CAS 21085-72-3

Acetobromo-α-D-ácido glucurônico éster metílico

Descrição:

Acetobromo-α-D-ácido glucurônico éster metílico é um composto químico que pertence à classe dos derivados do ácido glucurônico. É caracterizado pela presença de um átomo de bromo, um grupo acetila e um grupo funcional de éster metílico, que contribuem para sua reatividade e propriedades de solubilidade. Este composto geralmente aparece como um sólido branco a off-white e é solúvel em solventes orgânicos polares. A presença do átomo de bromo torna-o um potencial eletrófilo, que pode participar de várias reações químicas, incluindo substituições nucleofílicas. Os grupos acetila e éster metílico aumentam sua estabilidade e influenciam sua atividade biológica, tornando-o de interesse na pesquisa bioquímica e na química orgânica sintética. Além disso, sua estrutura permite que interaja com macromoléculas biológicas, o que pode ter implicações no desenvolvimento de medicamentos e aplicações terapêuticas. Assim como muitas substâncias químicas, o manuseio deve ser feito com cuidado, seguindo os protocolos de segurança apropriados devido aos perigos potenciais associados a compostos bromados.

Fórmula: C₁₃H₁₇BrO₉

InChI: InChI=1S/C13H17BrO9/c1-5(15)20-8-9(21-6(2)16)11(13(18)19-4)23-12(14)10(8)22-7(3)17/h8-12H,1-4H3/t8-,9-,10+,11-,12-/m0/s1

Chave InChI: InChIKey=GWTNLHGTLIBHHZ-SVNGYHJRSA-N

SMILES: O(C(C)=O)[C@H]1[C@H](OC(C)=O)[C@@H](C(OC)=O)O[C@H](Br)[C@@H]1OC(C)=O

Sinónimos:

• (2S,3S,4S,5R,6R)-methyl 3,4,5-triacetoxy-6-bromo-tetrahydro-2H-pyran-2-carboxylate
• Acetobromo-alpha-D-glucuronic acid methyl ester
• Acetobromo-α-<span class="text-smallcaps">D</span>-glucuronic acid methyl ester
• Glucopyranuronic acid, 1-bromo-1-deoxy-, methyl ester, triacetate, α-<span class="text-smallcaps">D</span>-
• Glucuronic acid, 1-bromo-1-deoxy-, methyl ester, 2,3,4-triacetate
• Methyl (2,3,4-tri-O-acetyl-α-<span class="text-smallcaps">D</span>-glucopyranosyl bromide)uronate
• Methyl (tri-O-acetyl-α-<span class="text-smallcaps">D</span>-glucopyranosyl bromide)uronate
• Methyl 1-bromo-1-deoxy-2,3,4-tri-O-acetyl-α-<span class="text-smallcaps">D</span>-glucopyranuronate
• Methyl 2,3,4-tri-O-acetyl-1-bromo-1-deoxy-α-<span class="text-smallcaps">D</span>-glucopyranosyluronate
• Methyl 2,3,4-tri-O-acetyl-1-bromo-1-deoxy-α-<span class="text-smallcaps">D</span>-glucopyranuranate
• Methyl 2,3,4-tri-O-acetyl-1-bromo-α-<span class="text-smallcaps">D</span>-glucopyranuronate
• Methyl 2,3,4-tri-O-acetyl-α-bromoglucuronate
• Methyl acetobromoglucuronate
• Methyl tri-O-acetyl-1-bromo-1-deoxy-alpha-D-glucopyranuronate
• Methyl α-acetobromglucuronate
• Methyl α-acetobromoglucuronate
• alpha-D-Glucopyranuronic acid, 1-bromo-1-deoxy-, methyl ester, triacetate
• methyl 2,3,4-tri-O-acetyl-alpha-D-glucopyranosyluronate bromide
• methyl 2,3,4-tri-O-acetylhexopyranosyluronate bromide
• α-<span class="text-smallcaps">D</span>-Glucopyranuronic acid, 1-bromo-1-deoxy-, methyl ester, 2,3,4-triacetate
• α-<span class="text-smallcaps">D</span>-Glucopyranuronic acid, 1-bromo-1-deoxy-, methyl ester, triacetate
• α-D-Glucopyranuronic acid, 1-bromo-1-deoxy-, methyl ester, 2,3,4-triacetate
• α-D-Glucopyranuronic acid, 1-bromo-1-deoxy-, methyl ester, triacetate

