CAS 224320-11-0

Pitavastatin 3-Ether Glucuronide

Produto Controlado

CAS: 224320-11-0

Applications Pitavastatin 3-Ether Glucuronide is an metabolite of Pitavastatin, a competitive inhibitor of HMG-CoA reductase and is a known antilipemic agent.
References Yamada, I., et al.: Xenobiotica., 33, 789 (2003); Aoki, T., et al.: Arzneim.-Forsch., 47, 904 (1997); Yamada, I., et al.: Xenobiotica, 33, 789 (2003); Park, S., et al.: Clin. Ther., 27, 1074 (2005)

Fórmula: C₃₁H₃₂FNO₁₀

Cor e Forma: Neat

Peso molecular: 597.585

Ref: TR-P531030

Pitavastatin 3-O-glucuronide

CAS: 224320-11-0

Pitavastatin 3-O-glucuronide is a synthetic, water soluble glycosylate prodrug of pitavastatin, a third generation HMG-CoA reductase inhibitor. Pitavastatin 3-O-glucuronide has been shown to be effective in lowering serum cholesterol and triglycerides in humans. This drug is metabolized by hydrolysis of the glucuronide moiety and cleavage of the sugar moiety to form active pitavastatin. Pitavastatin 3-O-glucuronide also has an increased stability against oxidation compared to pitavastatin.

Fórmula: C₃₁H₃₁FNO₁₀

Pureza: Min. 95%

Peso molecular: 596.58 g/mol

Ref: 3D-MP35494