CAS 23736-58-5

Cloxacilina benzatina

Descrição:

Cloxacilina benzatina é um antibiótico semissintético pertencente à classe das penicilinas, projetado especificamente para combater infecções bacterianas. É uma combinação de cloxacilina, que é eficaz contra estafilococos produtores de penicilinase, e benzatina, que serve como um veículo de ação prolongada para o medicamento. Esta formulação permite efeitos terapêuticos prolongados, tornando-o adequado para tratar infecções que requerem níveis sustentados de antibióticos na corrente sanguínea. Cloxacilina benzatina é tipicamente administrado por injeção intramuscular e é usado para tratar várias infecções, incluindo infecções de pele e tecidos moles, infecções do trato respiratório e certos tipos de endocardite. O composto exibe características típicas dos antibióticos beta-lactâmicos, incluindo a capacidade de inibir a síntese da parede celular bacteriana, levando à lise celular e morte. É importante notar que, assim como outras penicilinas, pode causar reações alérgicas em alguns indivíduos. Condições adequadas de armazenamento e adesão às diretrizes de dosagem são essenciais para garantir sua eficácia e segurança.

Fórmula: C₁₉H₁₈ClN₃O₅SC₁₆H₂₀N₂

InChI: InChI=1S/C19H18ClN3O5S.C16H20N2/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;1-3-7-15(8-4-1)13-17-11-12-18-14-16-9-5-2-6-10-16/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);1-10,17-18H,11-14H2/t13-,14+,17-;/m1./s1

Chave InChI: InChIKey=OUMOALQYXBRQFX-SLINCCQESA-N

SMILES: C(NCCNCC1=CC=CC=C1)C2=CC=CC=C2.N(C(=O)C=1C(=NOC1C)C2=C(Cl)C=CC=C2)[C@H]3[C@@]4(N([C@@H](C(O)=O)C(C)(C)S4)C3=O)[H]

Sinónimos:

• (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N'-dibenzylethane-1,2-diamine (2:1)
• 1,2-Ethanediamine, N,N′-bis(phenylmethyl)-, bis[(2S,5R,6R)-6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-1-carboxylate]
• 1,2-Ethanediamine, N,N′-bis(phenylmethyl)-, bis[[2S-(2α,5α,6β)]-6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-1-carboxylate]
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-, compd. with N,N′-dibenzylethylenediamine (2:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-, compd. with N,N′-bis(phenylmethyl)-1,2-ethanediamine (2:1)
• 6-({[3-(2-Chlorophenyl)-5-Methyl-1,2-Oxazol-4-Yl]Carbonyl}Amino)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid
• Benzathine cloxacillin
• Boviclox
• Cloxacillin benzathin
• Cloxacillin benzathine
• Dry-Clox
• Ethylenediamine, N,N′-dibenzyl-, bis[6-[3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-1-carboxylate]
• Ethylenediamine, N,N′-dibenzyl-, bis[6-[3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate]
• Noroclox DC
• Opticlox
• Orbenin Dry Cow
• Triclox

Cloxacillin benzathine

CAS: 23736-58-5

Cloxacillin benzathine

Fórmula: C₁₆H₂₀N₂(C₁₉H₁₈CIN₃O₅S)₂

Pureza: 95.5%

Cor e Forma: White

Peso molecular: 1318.16503

Ref: 47-88

Cloxacillin Benzathine

CAS: 23736-58-5

Penicillins and their derivatives with a penicillanic a

Fórmula: C₁₉H₁₈ClN₃O₅SC₁₆H₂₀N₂

Cor e Forma: White Powder

Peso molecular: 1112.11

Ref: 45-1141909

Cloxacillin Benzathine

CAS: 23736-58-5

Fórmula: C₁₉H₁₇ClN₃O₅S·Na·C₁₆H₂₀N₂

Peso molecular: 434.87 22.99 240.35

Ref: 4Z-C-191017

Cloxacillin Benzathine (2:1)

Produto Controlado

CAS: 23736-58-5

Applications Cloxacillin Benzathine is a salt of Cloxacillin is an antibiotic that belongs to the group of the isoxazolylpenicillins. Cloxacillin is used to treat infections caused by species of staphylococci that produce beta-lactamase due to its inhibitory effects on beta-lactamase binding.
References Gibbs, D.L. et al.: Curr. Microbiol., 2, 239 (1979); Dmitrova, D. et al.: Farmat., 48, 28 (2001); CRaven, N. et al.: Res. Vet. Sci., 29, 57 (1980);

Fórmula: C₁₉H₁₈ClN₃O₅S·C₁₆H₂₀N₂

Cor e Forma: Neat

Peso molecular: 1112.11

Ref: TR-C587465

Cloxacillin benzathine

CAS: 23736-58-5

Cloxacillin benzathine is a beta-lactam antibiotic, which is synthesized from Penicillium fungi-derived penicillins. It acts by inhibiting bacterial cell wall synthesis. The mechanism involves the irreversible inhibition of penicillin-binding proteins (PBPs). This disruption in the bacterial cell wall structure ultimately leads to cell lysis and death.

Fórmula: C₅₄H₅₆Cl₂N₈O₁₀S₂

Pureza: Min. 95 Area-%

Cor e Forma: White Powder

Peso molecular: 1,112.11 g/mol

Ref: 3D-FC171054

Cloxacillin Benzathine

CAS: 23736-58-5

Fórmula: C₁₉H₁₈ClN₃O₅SC₁₆H₂₀N₂

Peso molecular: 2(435.88) : 240.35

Ref: ST-EA-CP-C155018