CAS 223673-61-8

Mirabegrona

Descrição:

Mirabegrona é um composto farmacêutico usado principalmente como medicamento para o tratamento da bexiga hiperativa. Funciona como um agonista seletivo dos receptores adrenérgicos beta-3, o que significa que estimula os receptores adrenérgicos beta-3 na bexiga, levando ao relaxamento do músculo detrusor e ao aumento da capacidade da bexiga. Esse mecanismo ajuda a aliviar sintomas como urgência e frequência urinária. Mirabegrona é caracterizado por sua lipofilicidade moderada, que influencia sua absorção e distribuição no corpo. O composto possui uma fórmula molecular que reflete sua estrutura complexa, incluindo vários grupos funcionais que contribuem para sua atividade farmacológica. É tipicamente administrado por via oral e tem uma meia-vida relativamente longa, permitindo a dosagem uma vez ao dia. Efeitos colaterais comuns podem incluir hipertensão, infecções do trato urinário e dor de cabeça. No geral, Mirabegrona representa um avanço significativo no manejo de condições urinárias, oferecendo uma alternativa aos medicamentos anticolinérgicos.

Fórmula: C₂₁H₂₄N₄O₂S

InChI: InChI=1/C21H24N4O2S/c22-21-25-18(14-28-21)12-20(27)24-17-8-6-15(7-9-17)10-11-23-13-19(26)16-4-2-1-3-5-16/h1-9,14,19,23,26H,10-13H2,(H2,22,25)(H,24,27)

Chave InChI: InChIKey=PBAPPPCECJKMCM-IBGZPJMESA-N

SMILES: N(C(CC1=CSC(N)=N1)=O)C2=CC=C(CCNC[C@H](O)C3=CC=CC=C3)C=C2

Sinónimos:

• (R)-Mirabegron
• 2-(2-Amino-1,3-thiazol-4-yl)-N-[4-[2-[((2R)-2-hydroxy-2-phenylethyl)amino]ethyl]phenyl]acetamide
• 2-(2-amino-1,3-thiazol-4-yl)-N-(4-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl}phenyl)acetamide
• 2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide
• 4-Thiazoleacetamide, 2-amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-
• Betanis
• Betmiga
• Mira veron
• Myrbetriq
• N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenyl)-2-(2-aminothiazol-4-yl)acetamide
• Ym 178
• Mirabegron
• Merariveron impurity B
• Mirabegron(YM 178)
• (R)-2-(2-aminothiazol-4-yl)-N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenyl)acetamide
• hot selling Mirabegron
• Mirabello
• Mirabegron USP/EP/BP
• Mirabegron Intermediates
• 2-(2-Amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy2-phenylethyl]amino}ethyl)phenyl]acetamide
• Mirabelon
• CS-732
• (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl}acetanilide
• MIRABEQRON
• (2R)-2-(2-AMinothiazol-4-yl)-4'-[2-[(2-hydroxy-2-phenylethyl)aMino]ethyl]acetic Acid Anilide
• Mirabegron, >=99%
• 2-AMino-N-[4-[2-[[(2R)-2-hydroxy-2-phenyl-ethyl]aMino]-ethyl]phenyl]-4-thiazoleacetaMide

Mirabegron

CAS: 223673-61-8

Mirabegron

Fórmula: C₂₁H₂₄N₄O₂S

Pureza: 99.9%

Cor e Forma: White

Peso molecular: 396.162

Ref: 47-1313

MIRABEGRON CRS

CAS: 223673-61-8

MIRABEGRON CRS

Ref: 41-Y0002371

Mirabegron

CAS: 223673-61-8

Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure

Fórmula: C₂₁H₂₄N₄O₂S

Cor e Forma: White Off-White Brownish Yellow Crystalline Powder

Peso molecular: 396.162

Ref: 45-1444106

Mirabegron

CAS: 223673-61-8

Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome.

Fórmula: C₂₁H₂₄N₄O₂S

Pureza: 99.64%

Cor e Forma: Light Yellow To Yellow Solid

Peso molecular: 396.51

Ref: TM-T1671

2-(2-amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)phenyl]acetamide

CAS: 223673-61-8

Fórmula: C₂₁H₂₄N₄O₂S

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 396.5059

Ref: IN-DA0037SU

Mirabegron

CAS: 223673-61-8

Mirabegron

Pureza: ≥98%

Peso molecular: 396.51g/mol

Ref: 54-BUP12771

Mirabegron

CAS: 223673-61-8

Mirabegron

Pureza: 98%

Peso molecular: 396.506g/mol

Ref: 54-OR1027819

Mirabegron

CAS: 223673-61-8

Fórmula: C₂₁H₂₄N₄O₂S

Cor e Forma: Pale Yellow Solid

Peso molecular: 396.51

Ref: 4Z-M-861

Mirabegron

CAS: 223673-61-8

Cor e Forma: Neat

Ref: 86-MM3776.00

Mirabegron

Produto Controlado

CAS: 223673-61-8

Fórmula: C₂₁H₂₄N₄O₂S

Cor e Forma: White

Peso molecular: 396.51

Ref: TR-M364900

Mirabegron

CAS: 223673-61-8

Mirabegron is a drug that is used for the treatment of urinary incontinence and overactive bladder. It is a selective beta 3 adrenergic receptor agonist that has been shown to increase detrusor muscle contractility, thereby improving the storage capacity of the bladder. Mirabegron also decreases post-voiding residual volume and increases total voided volume. Mirabegron acts by binding to its receptor in adipose tissue, which leads to increased lipolysis and reduced appetite. The effect on lipolysis may be due to mirabegron's ability to inhibit DPP-IV activity.

Fórmula: C₂₁H₂₄N₄O₂S

Pureza: Min. 95 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 396.51 g/mol

Ref: 3D-FM26011