CAS 2022-85-7

Flucitosina

Descrição:

Flucitosina, com o número CAS 2022-85-7, é um medicamento antifúngico utilizado principalmente para tratar infecções fúngicas graves, particularmente aquelas causadas por espécies de Candida e Cryptococcus. É um análogo de pirimidina que interfere na síntese de ácidos nucleicos ao inibir a timidilato sintase, interrompendo, em última análise, a síntese de DNA e RNA fúngico. Flucitosina é tipicamente administrado em conjunto com outros agentes antifúngicos, como a anfotericina B, para aumentar sua eficácia e reduzir o risco de resistência. A substância é bem absorvida quando tomada por via oral e é amplamente distribuída pelo corpo, incluindo o sistema nervoso central, tornando-a eficaz no tratamento da meningite criptocócica. Flucitosina geralmente é bem tolerado, mas pode causar efeitos colaterais como supressão da medula óssea e distúrbios gastrointestinais. Seu uso requer monitoramento cuidadoso da função renal e das contagens sanguíneas devido à potencial toxicidade. No geral, Flucitosina é uma ferramenta valiosa no arsenal antifúngico, particularmente para pacientes imunocomprometidos.

Fórmula: C₄H₄FN₃O

InChI: InChI=1/C4H4FN3O/c5-8-2-1-3(6)7-4(8)9/h1-2H,(H2,6,7,9)

Chave InChI: InChIKey=XRECTZIEBJDKEO-UHFFFAOYSA-N

SMILES: NC1=C(F)C=NC(=O)N1

Sinónimos:

• 2(1H)-Pyrimidinone, 4-amino-5-fluoro-
• 2(1H)-Pyrimidinone, 6-amino-5-fluoro-
• 2-Hydroxy-4-Amino-5-Fluoropyrimidine
• 4-Amino-5-Fluoro-2(1H)-Pyrimidinone
• 4-Amino-5-fluoro-2(1H)-pyrmidinone
• 4-Amino-5-fluoropyrimidin-2(1H)-one
• 4-Amino-5-fluoropyrimidin-2-ol
• 4-amino-1-fluoropyrimidin-2(1H)-one
• 5-Flucytosine
• 5-Fluoro Cytosine
• 5-Fluorocystosine
• 5-Fluorocytosin
• 5-Fluorocytosine
• 6-Amino-2-oxo-5-fluoropyrimidine
• 6-Amino-5-fluoro-2(1H)-pyrimidinone
• 6-amino-5-fluoropyrimidin-2(1H)-one
• Alcobon
• Ancobon
• Ancotil
• Ancotyl
• Cytosine, 5-fluoro-
• Flucitosina
• Flucylosine
• Flucytosin
• Flucytosine
• Fluocytosine
• Nsc 103805
• Ro 2-9915
• Toca FC
• 5-FC
• TIMTEC-BB SBB000061
• 4-AMINO-5-FLUORO-3H-PYRIMIDIN-2-ONE
• FLUCYSTINE
• fluorocytosine
• 4-amino-5-fluoro-2(1h)-pyrimidinon
• 4-AMINO-5-FLUORO-2(1H)-PYRIMIDINE

5-Fluorocytosine

CAS: 2022-85-7

Fórmula: C₄H₄FN₃O

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 129.09

Ref: 3B-F0321

5-Fluorocytosine, 98+%

CAS: 2022-85-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₄H₄FN₃O

Pureza: 98+%

Cor e Forma: White, crystalline powder

Peso molecular: 129.09

Ref: 02-L16496

Flucytosine 2.0 mg/ml in Methanol

CAS: 2022-85-7

Cor e Forma: Single Solution

Ref: 61-AMP0355.00-07

Flucytosine

CAS: 2022-85-7

Cor e Forma: Neat

Ref: 61-FOR0355.00

FLUCYTOSINE RS

CAS: 2022-85-7

FLUCYTOSINE RS

Fórmula: C₄H₄FN₃O

Peso molecular: 129.0925

Ref: 41-ICRS0310

FLUCYTOSINE FOR SYSTEM SUITABILITY CRS

CAS: 2022-85-7

FLUCYTOSINE FOR SYSTEM SUITABILITY CRS

Fórmula: C₄H₄FN₃O

Peso molecular: 129.0925

Ref: 41-Y0001262

FLUCYTOSINE CRS

CAS: 2022-85-7

FLUCYTOSINE CRS

Fórmula: C₄H₄FN₃O

Cor e Forma: Crystalline Powder. White. Powder.

