CAS 24280-93-1

Ácido micofenólico

Descrição:

Ácido micofenólico é um composto orgânico com a fórmula química C17H20O6 e é classificado como um imunossupressor seletivo. É derivado principalmente do fungo Penicillium e é conhecido por seu papel na inibição da enzima inosina monofosfato desidrogenase (IMPDH), que é crucial na via de síntese de novo de nucleotídeos de purina. Esse mecanismo o torna particularmente eficaz na prevenção da rejeição de transplantes de órgãos e no tratamento de doenças autoimunes. Ácido micofenólico aparece como um pó cristalino branco a off-white e é solúvel em solventes orgânicos como etanol e dimetilsulfóxido, mas tem solubilidade limitada em água. Suas propriedades farmacológicas incluem efeitos anti-inflamatórios, e é frequentemente usado em combinação com outros imunossupressores para aumentar a eficácia e reduzir o risco de rejeição em pacientes transplantados. No entanto, também pode levar a efeitos colaterais, como distúrbios gastrointestinais e um aumento do risco de infecções devido à sua ação imunossupressora. O monitoramento adequado e os ajustes de dosagem são essenciais durante seu uso terapêutico.

Fórmula: C₁₇H₂₀O₆

InChI: InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+

Chave InChI: InChIKey=HPNSFSBZBAHARI-RUDMXATFSA-N

SMILES: CC1=C2C(=C(O)C(C/C=C(/CCC(O)=O)\C)=C1OC)C(=O)OC2

Sinónimos:

• (4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid
• (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate
• (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
• (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid
• 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)-
• 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-
• 4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-, (E)-
• 6-(4-Hydroxy-6-Methoxy-7-Methyl-3-Oxo-1,3-Dihydro-2-Benzofuran-5-Yl)-4-Methylhex-4-Enoic Acid
• Acide Mycophenolique
• Acido Micofenolico
• Lilly 68618
• MPA
• Melbex
• Mycophenolic Acid From Penicillium Brevi-Compactum
• Mycophenolic Acid From Penicillium*Brevi-Compactu
• Mycophenolinsaure
• Nsc 129185

Mycophenolic Acid

CAS: 24280-93-1

Fórmula: C₁₇H₂₀O₆

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 320.34

Ref: 3B-M2216

Mycophenolic acid, 98%

CAS: 24280-93-1

It is used as a small molecule IMPDH inhibitor. mycophenolic Acid is used as an immunosuppressive agent with antiviral and antitumor effects. It potently inhibits inosine monophosphate dehydrogenase, thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. It also reversibly

Fórmula: C₁₇H₂₀O₆

Pureza: 98%

Peso molecular: 320.34

Ref: 02-J61905

Mycophenolic Acid

CAS: 24280-93-1

Cor e Forma: Neat

Ref: 61-FOR1001.06

4-Hexenoic acid,6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)-

CAS: 24280-93-1

Fórmula: C₁₇H₂₀O₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 320.3371

Ref: IN-DA00I4O6

Mycophenolic acid

CAS: 24280-93-1

Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.

Fórmula: C₁₇H₂₀O₆

Pureza: 98.79% - 99.77%

Cor e Forma: Solid

Peso molecular: 320.34

Ref: TM-T1335

Mycophenolic acid

CAS: 24280-93-1

Mycophenolic acid

Pureza: ≥98%

Peso molecular: 320.34g/mol

Ref: 54-BUP17030

Mycophenolic Acid (Mycophenolate Mofetil EP Impurity F)

CAS: 24280-93-1

Fórmula: C₁₇H₂₀O₆

Cor e Forma: White To Off-White Solid

Peso molecular: 320.34

Ref: 4Z-M-163

Mycophenolic acid

CAS: 24280-93-1

Mycophenolic acid

Cor e Forma: White Powder

Peso molecular: 320.34g/mol

Ref: 54-BI1535

Mycophenolic acid

CAS: 24280-93-1

Fórmula: C₁₇H₂₀O₆

Pureza: ≥ 98.0%

Cor e Forma: White to off-white crystalline powder

Peso molecular: 320.34

Ref: 7W-GA8210

Mycophenolic acid 100 µg/mL in Acetonitrile

Produto Controlado

CAS: 24280-93-1

Fórmula: C₁₇H₂₀O₆

Cor e Forma: Single Solution

Peso molecular: 320.34

Ref: 04-A15391000AL-100

Mycophenolic acid

Produto Controlado

CAS: 24280-93-1

Fórmula: C₁₇H₂₀O₆

Cor e Forma: Neat

Peso molecular: 320.34

Ref: 04-C15391000

(4E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic Acid (Mycophenolic Acid)

CAS: 24280-93-1

Cor e Forma: Neat

Ref: 86-MM1001.06

Mycophenolic Acid

Produto Controlado

CAS: 24280-93-1

Applications An antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.Environmental contaminants; Food contaminants
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),

Fórmula: C₁₇H₂₀O₆

Cor e Forma: White To Off-White

Peso molecular: 320.34

Ref: TR-M831500

Mycophenolate Mofetil EP Impurity F

CAS: 24280-93-1

Fórmula: C₁₇H₂₀O₆

Peso molecular: 320.34

Ref: ST-EA-CP-M27006

Mycophenolic acid - Bio-X ™

CAS: 24280-93-1

Mycophenolic acid is an immunosuppressant metabolite present in drug formulations that are used to prevent rejections after organ transplants. Mycophenolic acid is a selective inhibitor of inosine monophosphate dehydrogenase (IMPDH) which blocks the conversion of inosine-5-phosphate and xanthine-5-phosphate to guanosine-5-phosphate. This drug inhibits de novo purine biosynthesis. It has also shown to have antibacterial and antifungal properties.

Fórmula: C₁₇H₂₀O₆

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 320.34 g/mol

Ref: 3D-BM164624

Mycophenolic acid

CAS: 24280-93-1

Mycophenolic acid is a guanosine monophosphate synthesis pathway blocker. It selectively inhibits inosine monophosphate dehydrogenase (IMPDH) which blocks the conversion of inosine-5-phosphate and xanthine-5-phosphate to guanosine-5-phosphate. This drug inhibits de novo purine biosynthesis. Mycophenolic acid is an immunosuppressant metabolite present in drug formulations that are used to prevent rejections after organ transplants. It has also shown to have antibacterial and antifungal properties.

Fórmula: C₁₇H₂₀O₆

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 320.34 g/mol

Ref: 3D-FM15781

Mycophenolic Acid

CAS: 24280-93-1

M02087 - Mycophenolic Acid

Fórmula: C₁₇H₂₀O₆

Pureza: 98%

Cor e Forma: Solid, White to off-white powder

Peso molecular: 320.341

Ref: 10-M02087

Mycophenolic Acid-13C-d3

Produto Controlado

CAS: 24280-93-1

Applications Mycophenolic Acid-13C-d3 is a labelled Mycophenolic Acid, an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.
References Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),

Fórmula: CC₁₆D₃H₁₇O₆

Cor e Forma: Neat

Peso molecular: 324.348

Ref: TR-M831503

Mycophenolic Acid ((4E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic Acid)

CAS: 24280-93-1

Aromatic lactones used as drugs

Fórmula: C₁₇H₂₀O₆

Cor e Forma: White Crystalline Solid

Peso molecular: 320.12599

Ref: 45-1A06830