CAS 2415-24-9

Catalpol

Descrição:

Catalpol, com o número CAS 2415-24-9, é um glicosídeo iridoide que ocorre naturalmente, encontrado principalmente em várias espécies de plantas, particularmente no gênero Rehmannia. É caracterizado por sua estrutura química, que inclui um grupo de glicose ligado a um núcleo iridoide. Catalpol é conhecido por suas potenciais propriedades farmacológicas, incluindo efeitos anti-inflamatórios, antioxidantes e neuroprotetores. Tem sido estudado por seu papel na medicina tradicional, particularmente em remédios herbais chineses, onde se acredita que apoia a saúde renal e melhora a vitalidade geral. O composto exibe solubilidade em solventes polares, o que é típico para glicosídeos, e sua estabilidade pode ser influenciada por fatores como pH e temperatura. A pesquisa sobre Catalpol continua a explorar seus mecanismos de ação e potenciais aplicações terapêuticas, tornando-o um assunto de interesse tanto em farmacognosia quanto em química medicinal.

Fórmula: C₁₅H₂₂O₁₀

InChI: InChI=1S/C15H22O10/c16-3-6-9(19)10(20)11(21)14(23-6)24-13-7-5(1-2-22-13)8(18)12-15(7,4-17)25-12/h1-2,5-14,16-21H,3-4H2/t5-,6-,7-,8+,9-,10+,11-,12+,13+,14+,15-/m1/s1

Chave InChI: InChIKey=LHDWRKICQLTVDL-PZYDOOQISA-N

SMILES: C(O)[C@@]12[C@@]3([C@]([C@H](O)[C@@]1(O2)[H])(C=CO[C@H]3O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[H])[H]

Sinónimos:

• (1AS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl-beta-D-glucopyranoside
• (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
• (1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-2-yl beta-D-glucopyranoside
• 6-Hydroxy-1A-(Hydroxymethyl)-1A,1B,2,5A,6,6A-Hexahydrooxireno[4,5]Cyclopenta[1,2-C]Pyran-2-Yl Hexopyranoside
• 7,8-Epoxyaucubin
• Aucubin 7,8-epoxide
• Catalpinoside
• Catalposide, des-p-hydroxybenzoyl-
• Catapol
• De(p-hydroxybenzoyl)catalposide
• beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy- 1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, (1aS-(1a-alpha,1b-beta,2-beta,5a-beta,6-beta,6a-alpha))-
• beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, (1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• Catalpol
• β-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl

Catalpol

CAS: 2415-24-9

Catalpol analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₁₅H₂₂O₁₀

Pureza: (HPLC) ≥99%

Cor e Forma: Powder

Peso molecular: 362.34

Ref: 11-0233S

CATALPOL CRS

CAS: 2415-24-9

CATALPOL CRS

Ref: 41-Y0002142

(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-D-glucopyranoside

CAS: 2415-24-9

Fórmula: C₉H₁₆O₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 188.2209

Ref: IN-DA0039M9

Catalpol

CAS: 2415-24-9

Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.

Fórmula: C₁₅H₂₂O₁₀

Pureza: 99.74% - 99.89%

Cor e Forma: Powder

Peso molecular: 362.33

Ref: TM-T2780

Catalpol

CAS: 2415-24-9

Catalpol

Pureza: ≥98%

Peso molecular: 362.33g/mol

Ref: 54-BUP00175

Catalpol

CAS: 2415-24-9

Fórmula: C₁₅H₂₂O₁₀

Pureza: ≥ 96.5%

Cor e Forma: White, off-white or faint brown powder

Peso molecular: 362.33

Ref: 7W-GC8147

Catalpol

CAS: 2415-24-9

Catalpol

Pureza: 98%

Peso molecular: 362.33g/mol

Ref: 54-OR1026446

Catalpol

CAS: 2415-24-9

Catalpol, an iridoid glucoside, has been reported to inhibit apoptosis of neuron and endothelial cells; the pretreatment of H9c2 cells with catalpol can be against H 2 O 2 -induced apoptosis, and the protective effect of catalpol involves the mitochondrial-dependent caspase pathway and is associated with increased Bcl-2 and decreased Bax expression.

Fórmula: C₁₅H₂₂O₁₀

Pureza: 95%~99%

Cor e Forma: Powder

Peso molecular: 362.331

Ref: BP-BP0321

Catalpol

CAS: 2415-24-9

Fórmula: C₁₅H₂₂O₁₀

Pureza: >95.0%(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 362.33

Ref: 3B-C3494

Catalpol

CAS: 2415-24-9

Natural glycoside

Fórmula: C₁₅H₂₂O₁₀

Pureza: ≥ 98.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 362.33

Ref: 5G-89595

Catapol

CAS: 2415-24-9

Applications Catapol is an iridoid glucoside that has been shown to alleviate neuropathic pain.
References Gong, N. et al.: Neuripharmacol., 83, 31 (2014); Liu, Z. et al.: Curr. Bioact. COmp., 9, 306 (2013);

Fórmula: C₁₅H₂₂O₁₀

Cor e Forma: White To Off White

Peso molecular: 362.33

Ref: TR-C215150

Catalpol

CAS: 2415-24-9

Catalpol is an iridoid glycoside, which is a natural compound isolated primarily from the roots of the plant *Rehmannia glutinosa*. This compound is known for its various bioactive properties, functioning predominantly through its ability to modulate antioxidant pathways, regulate inflammatory responses, and exert neuroprotective effects. These modes of action are attributed to its capacity to influence cellular signaling pathways, such as the PI3K/Akt pathway, and to interact with reactive oxygen species (ROS), thereby mitigating oxidative stress.

Fórmula: C₁₅H₂₂O₁₀

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 362.33 g/mol

Ref: 3D-MC08278

Catalpol

CAS: 2415-24-9

Pureza: 98%

Peso molecular: 362.331

Ref: 10-F979677