CAS 2188-18-3

N2-[(1,1-Dimetiletoxicarbonil)]-N5-[imino(nitroamino)metil]-L-ornitina

Descrição:

N2-[(1,1-Dimetiletoxicarbonil)]-N5-[imino(nitroamino)metil]-L-ornitina, com o número CAS 2188-18-3, é um composto sintético que pertence à classe de aminoácidos e derivados. Esta substância apresenta uma estrutura complexa caracterizada pela presença de uma espinha dorsal de ornitina, que é um aminoácido importante envolvido no ciclo da ureia. A molécula é modificada com um grupo dimetiletoxicabonoil, melhorando sua estabilidade e solubilidade. Além disso, a presença de um grupo imino e funcionalidade nitroamino sugere reatividade potencial e atividade biológica, possivelmente influenciando seu papel em vias bioquímicas. O composto pode exibir propriedades como ser um intermediário potencial na síntese de produtos farmacêuticos ou agroquímicos. Sua estrutura única também pode conferir interações específicas com alvos biológicos, tornando-o de interesse na química medicinal. No entanto, estudos detalhados sobre sua atividade biológica, toxicidade e impacto ambiental seriam necessários para entender completamente suas características e aplicações.

Fórmula: C₁₁H₂₁N₅O₆

InChI: InChI=1S/C11H21N5O6/c1-11(2,3)22-10(19)14-7(8(17)18)5-4-6-13-9(12)15-16(20)21/h7H,4-6H2,1-3H3,(H,14,19)(H,17,18)(H3,12,13,15)/t7-/m0/s1

Chave InChI: InChIKey=OZSSOVRIEPAIMP-ZETCQYMHSA-N

SMILES: [C@H](NC(OC(C)(C)C)=O)(CCCNC(NN(=O)=O)=N)C(O)=O

Sinónimos:

• (2S)-2-(tert-Butoxycarbonylamino)-5-[(N-nitrocarbamimidoyl)amino]pentanoic acid
• (2S)-2-[[(tert-Butoxy)carbonyl]amino]-5-(N′-nitrocarbamimidamido)pentanoic acid
• (2S)-5-[Amino(nitramido)methylidene]azaniumyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate
• <span class="text-smallcaps">L</span>-Ornithine, N²-[(1,1-dimethylethoxy)carbonyl]-N⁵-[imino(nitroamino)methyl]-
• Boc-Arg(NO2)-OH
• Boc-Arg(No2)
• Boc-L-nitroarginine
• N-Boc-N'-nitro-L-arginine
• N²-[(1,1-Dimethylethoxy)carbonyl]-N⁵-[imino(nitroamino)methyl]-<span class="text-smallcaps">L</span>-ornithine
• N²-tert-Butoxycarbonyl-N^G-nitroarginine
• N²-tert-Butyloxycarbonyl-N^ω-nitro-<span class="text-smallcaps">L</span>-arginine
• N^α-tert-Butoxycarbonyl-N^G-nitro-<span class="text-smallcaps">L</span>-arginine
• N^α-tert-Butoxycarbonyl-N^G-nitroarginine
• Ornithine, N²-carboxy-N⁵-(nitroamidino)-, N-tert-butyl ester
• Ornithine, N²-carboxy-N⁵-(nitroamidino)-, N²-tert-butyl ester, <span class="text-smallcaps">L</span>-
• Nα-tert-Butoxycarbonyl-NG-nitro-L-arginine
• Ornithine, N2-carboxy-N5-(nitroamidino)-, N-tert-butyl ester
• N2-[(1,1-Dimethylethoxy)carbonyl]-N5-[imino(nitroamino)methyl]-L-ornithine
• L-Ornithine, N2-[(1,1-dimethylethoxy)carbonyl]-N5-[imino(nitroamino)methyl]-

Nα-Boc-N^w-nitro-L-arginine, 98%

CAS: 2188-18-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₁H₂₁N₅O₆

Pureza: 98%

Peso molecular: 319.32

Ref: 02-H62339

Boc-Arg(NO₂)-OH

CAS: 2188-18-3

The nitro group of the guanidyl residue can be removed by treating the blocked peptide with HF at 0 °C for 40 min.