Peso molecular: 129.0925

Ref: 41-F0175000

Flucytosine

CAS: 2022-85-7

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Fórmula: C₄H₄FN₃O

Cor e Forma: White Off-White Crystalline Powder

Peso molecular: 129.03384

Ref: 45-1272000

2(1H)-Pyrimidinone, 6-amino-5-fluoro-

CAS: 2022-85-7

Fórmula: C₄H₄FN₃O

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 129.0925

Ref: IN-DA002851

Flucytosine

CAS: 2022-85-7

Flucytosine (NSC 103805) is a pyrimidine compound and a fluorinated cytosine analog exhibiting antifungal activity.

Fórmula: C₄H₄FN₃O

Pureza: 98.76% - 99.28%

Cor e Forma: White Crystalline Solid Solid

Peso molecular: 129.09

Ref: TM-T0986

5-Fluorocytosine

CAS: 2022-85-7

Fórmula: C₄H₄FN₃O

Pureza: ≥ 98.0%

Cor e Forma: White to off-white crystalline powder

Peso molecular: 129.09

Ref: 7W-GA6771

Flucytosine

CAS: 2022-85-7

Flucytosine

Pureza: ≥98%

Peso molecular: 129.09g/mol

Ref: 54-BUP19221

5-Fluorocytosine

CAS: 2022-85-7

5-Fluorocytosine

Fórmula: C₄H₄FN₃O

Pureza: 97%

Cor e Forma: off white powder

Peso molecular: 129.09g/mol

Ref: 54-PC3735

Flucytosine

CAS: 2022-85-7

Fórmula: C₄H₄FN₃O

Peso molecular: 129.09

Ref: 4Z-F-422

5-Fluorocytosine

CAS: 2022-85-7

Pureza: 97%

Peso molecular: 129.09

Ref: FT-F14483

Flucytosine

CAS: 2022-85-7

Fórmula: C₄H₄FN₃O

Cor e Forma: Neat

Peso molecular: 129.09

Ref: 86-MM0355.00

Flucytosine

CAS: 2022-85-7

Cor e Forma: Neat

Ref: 04-C13700500

5-Fluoro Cytosine

Produto Controlado

CAS: 2022-85-7

Applications 5-FC is a toxic antifungal/antimicrobial agent.
References Gopinath, P., et al.: Biotechnol. Lett., 30, 1913 (2008), Kalkanci, A., et al.: Microbiol Immunol., 52, 435 (2008), Dubeau, M., et al.: App. Env. Microbiol., 75, 1211 (2009),

Fórmula: C₄H₄FN₃O

Cor e Forma: White To Off-White

Peso molecular: 129.09

Ref: TR-F589000

Cytosine-13C,15N2

CAS: 2022-85-7

Fórmula: CC₃H₅₁₅N₂NO

Cor e Forma: Off-White To Light Yellow

Peso molecular: 114.08

Ref: TR-C998952

5-Fluorocytosine

CAS: 2022-85-7

Flucytosine is an antifungal agent that inhibits the synthesis of DNA by preventing the conversion of deoxyuridine monophosphate to uracil monophosphate. It is used as an antiretroviral therapy in combination with other drugs, such as zidovudine and dideoxyinosine, to treat HIV infections. Flucytosine has been shown to have a strong antitumor response in a model system involving mice with sarcoma 180. This drug can cause serious side effects, including drug interactions and resistance mutations in microorganisms. These side effects are often observed in patients undergoing cancer chemotherapy or immunosuppressive therapy.

Fórmula: C₄H₄FN₃O

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 129.09 g/mol

Ref: 3D-FF02813