CAS 27409-30-9

Picroside I

Descrição:

Picroside I é um composto glicósido derivado principalmente das raízes da planta Picrorhiza kurroa, conhecida por suas propriedades medicinais na medicina tradicional. É caracterizado por seu sabor amargo e frequentemente estudado por seus potenciais efeitos farmacológicos, incluindo atividades hepatoprotetoras, anti-inflamatórias e antioxidantes. A estrutura química de Picroside I consiste em um moiety de glicose ligado a uma aglicona fenólica, contribuindo para sua atividade biológica. É solúvel em água e solventes orgânicos, tornando-o versátil para várias aplicações em formulações herbais e pesquisa. Além disso, Picroside I tem sido investigado por seu papel na melhoria da função hepática e seu uso potencial no tratamento de distúrbios hepáticos. Seu perfil de segurança e eficácia são temas de pesquisa em andamento, enfatizando a importância de entender seus mecanismos de ação e potencial terapêutico. No geral, Picroside I representa um composto significativo no campo dos produtos naturais e farmacognosia.

Fórmula: C₂₄H₂₈O₁₁

InChI: InChI=1S/C24H28O11/c25-11-24-16-13(17(27)21(24)35-24)8-9-31-22(16)34-23-20(30)19(29)18(28)14(33-23)10-32-15(26)7-6-12-4-2-1-3-5-12/h1-9,13-14,16-23,25,27-30H,10-11H2/b7-6+/t13-,14-,16-,17+,18-,19+,20-,21+,22+,23+,24-/m1/s1

Chave InChI: InChIKey=XZGPUOQGERGURE-LUVHZPKESA-N

SMILES: C(O)[C@@]12[C@@](O1)([C@@H](O)[C@]3([C@@]2([C@H](O[C@@H]4O[C@H](COC(/C=C/C5=CC=CC=C5)=O)[C@@H](O)[C@H](O)[C@H]4O)OC=C3)[H])[H])[H]

Sinónimos:

• (1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-2-yl 6-O-[(2E)-3-phenylprop-2-enoyl]-beta-D-glucopyranoside
• 6'-Cinnamoylcatalpol
• Amphicoside I
• Picroside I
• beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, 6-(3-phenyl-2-propenoate), (1aS-(1aalpha,1bbeta,2beta(E),5abeta,6beta,6aalpha))-
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-[(2E)-3-phenyl-2-propenoate]
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-(3-phenyl-2-propenoate), [1aS-[1aα,1bβ,2β(E),5aβ,6β,6aα]]-
• β-d-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-(3-phenyl-2-propenoate), [1aS-[1aα,1bβ,2β(E),5aβ,6β,6aα]]-
• β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-[(2E)-3-phenyl-2-propenoate]

Picroside I

CAS: 27409-30-9

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Fórmula: C₂₄H₂₈O₁₁

Cor e Forma: White Powder

Peso molecular: 492.16316

Ref: 45-1538312

Picroside I

CAS: 27409-30-9

Fórmula: C₂₄H₂₈O₁₁

Pureza: 98%

Peso molecular: 492.4725

Ref: IN-DA00BBRS

Picroside I

CAS: 27409-30-9

Picroside I

Pureza: ≥98%

Peso molecular: 492.47g/mol

Ref: 54-BUP00055

Picroside I

CAS: 27409-30-9

Picroside I

Pureza: 98%

Peso molecular: 492.47g/mol

Ref: 54-OR1023026

Picroside 1

CAS: 27409-30-9

Fórmula: C₂₄H₂₈O₁₁

Peso molecular: 492.47

Ref: 7W-GC1565

Picroside I

CAS: 27409-30-9

Fórmula: C₂₄H₂₈O₁₁

Pureza: >95.0%(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 492.48

Ref: 3B-P2593

Picroside I

CAS: 27409-30-9

Picroside I is a hepatoprotective agent which is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable anti-invasive drug candidates for cancer therapy by suppressing Collagenases and Gelatinases. Picroside I can enhance basic fibroblast growth factor(bFGF)-, staurosporine- or dbc-mitogen-activated protein (MAP)-induced neurite outgrowth from PC12D cells.

Fórmula: C₂₄H₂₈O₁₁

Pureza: 95%~99%

Peso molecular: 492.477

Ref: BP-BP1099

Picroside I

CAS: 27409-30-9

Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B.

Fórmula: C₂₄H₂₈O₁₁

Pureza: 99.70%

Cor e Forma: Solid

Peso molecular: 492.47

Ref: TM-T2787

Picroside i

CAS: 27409-30-9

Natural glycoside

Fórmula: C₂₄H₂₈O₁₁

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 492.48

Ref: 5G-89758

Picroside I

CAS: 27409-30-9

Picroside I is a naturally occurring iridoid glycoside, which is extracted from the plant Picrorhiza kurroa, commonly found in the Himalayan region. This compound acts primarily through its hepatoprotective and antioxidant properties, intervening in cellular pathways to reduce oxidative stress and inhibit inflammatory mediators. It effectively modulates liver enzymes and stabilizes cell membranes, thus supporting liver health.

Fórmula: C₂₄H₂₈O₁₁

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 492.48 g/mol

Ref: 3D-MP10467