Inhibiting Factor
• Melanocyte-stimulating hormone release-inhibiting factor 1
• Melanocyte-stimulating hormone release-inhibiting factor I
• Melanocyte-stimulating hormone release-inhibiting factor I (ox)
• Melanostatin I (ox)
• Mif-1
• Mif-I
• Oxytocin C-terminal tripeptide
• Pro-Leu-Gly-NH₂
• Prolyleucyl-glycinamide
• Prolylleucylglycine amide
• Pro-Leu-Gly-NH2
• Glycinamide, L-prolyl-L-leucyl-
• L-Proline-L-leucine-glycine-amide
• Melanocyte-stimulati
• (2S)-N-[(1S)-1-[(2-amino-2-keto-ethyl)carbamoyl]-3-methyl-butyl]pyrrolidine-2-carboxamide
• Melanostatin, MIF-I, Oxytocin fragment 7-9
• MIF, AMIDE
• MELANOCYTE STIMULATING HORMONE RELEASE INHIBITING FACTOR, AMIDE
• (2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
• MSH RELEASE INHIBITING FACTOR, AMIDE
• MELANOCYTE STIMULATING HORMONE RELEASING FACTOR
• PLG-NH2
• (2S)-N-[(2S)-1-[(2-azanyl-2-oxo-ethyl)amino]-4-methyl-1-oxo-pentan-2-yl]pyrrolidine-2-carboxamide
• PRO-LEU-GLY AMIDE;MIF-I;OXYTOCIN FRAGMENT 7-9
• MSH-RELEASE INHIBITING FACTOR
• MELANOSTATIN
• (S)-N-((S)-1-((2-Amino-2-oxoethyl)amino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
• MSH-R-IF
• Melanostatin I
• MIF-I, Melanostatin, Melanotropin Release-Inhibiting Factor
• PRO-LEU-GLY AMIDE

Melanocyte-Stimulating Hormone-Release Inhibiting Factor

CAS: 2002-44-0

MIF-I, the C-terminal tripeptide of oxytocin, has been shown to be active in numerous behavioral tests and clinical situations.

Fórmula: C₁₃H₂₄N₄O₃

Pureza: > 99%

Cor e Forma: White

Peso molecular: 284.36

Ref: 01-4000343

H-PRO-LEU-GLY-NH2

CAS: 2002-44-0

Fórmula: C₁₃H₂₄N₄O₃

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 284.3547

Ref: IN-DA00BCS5

(S)-N-((S)-1-((2-Amino-2-oxoethyl)amino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide

CAS: 2002-44-0

Fórmula: C₁₃H₂₄N₄O₃

Pureza: 95.0%

Peso molecular: 284.36

Ref: 10-F242063

MSH-Release Inhibiting Factor

CAS: 2002-44-0

MSH-Release Inhibiting Factor (MRIF) has been shown to be a potent inhibitor of the release of proinflammatory cytokines. It is derived from the acid methyl ester of mouse serum, and has been shown to inhibit the release of tumor necrosis factor-α (TNF-α) in animal studies. MRIF has also been shown to have anti-diabetic effects in mice. MRIF inhibits the production of inflammatory cytokines by blocking TNF-α at a molecular level. This protein binds to progesterone receptor and prevents it from interacting with its ligand, which is necessary for cancer cell growth. The expression system for this protein is E. coli, and it can be used as an immunosuppressant in animal studies.
MRIF also blocks TNF-α activity by inhibiting transcriptional activation of NFκB and AP-1, which are proteins that regulate gene expression.

Fórmula: C₁₃H₂₄N₄O₃H₂O

Pureza: Min. 95%

Peso molecular: 293.36 g/mol

Ref: 3D-PMI-4024

Melanocyte-Stimulating Hormone-Release Inhibiting Factor

CAS: 2002-44-0

Melanocyte-Stimulating Hormone-Release Inhibiting Factor (MSH-RF) is a synthetic peptide that inhibits the release of melanin from melanocytes. MSH-RF has been shown to be a useful treatment for melatonin deficiency, which may be related to immune system disorders such as infectious diseases and autoimmune diseases. It has also been shown to have significant interactions with other hormones such as dopamine, affecting locomotor activity and the ph optimum, among other biological properties. The structure of MSH-RF has been determined using X-ray crystallography on an amide bond. This peptide hormone is found in human serum and is involved in regulating camp levels.

Fórmula: C₁₃H₂₄N₄O₃

Pureza: Min. 95%

Peso molecular: 284.35 g/mol

Ref: 3D-FM109235