CAS 2241300-50-3

AS2863619

CAS: 2241300-50-3

AS2863619 is a small-molecule drug that activates the phosphoinositide 3-kinase (PI3K) and mitogen activated protein kinase (MAPK) signaling pathways. It has been shown to have a functional effect on inflammatory cytokines, cell function, and hypomethylation of DNA. AS2863619 has also been shown to be able to activate the TGF-β pathway in vitro and in vivo. This compound is selective for certain regulatory kinases, such as PI3K and MAPK, but not others. AS2863619 is also an inhibitor of DNA methyltransferase 1 (DNMT1). As such, it is able to inhibit the expression of genes by preventing methylation of their promoter regions. The activation of these pathways leads to increased proliferation activity.

Fórmula: C₁₆H₁₂N₈O

Pureza: Min. 95%

Peso molecular: 332.32 g/mol

Ref: 3D-RPD30050

AS2863619 free base

CAS: 2241300-50-3

AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells.

Fórmula: C₁₆H₁₂N₈O

Cor e Forma: Solid

Peso molecular: 332.32

Ref: TM-T10382