Fórmula: C₁₁H₂₁N₅O₆

Pureza: > 99%

Cor e Forma: White Powder

Peso molecular: 319.32

Ref: 01-4001219

N-Boc-N'-Nitro-L-arginine

CAS: 2188-18-3

Fórmula: C₁₁H₂₁N₅O₆

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 319.3143

Ref: IN-DA0038VM

N-α-BOC-N-ω-Nitro-L-arginine

CAS: 2188-18-3

N-α-BOC-N-ω-Nitro-L-arginine

Fórmula: C₁₁H₂₁N₅O₆

Pureza: 98%

Cor e Forma: off-white solid

Peso molecular: 319.31g/mol

Ref: 54-OR0122

Boc-Arg(NO2)-OH

CAS: 2188-18-3

Peso molecular: 319.31

Ref: 7W-GM5650

Boc-Arg(NO2)-OH

CAS: 2188-18-3

Fórmula: C₁₁H₂₁N₅O₆

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 319.32

Ref: 3B-B4496

Boc-L-Arg(NO2)-OH

CAS: 2188-18-3

Fórmula: C₁₁H₂₁N₅O₆

Peso molecular: 319.32

Ref: 4Z-A-9232

Boc-L-Nitroarginine

Produto Controlado

CAS: 2188-18-3

Applications Boc-L-Nitroarginine, can be used in peptide chemistry. It has been also shown to act as NO synthase inhibitor, and thus used in the study of The effects of methylene blue (MB) for treatment of sepsis induced by bowel perforation.
References Galili, Y. Euro. surg. Rese. vol. 29, P:390-395 (19997);

Fórmula: C₁₁H₂₁N₅O₆

Cor e Forma: Neat

Peso molecular: 319.31

Ref: TR-B391615

Boc-Arg(NO2)-OH

CAS: 2188-18-3

Boc-Arg(NO2)-OH is an activated molecule that is used as an anticoagulant. It inhibits the serine protease, which has an inhibitory effect on heparin-induced thrombocytopenia, and also inhibits platelet aggregation. Boc-Arg(NO2)-OH has been shown to have a potent inhibition of the enzyme that converts prothrombin into thrombin. This effect can be reversed by adding protamine sulfate. The clinical data suggest that this drug may be beneficial for patients with severe or life-threatening conditions who are taking heparin therapy or undergoing surgery and need anticoagulation. The prognosis of this drug is unclear, but it appears to be safe when administered in conjunction with other medications such as aspirin and warfarin.

Fórmula: C₁₀H₁₉NO₄

Pureza: Min. 95%

Peso molecular: 319.32 g/mol

Ref: 3D-BLR-2058

BOC-Nitro-L-Arginine extrapure, 99%

CAS: 2188-18-3

Fórmula: C₁₁H₂₁N₅O₆

Pureza: min. 99%

Cor e Forma: White, Powder

Peso molecular: 319.31

Ref: SR-53717

Boc-Arg(NO2)-OH

CAS: 2188-18-3

M03259 - Boc-Arg(NO2)-OH

Fórmula: C₁₁H₂₁N₅O₆

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 319.318

Ref: 10-M03259

Boc-L-Nitroarginine

CAS: 2188-18-3

Fórmula: C₁₁H₂₁N₅O₆

Peso molecular: 319.32

Ref: ST-EA-CP-A123015

Boc-L-Nitroarginine

CAS: 2188-18-3

Boc-L-Nitroarginine is a nitric oxide synthase inhibitor that belongs to the class of drugs called nitric oxide inhibitors. It is a potent inhibitor of nitric oxide synthase, preventing the production of nitric oxide from arginine. The drug has been shown to have therapeutic effects in the treatment of cancer, diabetes mellitus, and other diseases. Boc-L-Nitroarginine inhibits tumor angiogenesis by blocking endothelial cell proliferation and migration. It also inhibits insulin secretion, leading to an improved glycemic control in diabetic patients. Boc-L-Nitroarginine can be used as a hydrogenation reducing agent for the synthesis of imatinib and palladium catalysts for hydrogenation reactions.

Fórmula: C₁₁H₂₁N₅O₆

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 319.31 g/mol

Ref: 3D-FB39246