CAS: 267243-28-7 - Canertinib

Fórmula: C₂₃H₂₃ClFN₅O₃

InChI: InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)

Chave InChI: InChIKey=OMZCMEYTWSXEPZ-UHFFFAOYSA-N

SMILES: O=C(C=C)NC1=CC=2C(=NC=NC2NC3=CC=C(F)C(Cl)=C3)C=C1OCCCN4CCOCC4

Sinónimos:

• 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-
• 4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propyloxy]-6-[(vinylcarbonyl)amino]quinazoline
• Canertinib base
• Cl 1033
• N-[4-(3-Chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]acrylamide
• N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide
• N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[2-(morpholin-4-yl)ethoxy]quinazolin-6-yl}prop-2-enamide
• N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide

Canertinib

CAS: 267243-28-7

• Fórmula: C₂₄H₂₅ClFN₅O₃
• Pureza: 97%
• Cor e Forma: Solid
• Peso molecular: 485.9384

Canertinib

CAS: 267243-28-7

Canertinib

CAS: 267243-28-7

Canertinib (CI-1033) is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma …

• Fórmula: C₂₄H₂₅ClFN₅O₃
• Pureza: 100%
• Cor e Forma: White Or Similar To White Crystalline Powder
• Peso molecular: 485.94

Canertinib (CI-1033)

CAS: 267243-28-7

Canertinib is a small molecule that inhibits the protein synthesis of cancer cells by inhibiting …

• Fórmula: C₂₄H₂₅ClFN₅O₃
• Pureza: Min. 95%
• Peso molecular: 485.94 g/mol

Canertinib

CAS: 267243-28-7

Applications Antineoplastic; irreversible pan-erbB tyrosine kinase inhibitor used to treat cancer. References Li, D., et …

• Fórmula: C₂₄H₂₅ClFN₅O₃
• Cor e Forma: Pale Yellow Solid
• Peso molecular: 485.94