CAS 2064292-12-0

(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-N-(4-((1-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2-oxo-6,9,12-trioxa-3-azatetradecan-14-yl)carbamoyl)-2-methoxyphenyl)-4-cyano-

CAS: 2064292-12-0

Fórmula: C₅₈H₆₂Cl₃F₂N₉O₇S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1173.5898

Ref: IN-DA01K2SL

A1874

CAS: 2064292-12-0

A1874

Pureza: ≥95%

Peso molecular: 1173.59g/mol

Ref: 54-BUP02026

A1874

CAS: 2064292-12-0

A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. Effective in inhibiting many cancer cell lines proliferation.

Fórmula: C₅₈H₆₂Cl₃F₂N₉O₇S

Pureza: 99.52%

Cor e Forma: Solid

Peso molecular: 1173.59

Ref: TM-T5442

A1874

Produto Controlado

CAS: 2064292-12-0

A1874 is a bifunctional inhibitor of the E3 ubiquitin ligases, which are enzymes that tag proteins for degradation by the proteasome. It has been shown to be effective in inhibiting autophagy, and thus stabilizing protein levels. A1874 has also been shown to cause cell death in cancer cells and inhibit tumor growth in animals. This agent is a reactive agent that can cause DNA damage and induce tumor-specific apoptosis. The oxadiazole moiety is responsible for its cytotoxic properties.

Fórmula: C₅₈H₆₂Cl₃F₂N₉O₇S

Pureza: Min. 95%

Peso molecular: 1,173.59 g/mol

Ref: 3D-PHD29212