CAS: 209984-57-6 - (αS)-N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-α-hydroxybenzeneacetamide

Fórmula: C₂₆H₂₃F₂N₃O₄

InChI: InChI=1S/C26H23F2N3O4/c1-14(29-25(34)23(32)15-11-16(27)13-17(28)12-15)24(33)30-22-20-9-4-3-7-18(20)19-8-5-6-10-21(19)31(2)26(22)35/h3-14,22-23,32H,1-2H3,(H,29,34)(H,30,33)/t14-,22-,23-/m0/s1

Chave InChI: InChIKey=ULSSJYNJIZWPSB-CVRXJBIPSA-N

SMILES: O=C(NC(C(=O)NC1C(=O)N(C=2C=CC=CC2C=3C=CC=CC31)C)C)C(O)C=4C=C(F)C=C(F)C4

Sinónimos:

• (αS)-N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-α-hydroxybenzeneacetamide
• Ly 411,575
• Ly411575
• Benzeneacetamide, N-[(1S)-2-[[(7S)-6,7-dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-α-hydroxy-, (αS)-

Benzeneacetamide, N-[(1S)-2-[[(7S)-6,7-dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-α-hydroxy-, (αS)-

CAS: 209984-57-6

• Fórmula: C₂₆H₂₃F₂N₃O₄
• Pureza: 98%
• Cor e Forma: Solid
• Peso molecular: 479.4753

LY-411575

CAS: 209984-57-6

• Fórmula: C₂₆H₂₃F₂N₃O₄
• Pureza: >95.0%(HPLC)(qNMR)
• Cor e Forma: White to Light yellow powder to crystal
• Peso molecular: 479.48

LY-411575

CAS: 209984-57-6

LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and …

• Fórmula: C₂₆H₂₃F₂N₃O₄
• Pureza: 97.03% - 99.38%
• Cor e Forma: Solid
• Peso molecular: 479.48

LY 411575

CAS: 209984-57-6

Potent inhibitor of γ-secretase. LY 411575 inhibited production of amyloid β (Aβ) peptides with IC50 …

• Fórmula: C₂₆H₂₃F₂N₃O₄
• Pureza: Min. 95%
• Cor e Forma: Solid
• Peso molecular: 479.48 g/mol