Acetobromo-α-D-glucuronic Acid Methyl Ester

CAS: 21085-72-3

Fórmula: C₁₃H₁₇BrO₉

Pureza: >95.0%(GC)

Cor e Forma: White to Light gray to Light yellow powder to crystal

Peso molecular: 397.17

Ref: 3B-A3379

Methyl acetobromo-α-D-glucuronate

CAS: 21085-72-3

Fórmula: C₁₃H₁₇BrO₉

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 397.1727

Ref: IN-DA00385Z

Acetobromo-α-D-glucuronic acid, methyl ester

CAS: 21085-72-3

Acetobromo-α-D-glucuronic acid, methyl ester

Fórmula: C₁₃H₁₇BrO₉

Pureza: 98%

Cor e Forma: white crystalline solid

Peso molecular: 397.17267g/mol

Ref: 54-BIA6200

Acetobromo-α-D-glucuronic acid, methyl ester

CAS: 21085-72-3

Acetobromo-α-D-glucuronic acid, methyl ester

Fórmula: C₁₃H₁₇BrO₉

Pureza: 95%

Cor e Forma: white crystalline solid

Peso molecular: 397.17g/mol

Ref: 54-OR6200T

Acetobromo-a-D-glucuronic acid methyl ester

CAS: 21085-72-3

Fórmula: C₁₃H₁₇BrO₉

Pureza: ≥ 95.0% (anhydrous basis, exc. stabiliser)

Cor e Forma: White to off-white powder

Peso molecular: 397.17

Ref: 7W-GC3316

Acetobromo-α-D-glucuronic Acid Methyl Ester (contains 2% CaCO3)

CAS: 21085-72-3

Stability Moisture Sensitive, Temperature Sensitive
Applications Acetobromo-α-D-glucuronic Acid Methyl Ester (cas# 21085-72-3) is a useful compound for preparing a fluorogenic probe for human heparanase.
References Honda, T., et al.: J. Med. Chem., 31, 1295 (1988), Liu, J., et al.: Chem. Sci., (2020)

Fórmula: C₁₃H₁₇BrO₉

Cor e Forma: White To Beige

Peso molecular: 397.17

Ref: TR-A162000

1-Bromo-2,3,4-tri-O-acetyl-a-D-glucuronide methyl ester - 1% CaCO3

CAS: 21085-72-3

1-Bromo-2,3,4-tri-O-acetyl-a-D-glucuronide methyl ester is a protected D-glucoronic acid with an alpha bromide at the anomeric position ready to undergo glycosylation reactions with suitable glycoside acceptors. Pharmaceutically active compounds have been used as acceptors to form β-linked D-glucuronide prodrugs which can be used to modify pharmacokinetics, improve solubility and lower the toxicity of the drug.

Fórmula: C₁₃H₁₇BrO₉

Pureza: Min. 98 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 397.17 g/mol

Ref: 3D-MB04460

1-Bromo-2,3,4-tri-O-acetyl-a-D-glucuronide methyl ester

CAS: 21085-72-3

1-Bromo-2,3,4-tri-O-acetyl-a-D-glucuronide methyl ester is a protected D-glucoronic acid with an alpha bromide at the anomeric position ready to undergo glycosylation reactions with suitable glycoside acceptors. Pharmaceutically active compounds have been used as acceptors to form β-linked D-glucuronide prodrugs which can be used to modify pharmacokinetics, improve solubility and lower the toxicity of the drug.

Fórmula: C₁₃H₁₇BrO₉

Pureza: Min. 80%

Peso molecular: 397.17 g/mol

Ref: 3D-MB31644

Acetobromo-a-D-glucuronic acid methyl ester

CAS: 21085-72-3

Fórmula: C₁₃H₁₇BrO₉

Pureza: 95%

Cor e Forma: Solid, Crystalline Powder or Powder

Peso molecular: 397.174

Ref: 10-F050538

Acetobromo-α-D-glucuronic Acid-13C6 Methyl Ester

Produto Controlado

CAS: 21085-72-3

Fórmula: C₆C₇H₁₇BrO₉

Cor e Forma: Neat

Peso molecular: 403.129

Ref: TR-A162002