CAS 2657-25-2

4'-Hidroxicalcona

Descrição:

4'-Hidroxicalcona é um composto orgânico pertencente à família dos chalconas, caracterizado por sua estrutura que apresenta uma espinha dorsal de chalcona com um grupo hidroxila na posição para do anel fenílico. Normalmente aparece como um sólido cristalino amarelo a laranja e é conhecido por suas potenciais atividades biológicas, incluindo propriedades antioxidantes, anti-inflamatórias e antimicrobianas. O composto é solúvel em solventes orgânicos como etanol e metanol, mas tem solubilidade limitada em água. Sua fórmula molecular é C15H12O2 e possui um peso molecular relativamente baixo. 4'-Hidroxicalcona é frequentemente estudado por seu papel em várias vias bioquímicas e suas potenciais aplicações em farmacêuticos e nutracêuticos. Além disso, serve como precursor na síntese de outros flavonoides e compostos bioativos. A reatividade do composto pode ser atribuída à presença do grupo hidroxila, que pode participar de ligações de hidrogênio e influenciar sua interação com alvos biológicos.

Fórmula: C₁₅H₁₂O₂

InChI: InChI=1/C15H12O2/c16-14-9-7-13(8-10-14)15(17)11-6-12-4-2-1-3-5-12/h1-11,16H/b11-6+

Chave InChI: InChIKey=UAHGNXFYLAJDIN-UHFFFAOYSA-N

SMILES: C(C=CC1=CC=CC=C1)(=O)C2=CC=C(O)C=C2

Sinónimos:

• (2E)-1-(4-hydroxyphenyl)-3-phenylprop-2-en-1-one
• 1-(4-Hydroxyphenyl)-3-Phenylprop-2-En-1-One
• 1-(4-Hydroxyphenyl)-3-phenyl-2-propen-1-one
• 1-(4-Hydroxyphenyl)-3-phenylpropenone
• 2-Propen-1-one, 1-(4-hydroxyphenyl)-3-phenyl-
• 4-Hydroxyphenyl styryl ketone
• Benzylidene-(4-hydroxyacetophenone)
• Chalcone, 4′-hydroxy-
• NSC 242264
• p-Cinnamoylphenol
• 4′-Hydroxychalcone
• HYDROXYCHALCONE, 4'-
• 4'-Hydroxychalcone98%
• 2-BENZAL-4'-HYDROXYACETOPHENONE
• 1-(p-Hydroxyphenyl)-3-phenyl-2-propene-1-one
• 2-BENZYLIDENE-4'-HYDROXYACETOPHENONE
• HYDROXYCHALCONE, 4-(RG)
• 4'-Hydroxychalcone,97%

4'-Hydroxychalcone

CAS: 2657-25-2

Fórmula: C₁₅H₁₂O₂

Pureza: >95.0%(GC)

Cor e Forma: Light orange to Yellow to Green powder to crystal

Peso molecular: 224.26

Ref: 3B-H0945

4'-Hydroxychalcone, 97%

CAS: 2657-25-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₅H₁₂O₂

Pureza: 97%

Cor e Forma: Crystals or powder or crystalline powder, White to pale yellow

Peso molecular: 224.26

Ref: 02-A10838

2-Propen-1-one, 1-(4-hydroxyphenyl)-3-phenyl-

CAS: 2657-25-2

Fórmula: C₁₅H₁₂O₂

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 224.2546

Ref: IN-DA002TQO

4'-Hydroxychalcone

CAS: 2657-25-2

4'-Hydroxychalcone

Pureza: ≥98%

Peso molecular: 224.25g/mol

Ref: 54-BUP16799

4'-Hydroxychalcone

CAS: 2657-25-2

4'-Hydroxychalcone

Fórmula: C₁₅H₁₂O₂

Pureza: 98%

Cor e Forma: Pale Yellow Powder

Peso molecular: 224.25g/mol

Ref: 54-OR2345

4'-Hydroxychalcone

CAS: 2657-25-2

4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity

Fórmula: C₁₅H₁₂O₂

Pureza: 99.86% - 99.87%

Cor e Forma: Yellow-Cream Powder

Peso molecular: 224.25

Ref: TM-T7917

4'-Hydroxychalcone

CAS: 2657-25-2

4'-Hydroxychalcone is a compound that has shown to be an insulin resistance suppressant. It reduces the activity of recombinant cytochrome P450 enzymes and blocks hydroxy group metabolism, which leads to a decrease in ATP levels. This molecule also has biological properties as it can inhibit the expression of β-catenin and induce apoptosis in cancer cells. 4'-Hydroxychalcone has been found to inhibit the transfer mechanism of phosphatidylinositol 3-kinase (PTP1B) and is able to bind with the protein marker p62/SQSTM1.
4'-Hydroxychalcone is a potent inhibitor for PTP1B, which is a negative regulator for insulin signaling pathways. In addition, 4'-hydroxychalcone can bind with p62/SQSTM1, which is a marker for autophagy proteins. These properties have been shown to have anti-cancer effects on multiple cancer types including

Fórmula: C₁₅H₁₂O₂

Cor e Forma: Powder

Peso molecular: 224.25 g/mol

Ref: 3D-FH36595

4′-Hydroxychalcone

CAS: 2657-25-2

Fórmula: C₁₅H₁₂O₂

Pureza: 97%

Cor e Forma: Solid, Yellow-cream powder

Peso molecular: 224.259

Ref: 10-F003112