CAS 2568273-82-3

PROTAC SMARCA2/4-degrader-29

CAS: 2568273-82-3

PROTAC SMARCA2/4-degrader-29 (Compound I-279) serves as a degrader for the catalytic subunits SMARCA2 and SMARCA4 of the SWI/SNF complex. In A549 cells, this compound effectively degrades SMARCA2 with a DC50 value of less than 100 nM, and similarly degrades SMARCA4 in MV411 cells with a DC50 under 100 nM.

Fórmula: C₄₄H₅₁N₁₁O₄

Cor e Forma: Solid

Peso molecular: 797.95

Ref: TM-T200058