CAS 27244-64-0

6-Hidroxi-L-DOPA

Descrição:

6-Hidroxi-L-DOPA, com o número CAS 27244-64-0, é um composto químico que é um derivado da L-DOPA, um precursor de aminoácidos da dopamina. Este composto apresenta um grupo hidroxila na posição 6 do anel aromático, o que o distingue de seu composto pai. É tipicamente caracterizado por seu papel em vias bioquímicas, particularmente na síntese de neurotransmissores. 6-Hidroxi-L-DOPA é de interesse em neurofarmacologia e pesquisa relacionada à doença de Parkinson, pois pode influenciar a atividade dopaminérgica. O composto é geralmente solúvel em água e exibe propriedades típicas de compostos fenólicos, como potencial atividade antioxidante. Sua estabilidade e reatividade podem ser influenciadas por fatores ambientais, como pH e temperatura. Assim como muitas substâncias bioquímicas, é importante manusear 6-Hidroxi-L-DOPA com cuidado em ambientes de laboratório, aderindo a protocolos de segurança para mitigar quaisquer riscos potenciais associados ao seu uso.

Fórmula: C₉H₁₁NO₅

InChI: InChI=1S/C9H11NO5/c10-5(9(14)15)1-4-2-7(12)8(13)3-6(4)11/h2-3,5,11-13H,1,10H2,(H,14,15)/t5-/m0/s1

Chave InChI: InChIKey=YLKRUSPZOTYMAT-YFKPBYRVSA-N

SMILES: C([C@@H](C(O)=O)N)C1=C(O)C=C(O)C(O)=C1

Sinónimos:

• (2S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid
• 2,4,5-Trihydroxy-<span class="text-smallcaps">L</span>-phenylalanine
• 2,4,5-Trihydroxy-L-phenylalanine
• 2,4,5-Trihydroxyphenylalanine
• 2,5-Dihydroxy-<span class="text-smallcaps">L</span>-tyrosine
• 2,5-Dihydroxy-L-tyrosine
• 3-(3,4,6-Trihydroxyphenyl)-<span class="text-smallcaps">L</span>-alanine
• 3-(3,4,6-Trihydroxyphenyl)-L-alanine
• 6-Hydroxy-<span class="text-smallcaps">L</span>-DOPA
• 6-Hydroxy-L-DOPA
• <span class="text-smallcaps">L</span>-6-Hydroxydopa
• <span class="text-smallcaps">L</span>-Tyrosine, 2,5-dihydroxy-
• Alanine, 3-(2,4,5-trihydroxyphenyl)-, <span class="text-smallcaps">L</span>-
• Alanine,3-(2,4,5-trihydroxyphenyl)-, L- (8CI)
• Hydroxy-<span class="text-smallcaps">L</span>-dopa
• Hydroxy-L-dopa
• L-6-Hydroxydopa
• Topa
• L-Tyrosine, 2,5-dihydroxy-

Levodopa EP Impurity A

CAS: 27244-64-0

Fórmula: C₉H₁₁NO₅

Peso molecular: 213.19

Ref: ST-EA-CP-L16001

Levodopa Related Compound A (3-(2,4,5-Trihydroxyphenyl)-L-alanine)

CAS: 27244-64-0

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Fórmula: C₉H₁₁NO₅

Cor e Forma: Brown Grey Powder

Peso molecular: 213.06372

Ref: 45-1361010

2,5-Dihydroxy-L-tyrosine

CAS: 27244-64-0

Fórmula: C₉H₁₁NO₅

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 213.1873

Ref: IN-DA00C28S

(S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid

CAS: 27244-64-0

(S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid

Pureza: 97%

Peso molecular: 213.19g/mol

Ref: 54-OR1074264

Levodopa EP Impurity A (Levodopa USP Related Compound A, 6-Hydroxy L-DOPA)

CAS: 27244-64-0

Fórmula: C₉H₁₁NO₅

Peso molecular: 213.19

Ref: 4Z-D-3229

6-Hydroxy-L-DOPA

Produto Controlado

CAS: 27244-64-0

Impurity Levodopa EP Impurity A; Levodopa USP Related Compound A
Stability Hygroscopic
Applications 6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.
References Jaim-Etcheverry, G. et al.: Brain Res., 100, 699 (1975); Kostrzewa, R.M. et al.: Amino Acids, 14, 175 (1998); Berthet, A. et al.: J. Neurosci., 29, 4829 (2009);

Fórmula: C₉H₁₁NO₅

Cor e Forma: Brown To Black

Peso molecular: 213.19

Ref: TR-H941725

6-Hydroxy-L-DOPA

CAS: 27244-64-0

6-Hydroxy-L-DOPA is a quinone, which is the cofactor of tetracycline resistance. It is also a component of tricyclic antidepressant drugs, and has been shown to have neuroprotective effects. 6-Hydroxy-L-DOPA binds to the polymerase chain reaction (PCR) by way of a signal peptide sequence and can be used as a pharmacological agent in patients with oxidative injury. 6-Hydoxy-L-DOPA is bound in the form of an oxidized quinone ring, which coordinates with copper ions via two oxygen atoms and two nitrogen atoms. The structure has been determined using x-ray crystal structures. This compound has an oxidase activity that generates hydrogen peroxide from hydrogen peroxide and water, which results in oxidative injury.

Fórmula: C₉H₁₁NO₅

Pureza: Min. 95%

Peso molecular: 213.19 g/mol

Ref: 3D-FH24378

6-Hydroxy-L-DOPA

CAS: 27244-64-0

Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent and catecholamine-selective neurot

Fórmula: C₉H₁₁NO₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 213.19

Ref: TM-T20396