CAS 23642-66-2

Hidrocloreto de benfluorex

Descrição:

Hidrocloreto de benfluorex é um composto sintético usado principalmente como medicamento antiobesidade e tem sido associado ao tratamento de distúrbios metabólicos. É um derivado da fenfluramina e atua como um agonista do receptor de serotonina, influenciando a regulação do apetite e o gasto energético. A substância é tipicamente apresentada como um pó cristalino branco a off-white, que é solúvel em água e exibe um perfil de estabilidade moderado em condições padrão. Sua estrutura química inclui um anel fenílico fluorurado, contribuindo para suas propriedades farmacológicas. Hidrocloreto de benfluorex tem sido notado por seus potenciais efeitos colaterais, incluindo problemas cardiovasculares, o que levou à sua retirada de vários mercados. Assim como muitos fármacos, seu uso requer consideração cuidadosa da dosagem e do estado de saúde do paciente, e está sujeito a escrutínio regulatório. No geral, embora tenha aplicações terapêuticas, o perfil de segurança e o status regulatório de Hidrocloreto de benfluorex exigem uso cauteloso e avaliação contínua em ambientes clínicos.

Fórmula: C₁₉H₂₀F₃NO₂·ClH

InChI: InChI=1S/C19H20F3NO2.ClH/c1-14(12-15-6-5-9-17(13-15)19(20,21)22)23-10-11-25-18(24)16-7-3-2-4-8-16;/h2-9,13-14,23H,10-12H2,1H3;1H

Chave InChI: InChIKey=NLOALSPYZIIXEO-UHFFFAOYSA-N

SMILES: C(C(NCCOC(=O)C1=CC=CC=C1)C)C2=CC(C(F)(F)F)=CC=C2.Cl

Sinónimos:

• (±)-N-(2-Benzoyloxyethyl)norfenfluramine hydrochloride
• 2-((1-Methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)ethyl benzoate hydrochloride
• 2-((alpha-Methyl-m-(trifluoromethyl)phenethyl)amino)ethanol benzoate (ester)
• 2-(-Methyl-3-(trifluoromethyl)phenethylamino)ethyl benzoate hydrochloride
• 2-(alpha-Methyl-3-(trifluoromethyl)phenylethylamino)ethyl benzoat
• 2-({1-[3-(Trifluoromethyl)Phenyl]Propan-2-Yl}Amino)Ethyl Benzoate Hydrochloride (1:1)
• Balans
• Benfluorex HCl
• Ethanol, 2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)-, benzoate (ester), hydrochloride
• Ethanol, 2-((alpha-methyl-m-(trifluoromethyl)phenethyl)amino)-, benzoate (ester), HCl
• Ethanol, 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]-, 1-benzoate, hydrochloride (1:1)
• Ethanol, 2-[[α-methyl-m-(trifluoromethyl)phenethyl]amino]-, benzoate (ester), hydrochloride
• Jp 992
• Lipophoral
• Mediator
• Mediaxal
• S 992
• Unii-X7O165Xz00
• Benfluorex hydrochloride

2-((1-(3-(Trifluoromethyl)phenyl)propan-2-yl)amino)ethyl benzoate hydrochloride

CAS: 23642-66-2

Fórmula: C₁₉H₂₁ClF₃NO₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 387.8237

Ref: IN-DA002O0S

2-({1-[3-(Trifluoromethyl)phenyl]prop-2-yl}amino)ethyl benzoate hydrochloride

CAS: 23642-66-2

2-({1-[3-(Trifluoromethyl)phenyl]prop-2-yl}amino)ethyl benzoate hydrochloride

Pureza: ≥95%

Peso molecular: 387.82g/mol

Ref: 54-PC8120

Benfluorex hydrochloride

Produto Controlado

CAS: 23642-66-2

Fórmula: C₁₉H₂₁ClF₃NO₂

Cor e Forma: Neat

Peso molecular: 387.82

Ref: 04-C10469000

Benfluorex Hydrochloride

Produto Controlado

CAS: 23642-66-2

Applications Used as an antihyperlipoproteinemic therapeutic.
References Beckett, A.H., et al.: J. Pharm. Pharmacol., 23, 950 (1971), Brindley, D.N., et al.: J. Pharm. Pharmacol., 28, 670 (1976)

Fórmula: C₁₉H₂₁ClF₃NO₂

Cor e Forma: White Solid

Peso molecular: 387.82

Ref: TR-B135000

Benfluorex hydrochloride

Produto Controlado

CAS: 23642-66-2

Benfluorex hydrochloride is a fluorinated derivative of benfluorex, which is an experimental drug for the treatment of bone cancer. It was shown to be effective in treating bowel disease, primary pulmonary hypertension and carcinoid syndrome in animal models. Benfluorex hydrochloride inhibits the activity of enzymes that are involved in the metabolism of carbohydrates and lipids. It has been shown to increase uric acid levels and inhibit the activity of enzymes that are involved in the synthesis of amino acids. This leads to cell lysis and an increased production of glucose-6-phosphate. The use of benfluorex hydrochloride as a diagnostic tool has been studied extensively, with its most notable application being its use as a marker for group P2 enzyme activities.

Fórmula: C₁₉H₂₀F₃NO₂•HCl

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 387.82 g/mol

Ref: 3D-FB103383