CAS 2093391-24-1

HJB97

CAS: 2093391-24-1

HJB97 is a heterobifunctional molecule that can be used in the development of new pharmaceuticals. It has been shown to inhibit cancer and inflammatory diseases. HJB97 is able to bind to ubiquitin, inhibiting the ubiquitination and proteasomal degradation of its target protein. HJB97 also has the ability to interact with bromodomains, inhibiting the transcriptional activity of these proteins. This dual-action makes HJB97 a potential anticancer agent as it inhibits cancer by preventing ternary complex formation and by inhibition of inflammatory disease through inhibition of stepwise activation.

Fórmula: C₂₆H₂₈N₈O₃

Pureza: Min. 95%

Peso molecular: 500.6 g/mol

Ref: 3D-TID39124

HJB97

CAS: 2093391-24-1

HJB97 is used for the design of potential PROTAC BET degrader. It also has antitumor activity. HJB97 is a high-affinity inhibitor of BET (Kis: 0.9 nM (BRD2 BD1), 0.27 nM (BRD2 BD2), 0.18 nM (BRD3 BD1), 0.21 nM (BRD3 BD2), 0.5 nM (BRD4 BD1), 1.0 nM (BRD4 BD2), respectively).

Fórmula: C₂₆H₂₈N₈O₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 500.55

Ref: TM-T15484