CAS 200940-22-3

2,3-Diidro-5-metil-N-[6-[(2-metil-3-piridinil)oxi]-3-piridinil]-6-(trifluorometil)-1H-indol-1-carboxamida

Descrição:

2,3-Diidro-5-metil-N-[6-[(2-metil-3-piridinil)oxi]-3-piridinil]-6-(trifluorometil)-1H-indol-1-carboxamida, com número CAS 200940-22-3, é um composto orgânico sintético caracterizado por sua complexa estrutura molecular, que inclui um núcleo de indol, múltiplos anéis aromáticos e vários grupos funcionais, como trifluorometila e carboxamida. Este composto exibe propriedades típicas dos derivados do indol, incluindo potencial atividade biológica, tornando-o de interesse na pesquisa farmacêutica. A presença de anéis de piridina sugere possíveis interações com alvos biológicos, potencialmente influenciando sua farmacocinética e farmacodinâmica. Além disso, sabe-se que o grupo trifluorometila melhora a lipofilicidade e a estabilidade metabólica, o que pode ser vantajoso no design de medicamentos. A solubilidade, estabilidade e reatividade do composto dependeriam de seus grupos funcionais específicos e da conformação molecular geral. Assim como muitas moléculas orgânicas complexas, sua síntese e caracterização exigiriam técnicas avançadas, como espectroscopia de RMN, espectrometria de massas e cristalografia para confirmar sua estrutura e pureza.

Fórmula: C₂₂H₁₉F₃N₄O₂

InChI: InChI=1S/C22H19F3N4O2/c1-13-10-15-7-9-29(18(15)11-17(13)22(23,24)25)21(30)28-16-5-6-20(27-12-16)31-19-4-3-8-26-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,28,30)

Chave InChI: InChIKey=ZETBBVYSBABLHL-UHFFFAOYSA-N

SMILES: C(NC=1C=CC(OC2=C(C)N=CC=C2)=NC1)(=O)N3C=4C(=CC(C)=C(C(F)(F)F)C4)CC3

Sinónimos:

• 1H-Indole-1-carboxamide, 2,3-dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-6-(trifluoromethyl)-
• 2,3-Dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-6-(trifluoromethyl)-1H-indole-1-carboxamide
• Sb-243213

SB 243213

CAS: 200940-22-3

SB 243213

Pureza: ≥98%

Peso molecular: 428.41g/mol

Ref: 54-BUP07457

SB 243213

CAS: 200940-22-3

SB 243213 is a 5-HT2C receptor antagonist with anxiolytic and antidepressant activity used in schizophrenia and movement disorders.

Fórmula: C₂₂H₁₉F₃N₄O₂

Pureza: 98.78% - 99.86%

Cor e Forma: Solid

Peso molecular: 428.41

Ref: TM-T37816

SB 243213

CAS: 200940-22-3

SB 243213 is a compound that has been extensively studied for its effects on melanogenesis and pigmentation. It acts as an antagonist for the IL-1 receptor, specifically IL-1RA, and the 5-HT2C receptor in humans. This compound has potential applications in the diagnosis and treatment of conditions related to pigmentation disorders such as vitiligo and melasma. Additionally, SB 243213 has shown promising results in cancer research, particularly as an inhibitory factor for melanoma cells. It can also be used in the development of microcapsules for targeted drug delivery in diseases like diabetes. Although not a fluoroquinolone or steroidal compound itself, SB 243213 belongs to the class of research chemicals that have gained attention in various scientific fields.

Fórmula: C₂₂H₁₉F₃N₄O₂

Pureza: Min. 95%

Peso molecular: 428.4 g/mol

Ref: 3D-AIA94022

SB 243213

CAS: 200940-22-3

SB 243213 is a cell-permeable, potent, and selective inhibitor of the Kv1.3 potassium channel that is used as a research tool in pharmacology and cell biology. SB 243213 is a peptide that binds to the receptor site on the Kv1.3 channel and blocks ion flow, thereby inhibiting this type of potassium channel. The binding affinity of SB 243213 to the Kv1.3 receptor site is greater than 10,000 times higher than its binding affinity for other ion channels such as the nicotinic acetylcholine receptors. This agent has been shown to be an activator of protein interactions in cells and has also been used as an antibody labeling reagent.

Fórmula: C₂₂H₁₉F₃N₄O₂

Pureza: Min. 95%

Peso molecular: 428.4 g/mol

Ref: 3D-BS181806