CAS 2292-16-2

(-)-Neferina

Descrição:

(-)-Neferina é um alcaloide que ocorre naturalmente, extraído principalmente das sementes da planta de lótus, particularmente da espécie *Nelumbo nucifera*. É caracterizado por sua estrutura quiral, que contribui à sua atividade biológica. O composto exibe uma variedade de propriedades farmacológicas, incluindo efeitos anti-inflamatórios, antioxidantes e potencialmente neuroprotetores. (-)-Neferina despertou interesse na química medicinal devido à sua capacidade de modular várias vias biológicas, tornando-se um candidato para pesquisas adicionais em aplicações terapêuticas. A substância é tipicamente estudada no contexto da medicina tradicional e da farmacologia moderna, com investigações em andamento sobre seus mecanismos de ação e eficácia. Sua solubilidade e estabilidade podem variar dependendo do solvente e das condições, o que é crucial para sua aplicação em estudos biológicos. No geral, (-)-Neferina representa um composto significativo no campo dos produtos naturais e da farmacognosia, destacando a importância das substâncias derivadas de plantas na descoberta de medicamentos.

Fórmula: C₃₈H₄₄N₂O₆

InChI: InChI=1/C38H44N2O6/c1-39-15-14-27-21-36(44-5)38(23-30(27)31(39)17-24-7-10-28(42-3)11-8-24)46-34-19-25(9-12-33(34)41)18-32-29-22-37(45-6)35(43-4)20-26(29)13-16-40(32)2/h7-12,19-23,31-32,41H,13-18H2,1-6H3/t31-,32-/m1/s1

Chave InChI: InChIKey=MIBATSHDJRIUJK-ZWXJPIIXSA-N

SMILES: C([C@@H]1C=2C(=CC(OC)=C(OC3=CC(C[C@H]4C=5C(=CC(OC)=C(OC)C5)CCN4C)=CC=C3O)C2)CCN1C)C6=CC=C(OC)C=C6

Sinónimos:

• 4-[[(1R)-6,7-Dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol
• 4-[[(1S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]phenol
• 4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-2-{[(1R)-6-methoxy-1-(4-methoxybenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}phenol
• 4′′-O-Methylliensinine
• Methylliensinine
• Neferin
• Phenol, 4-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]-
• Neferine
• 4-[[(1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-6-methoxy-1-(4-methoxybenzyl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol
• Neferine USP/EP/BP
• 4-[(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)methyl]-2-[[1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methylisoquinolin-7-yl]oxy]phenol

Phenol, 4-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]-

CAS: 2292-16-2

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 624.7658

Ref: IN-DA002LIY

Neferine

CAS: 2292-16-2

Fórmula: C₃₈H₄₄N₂O₆

Peso molecular: 624.78

Ref: 7W-GY2445

Neferine

CAS: 2292-16-2

Neferine

Pureza: ≥98%

Peso molecular: 624.77g/mol

Ref: 54-BUP06165

4-(((S)-6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl)-2-(((R)-6-Methoxy-1-(4-Methoxybenzyl)-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-7-Yl)Oxy)Phenol

CAS: 2292-16-2

4-(((S)-6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl)-2-(((R)-6-Methoxy-1-(4-Methoxybenzyl)-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-7-Yl)Oxy)Phenol

Pureza: 98%

Peso molecular: 624.77g/mol

Ref: 54-OR1023075

Neferine

CAS: 2292-16-2

Neferine

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 95%~99%

Peso molecular: 624.778

Ref: BP-BP0987

Neferine

CAS: 2292-16-2

Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 98.81% - 99.65%

Cor e Forma: Solid

Peso molecular: 624.77

Ref: TM-T5S1097

Neferine

CAS: 2292-16-2

Fórmula: C₃₈H₄₄N₂O₆

Peso molecular: 624.78

Ref: 4Z-N-107001

Neferine

CAS: 2292-16-2

Neferine is an alkaloid, which is derived from the seeds of Nelumbo nucifera, commonly known as the lotus plant. This compound acts as a bioactive molecule with diverse pharmacological properties, primarily through its antioxidant and neuroprotective modes of action. Neferine functions by scavenging reactive oxygen species and inhibiting oxidative stress pathways, making it significant in cellular protection. Furthermore, it modulates various signaling pathways that are crucial for maintaining cellular homeostasis and survival.

Fórmula: C₃₈H₄₄N₂O₆

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 624.77 g/mol

Ref: 3D-FN65588