CAS 22252-43-3
:Ácido 7-aminodesacetoxicefalosporânico
Descrição:
Ácido 7-aminodesacetoxicefalosporânico (CAS 22252-43-3) é um intermediário crucial na síntese de antibióticos cefalosporínicos, que são amplamente utilizados para tratar infecções bacterianas. Este composto apresenta um anel beta-lactâmico, característico das cefalosporinas, que é essencial para sua atividade antibacteriana. Possui um grupo amino na posição 7, contribuindo para sua reatividade e capacidade de sofrer modificações químicas adicionais para produzir vários derivados de cefalosporinas. A estrutura também inclui um grupo deacetoxi, que o diferencia de outras cefalosporinas. Ácido 7-aminodesacetoxicefalosporânico é tipicamente um pó cristalino branco a off-white, solúvel em água e solventes orgânicos, tornando-o adequado para aplicações farmacêuticas. Sua estabilidade e reatividade são influenciadas pelo pH e temperatura, que são fatores críticos a serem considerados durante o armazenamento e manuseio. Este composto serve como um bloco de construção chave no desenvolvimento de antibióticos semissintéticos, destacando sua importância na química medicinal e na indústria farmacêutica.
Fórmula:C8H10N2O3S
InChI:InChI=1S/C8H10N2O3S/c1-3-2-14-7-4(9)6(11)10(7)5(3)8(12)13/h4,7H,2,9H2,1H3,(H,12,13)/t4-,7-/m1/s1
Chave InChI:InChIKey=NVIAYEIXYQCDAN-CLZZGJSISA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@H](N)C2=O)(SCC1C)[H]
Sinónimos:- (6R,7R)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- (6S,7S)-7-ammonio-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- 3-Methyl-7-amino-Δ<sup>3</sup>-cephem-4-carboxylic acid
- 3-Methyl-7-aminoceph-3-em-4-carboxylic acid
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-methyl-8-oxo-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-methyl-8-oxo-, (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-methyl-8-oxo-, (6R-trans)-
- 7-Adca
- 7-Amino-3-deacetoxycephalosporanic acid
- 7-Amino-3-desacetoxycephalosporanic acid
- 7-Amino-3-methyl-3-cephen-4-carboxylic acid
- 7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
- 7-Amino-3-methyl-Δ<sup>3</sup>-cephan-4-carboxylic acid
- 7-Amino-3-methyl-Δ<sup>3</sup>-cephem-4-carboxylic acid
- 7-Amino-3-methylcephalosporanic acid
- 7-Aminodeacetoxycephalexanic acid
- 7-Aminodeacetoxycephalosporanic acid
- 7-Aminodeacetoxycephalosporanic ccid
- 7-Aminodesacetoxycephalosporanic acid
- 7-β-Amino-3-methyl-3-cephem-4-carboxylic acid
- 7β-Amino-3-methylceph-3-em-4-carboxylic acid
- Deacetoxycephalosporanic acid
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16 produtos.
Cefadroxil Related Compound B ((6R,7R)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C8H10N2O3SCor e Forma:Off-White Crystalline PowderPeso molecular:214.041217-Aminodeacetoxycephalosporanic acid
CAS:7-Aminodeacetoxycephalosporanic acid (Cefalexine EP IMpurity B) is used as an antibiotic.Fórmula:C8H10N2O3SPureza:98.87% - 99.63%Cor e Forma:White Solid PowderPeso molecular:214.24(6R,7S)-7-AMINO-3-METHYL-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID
CAS:Fórmula:C8H10N2O3SPureza:97%Cor e Forma:SolidPeso molecular:214.2416Cefadroxil EP Impurity B (Cefadroxil USP Related Compound B, Cephalexin (Cephalexin) EP Impurity B, Cefradine EP Impurity A, 7-ADCA)
CAS:Fórmula:C8H10N2O3SCor e Forma:White To Off-White SolidPeso molecular:214.247-Aminodesacetoxycephalosporanic Acid
CAS:7-Aminodesacetoxycephalosporanic AcidPureza:98%Peso molecular:214.24g/mol7-Aminodeacetoxycephalosporanic acid
CAS:7-Aminodeacetoxycephalosporanic acidPureza:≥98%Peso molecular:214.24g/mol7-Aminodesacetoxycephalosporanic Acid
CAS:Produto ControladoFórmula:C8H10N2O3SCor e Forma:NeatPeso molecular:214.247-Aminodesacetoxycephalosporanic Acid
CAS:Fórmula:C8H10N2O3SPureza:>98.0%(HPLC)Cor e Forma:White to Orange to Green powder to crystallinePeso molecular:214.247-Aminodesacetoxycephalosporanic acid
CAS:Fórmula:C8H10N2O3SPureza:≥ 98.0%Cor e Forma:White to off-white or pale yellow powderPeso molecular:214.247-Aminodesacetoxycephalosporanic Acid
CAS:<p>Impurity Cefadroxil EP Impurity B<br>Applications 7-Aminodesacetoxycephalosporanic Acid (Cefadroxil EP Impurity B) is a metabolite of Cephalexin (C256800).<br>References Dantzig, A., et al.: Biochim. Biophys. Acta, 1027, 211 (1990), Shen, H., et al.: J. Biol. Chem., 278, 4786 (2003), Watanabe, C., et al.: Drug Metab. Pharmacokinet., 20, 443 (2005)<br></p>Fórmula:C8H10N2O3SCor e Forma:BeigePeso molecular:214.247-Aminodezacetoxycephalosporanic acid
CAS:Pureza:98.0%Cor e Forma:Solid, PowderPeso molecular:214.240005493164067-Aminodesacetoxycephalosporanic acid
CAS:7-Aminodesacetoxycephalosporanic acid is a chemical compound that is used for wastewater treatment as a biocatalyst. It has been shown to have group P2 activity and can be used in the treatment of corynebacterium glutamicum. 7-Adca has been found to bind to the magnesium salt, which leads to control analysis and kinetic studies. The reactions are initiated by the addition of an electron donor, such as penicillin, which results in a transfer reaction. The nitrogen atoms are substituted with hydrogen atoms, which produces a fatty acid intermediate. This intermediate reacts with nitrogen atoms from another molecule of 7-Adca or 7-adca to form an amide bond. The amide bond is then hydrolyzed in water to produce 7-aminodesacetoxycephalosporanic acid and ammonia.Fórmula:C8H10N2O3SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:214.24 g/mol
![(6R,7S)-7-AMINO-3-METHYL-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003NCS.jpg&w=3840&q=75)
