CAS: 273404-37-8 - N-(4-Amino-3-chlorobenzoyl)-3-methyl-L-valyl-N-[(2R,3S)-2-ethoxytetrahydro-5-oxo-3-furanyl]-L-prolinamide

Fórmula: C₂₄H₃₃ClN₄O₆

InChI: InChI=1S/C24H33ClN4O6/c1-5-34-23-16(12-18(30)35-23)27-21(32)17-7-6-10-29(17)22(33)19(24(2,3)4)28-20(31)13-8-9-15(26)14(25)11-13/h8-9,11,16-17,19,23H,5-7,10,12,26H2,1-4H3,(H,27,32)(H,28,31)/t16-,17-,19+,23+/m0/s1

Chave InChI: InChIKey=SJDDOCKBXFJEJB-MOKWFATOSA-N

SMILES: O=C1OC(OCC)C(NC(=O)C2N(C(=O)C(NC(=O)C3=CC=C(N)C(Cl)=C3)C(C)(C)C)CCC2)C1

Sinónimos:

• <span class="text-smallcaps">L</smallcap>-Prolinamide, N-(4-amino-3-chlorobenzoyl)-3-methyl-<smallcap>L</span>-valyl-N-[(2R,3S)-2-ethoxytetrahydro-5-oxo-3-furanyl]-
• Belnacasan
• N-(4-Amino-3-chlorobenzoyl)-3-methyl-<span class="text-smallcaps">L</smallcap>-valyl-N-[(2R,3S)-2-ethoxytetrahydro-5-oxo-3-furanyl]-<smallcap>L</span>-prolinamide
• Vx 765
• Vx765

N-(4-Amino-3-chlorobenzoyl)-3-methyl-L-valyl-N-[(2R,3S)-2-ethoxytetrahydro-5-oxo-3-furanyl]-L-prolinamide

CAS: 273404-37-8

• Fórmula: C₂₄H₃₃ClN₄O₆
• Pureza: 98%
• Cor e Forma: Solid
• Peso molecular: 508.9950

VX-765

CAS: 273404-37-8

• Fórmula: C₂₄H₃₃ClN₄O₆
• Pureza: >95.0%(HPLC)
• Cor e Forma: White to Light yellow powder to crystal
• Peso molecular: 509.00

Belnacasan

CAS: 273404-37-8

Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.

• Fórmula: C₂₄H₃₃ClN₄O₆
• Pureza: 96.53% - 99.5%
• Cor e Forma: Solid
• Peso molecular: 508.99

VX-765

CAS: 273404-37-8

Applications VX-765 shows anti-convulsant activity by inhibiting interlukin-1β biosynthesis. References Maroso, M. et al.: Neurother., …

• Fórmula: C₂₄H₃₃ClN₄O₆
• Cor e Forma: Neat
• Peso molecular: 509.00

VX 765

CAS: 273404-37-8

A prodrug of VRT 043198 that inhibits IL-converting enzyme (ICE)/caspase-1. Inhibits LPS-induced secretion of cytokines. …

• Fórmula: C₂₄H₃₃ClN₄O₆
• Pureza: Min. 95%
• Cor e Forma: White Powder
• Peso molecular: 508.99 g/mol