CAS 27469-60-9

1-Bis(4-fluorofenil)metil piperazina

Descrição:

1-Bis(4-fluorofenil)metil piperazina, com o número CAS 27469-60-9, é um composto químico caracterizado por seu núcleo de piperazina, que é uma amina heterocíclica de seis membros. Este composto apresenta dois grupos para-fluorofenila ligados a um anel central de piperazina, contribuindo para suas propriedades únicas. Normalmente é um sólido à temperatura ambiente e exibe solubilidade moderada em solventes orgânicos, que é influenciada pela presença dos átomos de flúor que aumentam sua lipofilicidade. Os substituintes de flúor também podem afetar as propriedades eletrônicas do composto, potencialmente influenciando sua reatividade e interação com alvos biológicos. 1-Bis(4-fluorofenil)metil piperazina pode ser de interesse na química medicinal, particularmente no desenvolvimento de fármacos, devido às suas características estruturais que podem modular a atividade biológica. Além disso, sua síntese e caracterização envolvem técnicas padrão de química orgânica, e pode ser estudado por suas potenciais aplicações em vários campos, incluindo design de fármacos e ciência dos materiais.

Fórmula: C₁₇H₁₈F₂N₂

InChI: InChI=1/C17H18F2N2/c18-15-5-1-13(2-6-15)17(21-11-9-20-10-12-21)14-3-7-16(19)8-4-14/h1-8,17,20H,9-12H2/p+2

Chave InChI: InChIKey=TTXIFFYPVGWLSE-UHFFFAOYSA-N

SMILES: C(C1=CC=C(F)C=C1)(C2=CC=C(F)C=C2)N3CCNCC3

Sinónimos:

• 1-(4,4'-Difluorobenzhydryl)Piperazine
• 1-(Di-p-fluorobenzhydryl)piperazine
• 1-[Bis(4-Fluorophenyl)Methyl]Piperazinediium
• 4,4'-Difluorobenzhydrylpiperazine
• 4-[Bis(4-fluorophenyl)methyl]piperazine
• Di(4-fluorophenyl)methyl piperazine
• N-(4,4-Difluorobenzhydryl)piperazine
• N-(Bis(4-fluorophenyl)methyl)piperazine
• Piperazine, 1-[bis(4-fluorophenyl)methyl]-
• Piperazine, 1-[bis(p-fluorophenyl)methyl]-
• R 19352
• T 841
• 1-[Bis(4-fluorophenyl)methyl]piperazine
• 1-[Bis(4-fluorophenyl)methyl]piperazine
• 1-(bis(4-fluorophenyl)methyl) piperazine
• 1-(4,4'-Diflurobenzhydryl)piperazine
• 1-(4,4'-DIFLUORODIPHENYLMETHYL)PIPERAZINE
• 1-(4,4'-Difluorobenzhydryl)piperazine 97%
• 1-[BIS(4-FLUOROPHENYL)METHYL]PIPERAZINE HYDROGEN CHLORIDE
• N-(4,4"-DIFLUOROBENZYLHYDRYL) PIPERAZINE
• 1-BIS (P-FLUOROPHENYL) METHYL PIPERAZINE
• 4,4-Difluorobenzhydrolpiperazine
• 1-[BIS(4-FLUOROPHENZYL)METHYL]PIPERAZINE
• 1-BIS(4-FLUOROPHENYL)METHYL PIPERAZINE 97%
• 1-(4,4'-Difluorobenzhydryl)piperazine97%
• TIMTEC-BB SBB002996
• 1-[DI(4-FLUOROPHENYL)METHYL]PIPERAZINE
• 1-[Bis(4-Fluorophenyl)methyl]p
• 4,4'-DIFLUOROBENZHYDRYL PIPERAZINE

1-[Bis(4-fluorophenyl)methyl]piperazine

CAS: 27469-60-9

Fórmula: C₁₇H₁₈F₂N₂

Pureza: >97.0%(GC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 288.34

Ref: 3B-B2764

1-Bis(4-fluorophenyl)methyl piperazine

CAS: 27469-60-9

Fórmula: C₁₇H₁₈F₂N₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 288.3350

