CAS 2392-39-4

Fosfato de sódio de dexametasona

Descrição:

Fosfato de sódio de dexametasona é um corticosteroide sintético e um sal de sódio da dexametasona, utilizado principalmente por suas propriedades anti-inflamatórias e imunossupressoras. É caracterizado por sua alta solubilidade em água, o que facilita seu uso em formulações injetáveis. O composto é frequentemente empregado no tratamento de várias condições, incluindo alergias, distúrbios autoimunes e certos tipos de câncer. Fosfato de sódio de dexametasona atua inibindo a liberação de mediadores inflamatórios e modulando as respostas imunológicas. Seus efeitos farmacológicos são atribuídos à sua capacidade de se ligar aos receptores de glicocorticoides, levando a alterações na expressão gênica. A substância é tipicamente administrada por vias intramusculares ou intravenosas, e sua dosagem pode variar com base na condição específica a ser tratada. Efeitos colaterais comuns podem incluir aumento dos níveis de açúcar no sangue, retenção de líquidos e possível supressão da função da glândula adrenal com o uso prolongado. Assim como com todos os corticosteroides, o monitoramento cuidadoso é essencial para mitigar efeitos adversos e garantir a eficácia terapêutica.

Fórmula: C₂₂H₃₀FO₈P·2Na

InChI: InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/t12-,15+,16+,17+,19+,20+,21+,22+;;/m1../s1

Chave InChI: InChIKey=ODEOTKLZVXBMJD-FCJDYXGNSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](F)([C@]4(C)C(CC3)=CC(=O)C=C4)[C@@H](O)C1)[H])(C[C@@H](C)[C@@]2(C(COP(=O)(O)O)=O)O)[H].[Na]

Sinónimos:

• (9R,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
• Ak-Dex
• Baldex
• Colvasone
• Corson
• Corson (pharmaceutical)
• Dalalone
• Decadron phosphate
• Decdan
• Desashock
• Dexabene
• Dexacort
• Dexadreson
• Dexagel
• Dexagro
• Dexamethasone 21-(Disodium Phosphate)
• Dexamethasone Phosphate Disodium
• Dexamethasone Phosphate Sodium
• Dexamethasone Sodium Phosphate
• Dexamethasone disodium phosphate
• Dexamethasone phosphate disodium salt
• Dexamethasone phosphate sodium salt
• Dexamethazone sodium phosphate
• Dezone
• Disodium (11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Phosphate
• Disodium dexamethasone 21-monophosphate
• Disodium dexamethasone 21-phosphate
• Disodium dexamethasone phosphate
• Maxidex Ointment
• Megacort
• Onadron
• Orgadrone
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, sodium salt (1:2), (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-(dihydrogen phosphate) disodium salt
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-phosphate disodium salt
• Sodium dexamethasone phosphate
• Soldesam
• Solu-Deca
• Solu-Decadron
• Spersadex

9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione, 21-(dihydrogen phosphate) disodium salt

CAS: 2392-39-4

Pureza: 98%

Ref: IN-DA003AAJ

Dexamethasone 21-phosphate disodium salt, 98%

CAS: 2392-39-4

Dexamethasone 21-phosphate disodium salt (Dex 21-P), 2392-39-4, is the sodium salt form of dexamethasone, a synthetic corticosteroid with anti-inflammatory properties. Learn more.

Fórmula: C₂₂H₂₈FNa₂O₈P

Pureza: 98%

Cor e Forma: White to pale cream, Crystals or powder or crystalline powder

Peso molecular: 516.41

Ref: 02-J64083

DEXAMETHASONE SODIUM PHOSPHATE CRS

CAS: 2392-39-4

DEXAMETHASONE SODIUM PHOSPHATE CRS

Fórmula: C₂₂H₂₈FNa₂O₈P

Cor e Forma: White. Whitish. Powder.

Peso molecular: 516.4046

Ref: 41-D0720000

DEXAMETHASONE SODIUM PHOSPHATE FOR PEAK IDENTIFICATION CRS

CAS: 2392-39-4

DEXAMETHASONE SODIUM PHOSPHATE FOR PEAK IDENTIFICATION CRS

Fórmula: C₂₂H₂₈FNa₂O₈P

Peso molecular: 516.4046

Ref: 41-Y0001477

Dexamethasone sodium phosphate

CAS: 2392-39-4

Dexamethasone sodium phosphate

Fórmula: C₂₂H₂₈FNa₂O₈P

Pureza: 88.6%

Cor e Forma: White

Peso molecular: 516.13012

Ref: 47-108

DEXAMETHASONE SODIUM PHOSPHATE RS

CAS: 2392-39-4

DEXAMETHASONE SODIUM PHOSPHATE RS

Fórmula: C₂₂H₂₈FNa₂O₈P

Peso molecular: 516.4046

Ref: 41-ICRS0270

Dexamethasone Sodium Phosphate

CAS: 2392-39-4

Halogenated derivatives of adrenal cortical hormones

Fórmula: C₂₂H₂₈FNa₂O₈P

Cor e Forma: White Yellow Powder

Peso molecular: 516.13012

Ref: 45-1177032

Dexamethasone Phosphate disodium

CAS: 2392-39-4

Dexamethasone Phosphate disodium (EGP437. Dex-Phos) is a water-soluble form of the synthetic glucocorticoid dexamethasone.

