CAS 2760515-88-4

mG2N001

CAS: 2760515-88-4

mG2N001, a negative allosteric modulator (NAM) of the metabotropic glutamate receptor mGluR2, has an IC50 of 93 nM and binds to mGluR2 as an antagonist with a Ki of 63 nM. This compound is microparticle- and plasma-stable, and its radioisotope [11C] mG2N001 can be utilized in PET imaging. [11C] mG2N001 exhibits good brain heterogeneity and penetration, selectively accumulating in mGluR2-rich regions to produce high-contrast brain images [1].

Fórmula: C₁₈H₁₉FN₂O₃

Cor e Forma: Solid

Peso molecular: 330.35

Ref: TM-T86893