CAS 22465-48-1

Acetato de cobalamina

Descrição:

Acetato de cobalamina, também conhecido como acetato de vitamina B12, é um derivado da cobalamina, que é essencial para várias funções biológicas no corpo humano. É caracterizado por sua estrutura de anel corrin contendo cobalto, que é central para sua atividade como cofator em reações enzimáticas, particularmente na síntese de DNA e na formação de glóbulos vermelhos. Acetato de cobalamina é tipicamente um pó cristalino vermelho, refletindo a cor característica dos compostos de vitamina B12. É solúvel em água e exibe estabilidade em condições normais, embora possa ser sensível à luz e ao calor. Este composto desempenha um papel crucial no metabolismo de ácidos graxos e aminoácidos, e sua deficiência pode levar a sérios problemas de saúde, incluindo anemia e distúrbios neurológicos. Acetato de cobalamina é frequentemente usado em suplementos dietéticos e alimentos fortificados para prevenir ou tratar a deficiência de vitamina B12. Sua biodisponibilidade e eficácia no corpo fazem dele um composto importante na ciência nutricional e na medicina.

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

InChI: InChI=1S/C62H90N13O14P.C2H4O2.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2(3)4;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3,(H,3,4);/q;;+3/p-3

Chave InChI: InChIKey=KPFAAKYTRSSOQN-UHFFFAOYSA-K

SMILES: [O-](C(C)=O)[Co+3]1234[N]=5C6(C)C7[N-]1C(C(C)(C7CC(N)=O)CCC(=O)NCC(C)OP(=O)([O-])OC8C(O)C(N9C=[N]2C=%10C9=CC(C)=C(C)C%10)OC8CO)=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5C(CCC(N)=O)C6(CC(N)=O)C)C(CC(N)=O)(C)C%12CCC(N)=O)C(C)(C)C%11CCC(N)=O

Sinónimos:

• Acetatocobalamin
• Co(Acetato-kappaO)cobinamide dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
• Cobalamin, acetato-
• Cobalamin, acetato- (6CI)
• Cobinamide, Co(acetato-kappaO)-, dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
• Cobinamide, Co-(acetato-κO)-, dihydrogen phosphate (ester), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³)
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
• Cobinamide, acetate phosphate, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole, inner salt
• Depo-gamma
• Fresmin S
• Hydroxocobalamine acetate
• Hydroxycobalamine acetate
• Novidroxin
• Twelvmin
• Unii-S535M27N3Q
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole
• Cobinamide, acetate phosphate, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole, inner salt

Hydroxocobalamin Acetate

CAS: 22465-48-1

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Pureza: >90.0%(HPLC)

Cor e Forma: Orange to Brown to Dark red powder to crystal

Peso molecular: 1,388.41

Ref: 3B-H1542

Hydroxocobalamin Acetate

CAS: 22465-48-1

Vitamin b12 (cyanocobalamin and related compounds with vitamin b12 activity) and its derivatives

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Cor e Forma: Dark Red Powder

Peso molecular: 1387.57763

Ref: 45-1324308

Hydroxocobalamin acetate

CAS: 22465-48-1

Hydroxocobalamin acetate treats B12 deficiency and cyanide poisoning; FDA-approved with few side effects.

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Pureza: 96.73%

Cor e Forma: Solid

Peso molecular: 1388.39

Ref: TM-T13730

Hydroxocobalamin acetate

CAS: 22465-48-1

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Pureza: 96.0 - 102.0 %

Cor e Forma: Dark red crystalline powder or crystals

Peso molecular: 1388.39

Ref: 7W-GE5819

Hydroxycobalamine Acetate

CAS: 22465-48-1

Hydroxycobalamine Acetate

Pureza: 98%

Peso molecular: 1,388.39g/mol

Ref: 54-OR1013546

Hydroxocobalamin Acetate (Vitamin B12 Analog)

CAS: 22465-48-1

Fórmula: C₆₄H₉₂CoN₁₃O₁₆P

Cor e Forma: Dark Red Solid

Peso molecular: 1389.42

Ref: 4Z-V-035001

Hydroxocobalamin acetate

CAS: 22465-48-1

Hydroxocobalamin acetate

Pureza: ≥95%

Peso molecular: 1388.39g/mol

Ref: 54-BUP14167

Hydroxocobalamin Acetate

CAS: 22465-48-1

Fórmula: C₆₂H₈₉CoN₁₃O₁₅PC₂H₄O₂

Peso molecular: 1346.38 : 60.05

Ref: ST-EA-CP-H13001

Hydroxocobalamin Acetate

Produto Controlado

CAS: 22465-48-1

Applications Physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic). References Kaczka, E.A., et al.: Science, 112, 354 (1950), Friedrich, W., et al.: Vitamins, 837 (1988), Forsyth, J.C., et al.: Clin. Toxicol., 31, 277 (1993),

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Cor e Forma: Dark Red

Peso molecular: 1388.39

Ref: TR-H826800

Hydroxocobalamin acetate

CAS: 22465-48-1

Hydroxocobalamin acetate is a water-soluble form of hydroxocobalamin, a vitamin B12 prodrug. It is an insoluble polymer that dissolves slowly in an acidic environment. Hydroxocobalamin acetate has been shown to inhibit the growth of human carcinoma cells in culture and can be used as a test compound for anticancer drugs. Hydroxocobalamin acetate is also used as a mouth rinse agent to prevent or treat dental cavities. In addition, it can be used to relieve the symptoms of gastroesophageal reflux disease (GERD) by reducing the acidity of gastric contents. This drug has been shown to stimulate vasoactive intestinal polypeptide release from enterochromaffin cells and can be used for the treatment of irritable bowel syndrome (IBS). Hydroxocobalamin acetate is poorly soluble in neutral pH environments and should not be given orally.

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Pureza: Min. 90 Area-%

Cor e Forma: Red Powder

Peso molecular: 1,388.39 g/mol

Ref: 3D-FH23894

Cobinamide, Co-(acetato-kO)-, dihydrogen phosphate (ester), innersalt, 3'-ester with(5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3)

CAS: 22465-48-1

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1388.3918

Ref: IN-DA00I4FP