CAS 2848-96-6

Acetato de lorazepam

Descrição:

Acetato de lorazepam, com o número CAS 2848-96-6, é um derivado do lorazepam, um medicamento que pertence à classe das benzodiazepinas. É caracterizado principalmente por suas propriedades sedativas, ansiolíticas e anticonvulsivantes, tornando-o útil no tratamento de transtornos de ansiedade, insônia e manejo de convulsões. O composto exibe uma alta afinidade pelo receptor GABA-A, aumentando os efeitos inibitórios do neurotransmissor ácido gama-aminobutírico (GABA) no sistema nervoso central. Acetato de lorazepam é tipicamente administrado em sua forma de acetato para melhorar a solubilidade e a biodisponibilidade. É um pó cristalino branco a off-white, relativamente estável em condições normais, e é solúvel em solventes orgânicos como etanol e dimetilsulfóxido (DMSO). A farmacocinética de Acetato de lorazepam envolve rápida absorção e distribuição, com uma meia-vida moderada, permitindo um manejo eficaz de episódios agudos de ansiedade. Assim como outras benzodiazepinas, recomenda-se cautela devido ao potencial de dependência e sintomas de abstinência com o uso prolongado.

Fórmula: C₁₇H₁₂Cl₂N₂O₃

InChI: InChI=1/C17H12Cl2N2O3/c1-9(22)24-17-16(23)20-14-7-6-10(18)8-12(14)15(21-17)11-4-2-3-5-13(11)19/h2-8,17H,1H3,(H,20,23)

Chave InChI: InChIKey=CYDZMDOLVUBPNL-UHFFFAOYSA-N

SMILES: ClC1=C(C=2C=3C(NC(=O)C(OC(C)=O)N2)=CC=C(Cl)C3)C=CC=C1

Sinónimos:

• 2H-1,4-Benzodiazepin-2-one, 3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-
• 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-, acetate
• 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-, acetate (ester)
• 3-(Acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
• 3-Acetoxy-7-chloro-5-(o-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
• 7-chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl acetate
• Lorazepam acetate
• Ro 7-8407
• 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-2-oxo-2H-1,4-benzodiazepin-3-yl acetate
• [7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] ethanoate
• Acetic acid [7-chloro-5-(2-chlorophenyl)-2,3-dihydro-2-oxo-1H-1,4-benzodiazepin]-3-yl ester
• acetic acid [7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] ester
• CYDZMDOLVUBPNL-UHFFFAOYSA-N
• Lorazepam USP Related Compound A
• Lorazepam 3-acetate
• Lorazepam Related Compound A (25 mg) (7-Chloro-5-(ochlorophenyl)-1,3-dihydro-3-acetoxy-2H-1,4-benzodiazepin-2-one)
• Lorazepam Related Compound A (7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-acetoxy-2H-1,4-benzodiazepi (1370327)
• LorazepaM Related CoMpound A
• [7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] acetate

Lorazepam Acetate ((3RS)-7-Chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl Acetate)

Produto Controlado

CAS: 2848-96-6

Cor e Forma: Neat

Ref: 61-FOR0071.07

Lorazepam Acetate ((3RS)-7-Chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl Acetate) 0.1 mg/ml in Acetonitrile

Produto Controlado

CAS: 2848-96-6

Cor e Forma: Single Solution

Ref: 61-AMP0071.07-12

Lorazepam Related Compound A (7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-acetoxy-2H-1,4-benzodiazepin-2-one)

CAS: 2848-96-6

Drugs with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

Fórmula: C₁₇H₁₂Cl₂N₂O₃

Cor e Forma: Off-White Powder

Peso molecular: 362.0225

Ref: 45-1370327

(3RS)-7-Chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-ylAcetate (Lorazepam Acetate)

Produto Controlado

CAS: 2848-96-6

Cor e Forma: Neat

Ref: 86-MM0071.07

Lorazepam EP Impurity B

CAS: 2848-96-6

Fórmula: C₁₇H₁₂Cl₂N₂O₃

Peso molecular: 363.19

Ref: ST-EA-CP-L85015

Lorazepam Acetate

Produto Controlado

CAS: 2848-96-6

Fórmula: C₁₇H₁₂Cl₂N₂O₃

Cor e Forma: Neat

Peso molecular: 363.19

Ref: TR-L469840

3-(Acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Produto Controlado

CAS: 2848-96-6

3-(Acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one is a drug that binds to human serum albumin. It is an enantiomer of lorazepam and is a specific ligand for α1 acid glycoprotein. This compound has been shown to be effective in the treatment of epilepsy and benzodiazepine withdrawal syndrome. It also has a cavity that can be used to bind reactive molecules such as carbamazepine. 3-(Acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin--2--one has been shown to have antitumour effects on cultured cells by inhibiting protein synthesis, thus leading to cell death.

Fórmula: C₁₇H₁₂Cl₂N₂O₃

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 363.19 g/mol

Ref: 3D-FA151720

2H-1,4-Benzodiazepin-2-one, 3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-

CAS: 2848-96-6

Fórmula: C₁₇H₁₂Cl₂N₂O₃

Peso molecular: 363.1948

Ref: IN-DA002VHM