CAS 2321332-57-2

CPTH6 hydrobromide

CAS: 2321332-57-2

CPTH6, a thiazole derivative, selectively inhibits the lysine acetyltransferase activity of Gcn5 and pCAF without affecting p300 or CBP. It effectively blocks the acetylation of H3/H4 histones and α-tubulin in various leukemia cell lines, leading to reduced cell viability by arresting the cell cycle in the G0/G1 phase and inducing apoptosis. Additionally, CPTH6 disrupts autophagy across several tumor cell lines, primarily by interfering with ATG7-mediated autophagosomal membrane elongation.

Fórmula: C₁₅H₁₆ClN₃SHBr

Cor e Forma: Solid

Peso molecular: 386.7

Ref: TM-T84391

Cpth6 (hydrobromide)

CAS: 2321332-57-2

Cpth6 is a peptide that is used as a research tool for the study of ion channels and protein interactions. Cpth6 has been shown to inhibit the activity of a wide range of ion channels, including potassium, sodium and calcium channels. It also inhibits the binding of ligands to their receptors and has been used in pharmacological studies on drugs with analgesic or sedative effects. Cpth6 is an inhibitor that binds to ATP-binding proteins in the plasma membrane, preventing ATP from being hydrolyzed and released into solution. This inhibition leads to cell death by preventing cellular processes such as DNA replication, protein synthesis, and cell division.

Fórmula: C₁₅H₁₇BrClN₃S

Pureza: Min. 95%

Peso molecular: 386.70 g/mol

Ref: 3D-WSD33257