CAS 219821-37-1

Aprepitant Impurity 9

CAS: 1803189-49-2, 219821-37-1

Fórmula: C₂₄H₂₅F₇N₄O₄

Cor e Forma: Pale Yellow Solid

Peso molecular: 566.48

Ref: 4Z-A-3228

2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenyl-4-[(2-N-methoxycarbonyl)acetamidrazono]morpholine-13C2,d2

Produto Controlado

CAS: 219821-37-1

Applications Labelled Aprepitant derivative.
References Ballard, T., et al.: Eur. J. Pharmacol., 412, 255 (2001), Campos, D., et al.: J. Clin. Oncol., 19, 1759 (2001), Severini, C., et al.: Pharmacol. Rev., 54, 285 (2002)

Fórmula: C₂₂C₂H₂₃D₂F₇N₄O₄

Cor e Forma: Neat

Peso molecular: 570.47

Ref: TR-B657147

N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant

Produto Controlado

CAS: 219821-37-1

Fórmula: C₂₄H₂₅F₇N₄O₄

Cor e Forma: Neat

Peso molecular: 566.468

Ref: TR-D297840

N-(Destriazolonomethyl) N-(methylcarboxyacetamidohydrazono) aprepitant

CAS: 219821-37-1

Aprepitant is a peptide that is an inhibitor of the neurokinin 1 (NK1) receptor. It has been shown to bind to both the free and bound forms of this receptor, inhibiting its activity. Aprepitant is a potent activator of the NK2 receptor, which may be why it also produces strong antiemetic effects. The compound has high purity, with no detectable impurities or aggregates. Aprepitant is used as a research tool in cell biology and pharmacology studies, as well as for the treatment of nausea and vomiting caused by cancer chemotherapy. It binds to the NK1 receptor in the central nervous system, blocking substance P from binding to its receptors on neurons. This prevents substance P from stimulating nerve cells and producing nausea and vomiting.

Fórmula: C₂₄H₂₅F₇N₄O₄

Pureza: Min. 95%

Peso molecular: 566.50 g/mol

Ref: 3D-UIA82137

Fosaprepitant Dimeglumine Impurity B

CAS: 219821-37-1

Fórmula: C₂₄H₂₅F₇N₄O₄

Peso molecular: 566.48

Ref: ST-EA-CP-F36002