CAS 26172-55-4

5-Cloro-2-metil-4-isotiazolin-3-ona

Descrição:

5-Cloro-2-metil-4-isotiazolin-3-ona, comumente referido como CMIT, é um composto orgânico sintético usado principalmente como biocida e conservante em várias aplicações industriais, incluindo cosméticos, tintas e tratamento de água. É caracterizado por sua estrutura de isotiazolinona, que contribui para suas propriedades antimicrobianas, tornando-o eficaz contra bactérias, fungos e algas. O CMIT é tipicamente um líquido amarelo pálido a incolor com um odor característico. É solúvel em água e solventes orgânicos, o que aumenta sua utilidade em formulações. O composto é conhecido por sua estabilidade sob uma variedade de condições de pH, embora possa ser sensível à luz e ao calor. Considerações de segurança são importantes, pois o CMIT pode ser um irritante para a pele e o sistema respiratório, e tem sido associado a reações alérgicas em alguns indivíduos. Diretrizes regulatórias frequentemente ditam seus limites de concentração em produtos de consumo para mitigar potenciais riscos à saúde. No geral, o CMIT é valorizado por sua eficácia em preservar produtos e prevenir o crescimento microbiano, mas requer manuseio e uso cuidadosos.

Fórmula: C₄H₄ClNOS

InChI: InChI=1S/C4H4ClNOS/c1-6-4(7)2-3(5)8-6/h2H,1H3

Chave InChI: InChIKey=DHNRXBZYEKSXIM-UHFFFAOYSA-N

SMILES: O=C1N(C)SC(Cl)=C1

Sinónimos:

• 1-(4-Chlorophenyl)-3-(3,4-Dichlorophenyl)Urea
• 2-Methyl-5-Chloro Isothiazolinone
• 2-Methyl-5-chloro-3-isothiazolone
• 2-Methyl-5-chloroisothiazolin-3-one
• 3(2H)-Isothiazolone, 5-chloro-2-methyl-
• 4-Isothiazolin-3-one, 5-chloro-2-methyl-
• 5-Chlor-2-methyl-2H-isothiazol-3-on
• 5-Chloride-2-Methyl-4-Isothiazoline-3-Ketone
• 5-Chloro-2-methyl-2H-isothiazol-3-one
• 5-Chloro-2-methyl-2H-isothiazolin-3-one
• 5-Chloro-2-methyl-3(2H)-isothiazolinone
• 5-Chloro-2-methyl-3(2H)-isothiazolone
• 5-Chloro-2-methyl-3-isothiazolone
• 5-Chloro-2-methyl-4-isothiazolin-3-on
• 5-Chloro-2-methyl-4-isothiazoline-3-ketone
• 5-Chloro-2-methyl-4-isothiazoline-3-one
• 5-Chloro-2-methyl-Isothiazolin-3-one
• 5-Chloro-2-methylisothiazol-3-one
• 5-Chloro-2-methylisothiazolin-3-one
• 5-Chloro-N-methylisothiazolin-3-one
• 5-Chloro-N-methylisothiazolone
• 5-Choro-2-methyl-4-isothiazolin-3-one/2-methyle-4-isothiazolin-3-one
• 5-chloro-2-methyl-1,2-thiazol-3(2H)-one
• 5-chloro-2-methyl-1,2-thiazol-3(2H)-one hydrochloride (1:1)
• 5-chloro-2-methyl-2H-isothiazole-3-one
• 5-cloro-2-metil-2H-isotiazol-3-ona
• A 33
• A 33 (bactericide)
• Acticide
• Acticide C 1
• Algucid CH50
• Amerstat 250
• Bioace
• CIT
• Chloromethyl Isothiazolone
• Cmit
• Cmit Isothiazolone
• Euxyl K 100
• Fennosan IT 21
• GR 856 Izolin
• Grotan K
• Grotan TK2
• HS 818 (antiseptic)
• Hs 818
• Isothiazol(2H)-3-One, 5-Chloro-2-Methyl-
• Isothiazolinone Biocidescides
• Isothiazolinones
• Isothiazolone,5-chloro-2-methyl-
• Kathon CG 5243
• Kathon CJ 1
• Kathon DP
• Kathon IXE
• Kathon LX
• Kathon UT
• Kathon WT
• Mci/Mi
• Mergal K7
• Metat GT
• Metatin GT
• Methyl Chloroisothiazolinone
• Methylchloroisothiazolinone
• Methylchloroisothiazolinone/Methylisothiazolinone
• Mitco CC 32 L
• N-Methyl-5-chloroisothiazolin-3-one
• N-Methyl-5-chloroisothiazolone
• P3 Multan D
• Paretol
• Parmetol DF 35, -DF 12, -A23, -K50, -K40, -DF 18
• Piror P109
• Special Mx 323
• T 360