Ref: IN-DA003KF5

Flunarizine EP Impurity A

CAS: 27469-60-9

Fórmula: C₁₇H₁₈F₂N₂

Cor e Forma: White To Off-White Solid

Peso molecular: 288.34

Ref: 4Z-F-084009

1-[Bis(4-fluorophenyl)methyl]piperazine

CAS: 27469-60-9

1-[Bis(4-fluorophenyl)methyl]piperazine

Fórmula: C₁₇H₁₈F₂N₂

Pureza: 98%

Cor e Forma: white to off-white powder

Peso molecular: 288.34g/mol

Ref: 54-PC5636

Flunarizine EP Impurity A

Produto Controlado

CAS: 27469-60-9

Fórmula: C₁₇H₁₈F₂N₂

Cor e Forma: Neat

Peso molecular: 288.34

Ref: 86-MM0175.04

1-Bis(4-fluorophenyl)methyl Piperazine

Produto Controlado

CAS: 27469-60-9

Impurity Flumazenil EP Impurity A
Stability Hygroscopic
Applications 1-Bis(4-fluorophenyl)methyl Piperazine (Flumazenil EP Impurity A) is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives. Impurity of F455200
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yin, Y. et al.: Bioorg. Med. Chem., 22, 2409 (2014); Gurdal, E. et al.: J. Enz. Inhib. Med. Chem., 29, 205 (2014);

Fórmula: C₁₇H₁₈F₂N₂

Cor e Forma: White To Light Yellow

Peso molecular: 288.34

Ref: TR-B434875

1-[Bis-(4-fluorophenyl)methyl]piperazine

CAS: 27469-60-9

Fórmula: C₁₇H₁₈F₂N₂

Pureza: 97.0%

Cor e Forma: Solid

Peso molecular: 288.342

Ref: 10-F019234

1-Bis(4-fluorophenyl)methyl Piperazine-d8

Produto Controlado

CAS: 27469-60-9

Applications 1-Bis(4-fluorophenyl)methyl Piperzaine-d8 is a labelled analogue of 1-Bis(4-fluorophenyl)methyl Piperzaine (B434875), which is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives. Impurity of F455200. It is also an intermediate in synthesizing Flunarizine-d8 Dihydrochloride (F455202), which is a calcium channel blocker; fluorinated derivative of Cinnarizine. Vasodilator (cerebral and peripheral).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yin, Y. et al.: Bioorg. Med. Chem., 22, 2409 (2014); Gurdal, E. et al.: J. Enz. Inhib. Med. Chem., 29, 205 (2014); Desmedt, L.K., et al.: Arzneim.-Forsch., 25, 1408 (1975); Godfraind, T., et al.: Eur. J. Pharmacol., 53, 273 (1979); Nihard, P., et al.: Angiology, 33, 37 (1982); Holmes, B., et al.: Drugs, 27, 6 (1984);

Fórmula: C₁₇H₁₀D₈F₂N₂

Cor e Forma: Neat

Peso molecular: 296.38

Ref: TR-B434877

Flunarizine EP Impurity A

CAS: 27469-60-9

Fórmula: C₁₇H₁₈F₂N₂

Peso molecular: 288.34

Ref: ST-EA-CP-F140003

1-(4,4'-Difluorobenzhydry)piperazine

CAS: 27469-60-9

1-(4,4'-Difluorobenzhydry)piperazine (1-DFBP) is a potential antitumor agent that has been shown to inhibit the growth of leukemia cells. It may be an inhibitor of apoptotic cell death, as it has been shown to induce hydrogen bond formation with coumarin derivatives. 1-DFBP has also been shown to have inhibitory activities against leukemia HL-60 cells, and is a competitive inhibitor of cinnarizine. The catalytic mechanism for 1-DFBP is not known, although kinetic data suggest that it involves hydrogen bonding and/or pi stacking interactions.

Fórmula: C₁₇H₁₈F₂N₂

Pureza: Min. 95%

Peso molecular: 288.34 g/mol

Ref: 3D-FD55069