CAS 2204442-52-2

Sorafenib Impurity 6

CAS: 2204442-52-2

Fórmula: C₂₇H₂₃N₅O₆

Cor e Forma: Off-White Solid

Peso molecular: 513.51

Ref: 4Z-S-2716

Methyl 4-(4-(3-(4-((2-(Methylcarbamoyl)pyridin-4-yl)oxy)phenyl)ureido)phenoxy)picolinate

Produto Controlado

CAS: 2204442-52-2

Applications Des-(4-chloro-3-trifluoromethyl)-4-(methyl-4-hydroxypicolinate) Sorafenib is an impurity of Sorafenib (S676850), a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.
References Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003), Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004), Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004), Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006),

Fórmula: C₂₇H₂₃N₅O₆

Cor e Forma: Neat

Peso molecular: 513.501

Ref: TR-D297095

Sorafenib Impurity 1

CAS: 2204442-52-2

Fórmula: C₂₇H₂₃N₅O₆

Peso molecular: 513.51

Ref: ST-EA-CP-S16009