5-Chloro-2-methyl-4-isothiazolin-3-one, tech grade, >14% in water. CMI/MI >2.0

CAS: 26172-55-4

Fórmula: C₄H₄ClNOS

Pureza: 2.5%

Cor e Forma: Liquid

Peso molecular: 149.5987

Ref: IN-DA00384S

Plant preservative mixture

CAS: 26172-55-4

Plant preservative mixture

Fórmula: C₄H₄ClNOS

Cor e Forma: liquid

Peso molecular: 149.59866g/mol

Ref: 54-P820

5-Chloro-2-methyl-4-isothiazolin-3-one

CAS: 26172-55-4

Pureza: CMIT: 10.0 - 12.0 %

Cor e Forma: Clear, yellow to green liquid

Peso molecular: -

Ref: 7W-GK5171

Methyl Chloroisothiazolinone

CAS: 26172-55-4

Fórmula: C₄H₄ClNOS

Cor e Forma: White To Off-White Solid

Peso molecular: 149.59

Ref: 4Z-I-491

5-Chloro-2-methyl-4-isothiazolin-3-one 100 µg/mL in Acetonitrile

CAS: 26172-55-4

Fórmula: C₄H₄ClNOS

Cor e Forma: Single Solution

Peso molecular: 149.60

Ref: 04-A11433000AL-100

N-Methyl-5-chloroisothiazolone (5-Chloro-2-methyl-4-isothiazolin-3-one)

CAS: 26172-55-4

Cor e Forma: Neat

Ref: 86-MM0877.06

5-Chloro-2-methyl-4-isothiazolin-3-one

Produto Controlado

CAS: 26172-55-4

Fórmula: C₄H₄ClNOS

Cor e Forma: Neat

Peso molecular: 149.60

Ref: 04-CA11433000

5-Chloro-2-methyl-3-isothiazolone (~90%)

Produto Controlado

CAS: 26172-55-4

Stability Hygroscopic
Applications A isothiazolidin-3-one derivative as antimicrobial. It was tested for inhibition of PCAF activity. 5-Chloroisothiazolinones showed the most potent inhibition of PCAF.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sadhale, P.P., et al.: J. Biol. Chem., 279, 33716 (2004), Thomsen, R., et al.: J. Med. Chem., 49, 3315 (2006),

Fórmula: C₄H₄ClNOS

Pureza: ~90%

Cor e Forma: Off-White

Peso molecular: 149.60

Ref: TR-C369235

5-Chloro-2-methyl-4-isothiazolin-3-one, tech grade, >14% in water. CMI/MI >2.0

CAS: 26172-55-4

Fórmula: C₄H₄ClNOS

Pureza: 68.0%

Cor e Forma: Liquid

Peso molecular: 149.59

Ref: 10-F209044

5-Chloro-2-methyl-3-isothiazolone - Active Ingredient >14%, CMI/MI 2.5 - 4.0

CAS: 26172-55-4

5-Chloro-2-methyl-3-isothiazolone (CMIT) is a highly water-soluble apoptotic agent and preservative with numerous applications. It is used in anti-microbial coatings, latex formulations, hydraulic fracturing fluids, pesticides and cosmetics. CMIT in conjunction with 2-methyl-4-isothiazolin-3-one (MIT) is marketed as Kathon. CMIT is also an allergen. CMIT is active against gram-positive and gram-negative bacteria, yeasts and fungi. CMIT is believed to form mixed disulfides with protein thiol groups which then undergo thiol-disulfide exchange reactions to give mixed protein thiol disulfides leading to cell apoptosis and necrosis.

Fórmula: C₄H₄ClNOS

Cor e Forma: Yellow Clear Liquid

Peso molecular: 149.6 g/mol

Ref: 3D-FC20025