CAS 20554-84-1

(-)-Parthenolida

Descrição:

(-)-Parthenolida é uma lactona sesquiterpênica derivada principalmente da planta Tanacetum parthenium, comumente conhecida como matricária. Este composto é caracterizado por sua estrutura bicíclica única, que inclui um grupo funcional lactona. (-)-Parthenolida exibe uma variedade de atividades biológicas, incluindo propriedades anti-inflamatórias, anticancerígenas e antimicrobianas, tornando-se um assunto de interesse na pesquisa farmacológica. Sabe-se que inibe a via de sinalização do fator nuclear kappa B (NF-κB), que desempenha um papel crucial na inflamação e na progressão do câncer. O composto é tipicamente encontrado em forma líquida incolor a amarelo pálido e tem um odor característico. Sua solubilidade varia, sendo mais solúvel em solventes orgânicos do que em água. Devido aos seus potenciais efeitos terapêuticos, (-)-Parthenolida está sendo estudado por seu papel no tratamento de várias condições, incluindo enxaquecas e certos tipos de câncer. No entanto, mais pesquisas são necessárias para entender completamente seus mecanismos de ação e aplicações potenciais na medicina.

Fórmula: C₁₅H₂₀O₃

InChI: InChI=1/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5+/t11?,12-,13-,15+/m0/s1

Chave InChI: InChIKey=KTEXNACQROZXEV-PVLRGYAZSA-N

SMILES: C[C@]12[C@@]([C@@]3([C@](C(=C)C(=O)O3)(CC\C(\C)=C\CC1)[H])[H])(O2)[H]

Sinónimos:

• (1aR,4E,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• (1aR,4E,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• (1aR,4E,7aS,10aS,10bR)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• (1aR,4Z,7aS,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• (1aR,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• (4E,7aS,10aS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• (4Z)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• 2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno(9,10)cyclodeca(1,2-b)furan-9(1aH)-one
• Germacra-1(10),11(13)-dien-12-oic acid, 4,5α-epoxy-6β-hydroxy-, γ-lactone
• Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bR)-
• Parthenolide

Parthenolide

CAS: 20554-84-1

Parthenolide analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₁₅H₂₀O₃

Pureza: (HPLC) ≥95%

Cor e Forma: Powder

Peso molecular: 248.33

Ref: 11-3805

PARTHENOLIDE CRS

CAS: 20554-84-1

PARTHENOLIDE CRS

Ref: 41-Y0001838

Parthenolide

CAS: 20554-84-1

Lactones, nesoi

Fórmula: C₁₅H₂₀O₃

Cor e Forma: White Crystalline Powder

Peso molecular: 248.14124

Ref: 45-1500400

Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bR)-

CAS: 20554-84-1

Fórmula: C₁₅H₂₀O₃

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 248.3175

Ref: IN-DA002A6V

Parthenolide

CAS: 20554-84-1

Fórmula: C₁₅H₂₀O₃

Pureza: ≥ 98.0%

Cor e Forma: White, off-white or pale yellow-brown powder

Peso molecular: 248.32

Ref: 7W-GP2300

Parthenolide

CAS: 20554-84-1

Parthenolide

Fórmula: C₁₅H₂₀O₃

Pureza: By hplc: 99.88% (Typical Value in Batch COA)

Cor e Forma: white crystals

Peso molecular: 248.32g/mol

Ref: 54-BIP0110

Parthenolide

CAS: 20554-84-1

Parthenolide

Pureza: ≥98%

Peso molecular: 248.32g/mol

Ref: 54-BUP15119

Parthenolide

CAS: 20554-84-1

Fórmula: C₁₅H₂₀O₃

Pureza: 95%~99%

Peso molecular: 248.322

Ref: BP-BP1066

Parthenolide

CAS: 20554-84-1

Fórmula: C₁₅H₂₀O₃

Pureza: >97.0%(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 248.32

Ref: 3B-P1982

Parthenolide

CAS: 20554-84-1

Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.

Fórmula: C₁₅H₂₀O₃

Pureza: 98.19% - 99.46%

Cor e Forma: White To Pale Yellow Crystalline Powder

Peso molecular: 248.32

Ref: TM-T2140

Parthenolide

CAS: 20554-84-1

Lactone

Fórmula: C₁₅H₂₀O₃

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 248.32

Ref: 5G-89255

Parthenolide

CAS: 20554-84-1

Parthenolide is a sesquiterpene lactone, which is a bioactive compound derived from the plant species Tanacetum parthenium, commonly known as feverfew. This compound is primarily isolated from the aerial parts of the plant, where it is found in highest concentrations within the flowers and leaves. Parthenolide exerts its effects through several biochemical pathways, including the inhibition of nuclear factor-kappa B (NF-κB) signaling, which plays a critical role in inflammatory and immune responses. Additionally, it disrupts the activity of certain kinases and modulates the expression of genes involved in cell cycle regulation and apoptosis.

Fórmula: C₁₅H₂₀O₃

Pureza: Min. 98 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 248.32 g/mol

Ref: 3D-FP65646

Parthenolide

CAS: 20554-84-1

M02322 - Parthenolide

Fórmula: C₁₅H₂₀O₃

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 248.322

Ref: 10-M02322