CAS 2627-69-2

AICAr

Descrição:

AICAr, ou 5-aminoimidazol-4-carboxamida ribonucleotídeo, é um composto químico que desempenha um papel significativo no metabolismo celular, particularmente na via de biossíntese de purinas. É um precursor de nucleotídeos que está envolvido na síntese de adenosina monofosfato (AMP). AICAr é conhecido por seus efeitos potenciais no metabolismo energético celular e tem sido estudado por seu papel na ativação da quinase de proteínas ativada por AMP (AMPK), que é crucial para regular a homeostase energética. O composto é frequentemente investigado no contexto de distúrbios metabólicos, fisiologia do exercício e potenciais aplicações terapêuticas para condições como obesidade e diabetes tipo 2. AICAr é tipicamente caracterizado por sua estrutura molecular, que inclui um anel de imidazol e um componente de ribonucleotídeo. Seu número CAS, 2627-69-2, é um identificador único que facilita a identificação e o estudo deste composto na literatura científica e em bancos de dados. No geral, AICAr é uma molécula significativa em bioquímica com implicações para a saúde e o manejo de doenças.

Fórmula: C₉H₁₄N₄O₅

InChI: InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1

Chave InChI: InChIKey=RTRQQBHATOEIAF-UUOKFMHZSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(N)=C(C(N)=O)N=C2

Sinónimos:

• 1-Ribosyl-4-carboxamido-5-aminoimidazole
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-5-amino-4-imidazolecarboxamide
• 1H-Imidazole-4-carboxamide, 5-amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 5-Amino-1-beta-ribofuranosyl-imidazole-4-carboxamide
• 5-Amino-1-ribosyl-4-imidazolecarboxamide
• 5-Amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-imidazole-4-carboxamide
• 5-Amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosylimidazole-4-carboxamide
• 5-Amino-1beta-D-ribofuranosylimidazole-4-carboxamide
• 5-Amino-4-imidazolecarboxamide ribofuranoside
• 5-Amino-4-imidazolecarboxamide riboside
• 5-Aminoimidazole-4-carboxamid-1-β-<span class="text-smallcaps">D</span>-ribofuranoside
• 5-Aminoimidazole-4-carboxamide 1-(β-<span class="text-smallcaps">D</span>-ribofuranoside)
• 5-Aminoimidazole-4-carboxamide ribonucleoside
• 5-Aminoimidazole-4-carboxamide riboside
• 5-Aminoimidazole-4-carboxamide-1-§-D-Ribofuranoside
• 5-amino-1-(beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide
• AIC-Riboside
• AICA-riboside
• Acadra
• Aicar
• Arasine
• Gp 1-110
• Imidazole-4-carboxamide, 5-amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• NSC 105823
• 5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide
• 1H-Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-

5-Aminoimidazole-4-carboxamide 1-β-D-Ribofuranoside

CAS: 2627-69-2

Fórmula: C₉H₁₄N₄O₅

Pureza: >98.0%(HPLC)

Cor e Forma: White to Light yellow to Light red powder to crystal

Peso molecular: 258.23

Ref: 3B-A2528

5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside, 98%

CAS: 2627-69-2

Activator of AMP-activated protein kinase (AMPK)

Fórmula: C₉H₁₄N₄O₅

Pureza: 98%

Peso molecular: 258.23

Ref: 02-J64720

AICAR

CAS: 2627-69-2

AICAR (Acadesine) is an AMPK activator, metabolic regulation, muscle function regulation, anti-cancer effect, neuroprotection. High-Quality, Low-Cost!

Fórmula: C₉H₁₄N₄O₅

Pureza: 98.00% - ≥95%

Cor e Forma: Solid

Peso molecular: 258.23

Ref: TM-T1477

AICAR

CAS: 2627-69-2

AICAR

Pureza: ≥95%

Peso molecular: 258.23g/mol

Ref: 54-BUP11706

5-Amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxamide

CAS: 2627-69-2

5-Amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxamide

Fórmula: C₉H₁₄N₄O₅

Pureza: 97%

Cor e Forma: off-white to white solid

Peso molecular: 258.23g/mol

Ref: 54-OR1170T

Acadesine

CAS: 2627-69-2

Fórmula: C₉H₁₄N₄O₅

Pureza: ≥ 98.0%

Cor e Forma: White to beige solid

Peso molecular: 258.23

Ref: 7W-GP6637

5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside

CAS: 2627-69-2

Applications AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)

Fórmula: C₉H₁₄N₄O₅

Cor e Forma: Neat

Peso molecular: 258.23

Ref: TR-A611700

5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose

CAS: 2627-69-2

Acadesine is a purine nucleoside analogue that inhibits the synthesis of ATP in cells. Acadesine blocks phosphorylation of adenosine monophosphate (AMP) to adenosine triphosphate (ATP) by inhibiting the activity of kinase-3, an enzyme involved in the production of ATP. Acadesine also inhibits the release of ATP from muscle cells into the blood stream and preferentially targets kidney cells, thereby reducing renal injury. Acadesine has been shown to be effective at reducing proteinuria and improving renal function in rats with acute kidney injury. Acadesine also has anti-inflammatory properties due to its ability to inhibit proteins that are involved in inflammation.

Fórmula: C₉H₁₄N₄O₅

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 258.23 g/mol

Ref: 3D-NA03552

AICA Riboside

CAS: 2627-69-2

M04018 - AICA Riboside

Fórmula: C₉H₁₄N₄O₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 258.234

Ref: 10-M04018

5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-15N4

Produto Controlado

CAS: 2627-69-2

Applications A labelled nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)

Fórmula: C₉H₁₄₁₅N₄O₅

Cor e Forma: Neat

Peso molecular: 262.20

Ref: TR-A611703

5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide

CAS: 2627-69-2

Fórmula: C₉H₁₄N₄O₅

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 258.2313

Ref: IN-DA0034FR