CAS 25679-24-7

fragmento de colecistoquinina 26-33 amida*não sulfatado

Descrição:

O fragmento 26-33 da colecistoquinina, não sulfatado, é um peptídeo derivado da molécula maior de colecistoquinina (CCK), que desempenha um papel crucial na digestão e na regulação do apetite. Este fragmento específico consiste em uma sequência de aminoácidos que estão envolvidos na estimulação da contração da vesícula biliar e na promoção da liberação de enzimas digestivas do pâncreas. A forma não sulfatada indica que carece de modificações de sulfato, o que pode influenciar sua atividade biológica e interações com receptores. O número CAS 25679-24-7 identifica de forma única este composto em bancos de dados químicos, facilitando seu estudo e aplicação na pesquisa. Caracteristicamente, este peptídeo é solúvel em água e exibe atividade biológica em concentrações nanomolares, tornando-o significativo em processos fisiológicos. Seu papel no sistema gastrointestinal e as potenciais implicações na regulação do apetite e saciedade o tornam um assunto de interesse tanto na pesquisa farmacológica quanto nutricional. Compreender sua estrutura e função pode fornecer insights sobre abordagens terapêuticas para distúrbios digestivos e manejo da obesidade.

Fórmula: C₄₉H₆₂N₁₀O₁₃S₂

InChI: InChI=1/C49H62N10O13S2/c1-73-18-16-34(55-47(70)37(21-28-12-14-30(60)15-13-28)58-44(67)32(50)23-41(62)63)45(68)53-26-40(61)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(71)56-35(17-19-74-2)46(69)59-39(24-42(64)65)49(72)57-36(43(51)66)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52,60H,16-24,26,50H2,1-2H3,(H2,51,66)(H,53,68)(H,54,61)(H,55,70)(H,56,71)(H,57,72)(H,58,67)(H,59,69)(H,62,63)(H,64,65)

SMILES: CSCCC(C(=NCC(=NC(Cc1c[nH]c2ccccc12)C(=NC(CCSC)C(=NC(CC(=O)O)C(=NC(Cc1ccccc1)C(=N)O)O)O)O)O)O)N=C(C(Cc1ccc(cc1)O)N=C(C(CC(=O)O)N)O)O

Sinónimos:

• Cholecystokinin Octapeptide (desulfated)
• H-Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2
• N-[(2S)-2-hydrazino-3-phenylpropanoyl]-L-alpha-aspartyl-L-methionyl-L-tryptophylglycyl-N-[(1S,4S)-4-amino-5-carboxy-1-(4-hydroxybenzyl)-2,3-dioxopentyl]-L-methioninamide
• Alpha-Aspartyltyrosylmethionylglycyltryptophylmethionyl-Alpha-Aspartylphenylalaninamide

Cholecystokinin Octapeptide (desulfated)

CAS: 25679-24-7

Bachem ID: 4003323.

Fórmula: C₄₉H₆₂N₁₀O₁₃S₂

Pureza: 98.1%

Cor e Forma: White Lyophilisate

Peso molecular: 1063.22

Ref: 01-4003323

Cholecystokinin Octapeptide, desulfated

CAS: 25679-24-7

Cholecystokinin Octapeptide, desulfated

Pureza: ≥95%

Peso molecular: 1063.21g/mol

Ref: 54-BUP21237

Cholecystokinin Octapeptide, desulfated

CAS: 25679-24-7

Cholecystokinin Octapeptide, desulfated (CCK Octapeptide, non-sulfated) is an octapeptide composed of 8 amino acids from cholecystokinin-8.

Fórmula: C₄₉H₆₂N₁₀O₁₃S₂

Pureza: 97.12%

Cor e Forma: Solid

Peso molecular: 1063.21

Ref: TM-TP2204

CCK octapeptide Cholecystokinin (26-33)

CAS: 25679-24-7

The octapeptide cholecystokinin (26-33), known as CCK-8, has the full biological activity of the full-length cholecystokinin (CCK). CCK acts as a hormone and neurotransmitter and is found in the GI and central nervous systems. CCK-8 is a satiety peptide that inhibits food intake.CCK-8 can also inhibit amanitin uptake into hepatocytes.

Fórmula: C₄₉H₆₂N₁₀O₁₃S₂

Peso molecular: 1,063.21 g/mol

Ref: 3D-CRB1000237

CCK-Octapeptide (26-33) (Non-Sulfated Form)

CAS: 25679-24-7

CCK-Octapeptide (26-33) is a peptide that is a member of the cholecystokinin family of peptides. CCK-Octapeptide (26-33) is an activator of the CCK receptor and can be used for research purposes. This peptide has been shown to inhibit ion channels, which are proteins that regulate the flow of ions across cell membranes, and may be used as a pharmacological tool or research tool.

Fórmula: C₄₉H₆₂N₁₀O₁₃S₂

Pureza: Min. 95%

Peso molecular: 1,063.2 g/mol

Ref: 3D-PCK-4087-V

Cholecystokinin Octapeptide (desulfated)

CAS: 25679-24-7

Cholecystokinin octapeptide (CCK-8) is a peptide hormone that is secreted from the pancreas. It is a conjugate of CCK and desulfated cholinesterase, which has been shown to have surfactant properties. The concentration-response curves for CCK-8 are biphasic, with an initial increase in contractility followed by a decrease. This response is caused by activation of both the B2 and B1 receptors in the paraventricular nucleus of the hypothalamus and subsequently release of pancreatic enzymes into the bloodstream. CCK-8 has also been shown to stimulate protein synthesis in gland cells such as those found in the pancreas.

Fórmula: C₄₉H₆₂N₁₀O₁₃S₂

Pureza: Min. 95%

Peso molecular: 1,063.21 g/mol

Ref: 3D-FC108598