Fórmula: C₂₂H₂₈FNa₂O₈P

Pureza: 99.76% - 99.848%

Cor e Forma: White To Off White Powder

Peso molecular: 516.4

Ref: TM-T0947L

Dexamethasone 21-phosphate disodium salt, USP grade

CAS: 2392-39-4

Fórmula: C₂₂H₂₈FNa₂O₈P

Pureza: ≤ 0.1%

Cor e Forma: White powder

Peso molecular: 516.40

Ref: 7W-GL6086

Dexamethasone Phosphate disodium

CAS: 2392-39-4

Dexamethasone Phosphate disodium

Pureza: ≥98%

Peso molecular: 516.4g/mol

Ref: 54-BUP16045

Dexamethasone sodium phosphate

Produto Controlado

CAS: 2392-39-4

Fórmula: C₂₂H₂₈FO₈PNa

Cor e Forma: Neat

Peso molecular: 516.40

Ref: 04-C12170450

Dexamethasone Sodium Phosphate

Produto Controlado

CAS: 2392-39-4

Fórmula: C₂₂H₂₈FO₈PNa

Cor e Forma: Neat

Peso molecular: 516.40

Ref: 86-MM0210.00

Dexamethasone 21-phosphate disodium salt

CAS: 2392-39-4

Fórmula: C₂₂H₂₈FNa₂O₈P

Pureza: 97.0 - 103.0 % (anhydrous, solvent-free basis)

Cor e Forma: White to off-white powder

Peso molecular: 516.40

Ref: 7W-GX3546

Dexamethasone Sodium phosphate

CAS: 2392-39-4

Fórmula: C₂₂H₂₈FO₈P(Na)

Peso molecular: 470.4 : 2(23.0)

Ref: ST-EA-CP-D105000

Betamethasone Sodium Phosphate Impurity B

CAS: 2392-39-4

Fórmula: C₂₂H₂₈FO₈P(Na)

Peso molecular: 470.43 : 2(23.0)

Ref: ST-EA-CP-B92002

Dexamethasone Sodium Phosphate

Produto Controlado

CAS: 2392-39-4

Stability Hygroscopic
Applications Dexamethasone Sodium Phosphate is an inducer of apoptosis and inhibitor of the sodium phosphate symporter.

Fórmula: C₂₂H₂₈FO₈P·2Na

Cor e Forma: Neat

Peso molecular: 516.4

Ref: TR-D298898

Dexamethasone sodium phosphate

CAS: 2392-39-4

Dexamethasone sodium phosphate is a water-soluble glucocorticosteroid used in the treatment of inflammation and pain. In a rabbit model, the inclusion of dexamethasone sodium phosphate into liposomes has improved its delivery to the eye compartments (Al-Muhammed, 1996). To improve the acceptability by paediatric patients, dexamethasone sodium phosphate has been tested in formulations with sweeteners and chocolate (Synaridou, 2020). A pollutant of hospital wastewater, dexamethasone sodium phosphate is degraded by Pseudomonas alcaligenes during bioremediation (Yi, 2014).

Fórmula: C₂₂H₂₈FO₈P•Na₂

Pureza: Min. 97 Area-%

Cor e Forma: Powder

Peso molecular: 516.41 g/mol

Ref: 3D-FD31952

disodium (1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-2,13,15-trimethyl-14-[2-(phosphonatooxy)acetyl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one

CAS: 2392-39-4

Fórmula: C₂₂H₂₈FNa₂O₈P

Pureza: 98.0%

Cor e Forma: Solid

Peso molecular: 516.41

Ref: 10-F358382

Dexamethasone 21-phosphate disodium salt

CAS: 2392-39-4

Dexamethasone is a high-quality reagent that belongs to the group of complex compounds. It is a fine chemical with CAS No. 2392-39-4 and can be used as an intermediate in the production of various other chemicals, such as speciality chemicals and research chemicals. Dexamethasone has been used as a building block for the synthesis of many biologically active molecules, including corticosteroids and antihistamines. Dexamethasone also acts as a versatile building block for reactions involving alcohols, amines, carboxylic acids, esters, nitriles, thiols, sulfides and sulfones.

Fórmula: C₂₂H₂₈FNa₂O₈P

Peso molecular: 516.40 g/mol

Ref: 3D-Q-200941

Dexamethasone Sodium Phosphate

CAS: 2392-39-4

Cor e Forma: Neat

Ref: 61-FOR0210.00