CAS 249537-73-3

H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-Oh

Descrição:

A substância referida como "H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-Oh" com o número CAS 249537-73-3 é um peptídeo, especificamente uma sequência de aminoácidos ligados por ligações peptídicas. Este composto apresenta uma variedade de aminoácidos, incluindo metionina (Met), alanina (Ala), glicina (Gly), prolina (Pro), histidina (His), valina (Val), isoleucina (Ile), treonina (Thr) e ácido glutâmico (Glu). A presença de prolina sugere rigidez estrutural, enquanto as diversas cadeias laterais dos outros aminoácidos contribuem para sua potencial atividade biológica e interações. O prefixo "H-" indica que o peptídeo está provavelmente em sua forma protegida, enquanto o "Oh" no final sugere a presença de um grupo hidroxila, que pode influenciar sua solubilidade e reatividade. Peptídeos como este podem desempenhar papéis significativos em processos biológicos, incluindo sinalização, atividade enzimática e comunicação celular, tornando-os de interesse em campos como bioquímica e farmacologia.

NFAT Inhibitor

CAS: 249537-73-3

The flow of information from calcium-mobilizing receptors to nuclear factor of activated T cells (NFAT)-dependent genes is critically dependent on interaction between the phosphatase calcineurin and the transcription factor NFAT. The high-affinity calcineurin-binding peptide potently inhibited NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells, without affecting the expression of other cytokines that require calcineurin but not NFAT. NFAT inhibitors may be useful in treating chronic ailments such as myocardial hypertrophy, allergy, arthritis, and autoimmune disease.

Fórmula: C₇₅H₁₁₈N₂₀O₂₂S

Pureza: 98.2%

Cor e Forma: White Powder

Peso molecular: 1683.95

Ref: 01-4034010

NFAT Inhibitor-1

CAS: 249537-73-3

Fórmula: C₇₅H₁₂₀N₂₀O₂₂S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1685.9411

Ref: IN-DA00BERD

NFAT Inhibitor

CAS: 249537-73-3

Fórmula: C₇₅H₁₁₈N₂₀O₂₂S

Peso molecular: 1683.93

Ref: 7W-GL0293

NFAT Inhibitor

CAS: 249537-73-3

NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT.

Fórmula: C₇₅H₁₁₈N₂₀O₂₂S

Pureza: 98.26%

Cor e Forma: Solid

Peso molecular: 1683.93

Ref: TM-TP1015

NFAT Inhibitor

CAS: 249537-73-3

NFAT Inhibitor

Fórmula: C₇₅H₁₁₈N₂₀O₂₂S

Pureza: 98% (Typical Value in Batch COA)

Cor e Forma: white solid

Peso molecular: 1,797.95g/mol

Ref: 54-BISN0319

NFAT Inhibitor trifluoroacetate salt

CAS: 249537-73-3

NFAT Inhibitor trifluoroacetate salt H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu (NFAT) is an inhibitor drug that has been shown to inhibit the nuclear factor of activated T cells (NFAT). NFAT is a transcriptional regulator that controls the expression of inflammatory genes in macrophages and other cell types. NFAT inhibitors have been shown to be effective for treating bowel diseases, such as ulcerative colitis and Crohn's disease, by inhibiting the activation of macrophages. NFAT inhibitors are also used in vitro as a tool for studying cellular signaling pathways. The most common type of NFAT inhibitor is fluconazole, which blocks calcineurin activity and prevents the activation of NFAT. However, other types of inhibitors are being developed, including mmp9 activity or

Fórmula: C₇₅H₁₁₈N₂₀O₂₂S

Pureza: Min. 95%

Peso molecular: 1,683.93 g/mol

Ref: 3D-FN109384