CAS 28860-95-9: Carbidopa

Descrição: Carbidopa é um composto farmacêutico utilizado principalmente no tratamento da doença de Parkinson e seus sintomas. Funciona como um inibidor da dopa descarboxilase, que impede a conversão de levodopa em dopamina nos tecidos periféricos, aumentando assim a disponibilidade de levodopa para o cérebro, onde pode ser convertida em dopamina. Esse mecanismo melhora os efeitos terapêuticos da levodopa enquanto minimiza efeitos colaterais como náuseas e vômitos. Carbidopa é frequentemente administrado em combinação com levodopa para melhorar a eficácia do tratamento. O composto é caracterizado por sua fórmula molecular, que inclui átomos de carbono, hidrogênio, nitrogênio e oxigênio. Geralmente é administrado por via oral e é bem absorvido no trato gastrointestinal. Carbidopa tem um perfil de toxicidade relativamente baixo, mas pode causar efeitos colaterais como tontura, boca seca ou discinesia em alguns pacientes. Sua farmacocinética envolve rápida absorção e uma meia-vida relativamente curta, necessitando de múltiplas doses ao longo do dia para um efeito terapêutico ideal.

Fórmula: C₁₀H₁₄N₂O₄

InChI: InChI=1S/C10H14N2O4/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6/h2-4,12-14H,5,11H2,1H3,(H,15,16)/t10-/m0/s1

Chave InChI: InChIKey=TZFNLOMSOLWIDK-JTQLQIEISA-N

SMILES: O=C(O)C(NN)(C)CC1=CC=C(O)C(O)=C1

Sinónimos:

• (-)-<span class="text-smallcaps">L</span>-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinamic acid
• (-)-<span class="text-smallcaps">L</span>-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid monohydrate
• (-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinamic acid
• (-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid monohydrate
• (2S)-2-(Aminoazaniumyl)-3-(3,4-dihydroxyphenyl)-2-methylpropanoate
• (2S)-3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
• (S)-Carbidopa
• (αS)-α-Hydrazinyl-3,4-dihydroxy-α-methylbenzenepropanoic acid
• 1-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic acid
• <span class="text-smallcaps">L</span>-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
• <span class="text-smallcaps">L</span>-Carbidopa
• <span class="text-smallcaps">L</span>-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic acid
• <span class="text-smallcaps">L</span>-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid
• <span class="text-smallcaps">L</span>-α-Hydrazino-α-methyl-3,4-dihydroxyphenylpropionic acid
• <span class="text-smallcaps">L</span>-α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic acid
• <span class="text-smallcaps">L</span>-α-Methyl-α-hydrazino-3,4-dihydroxyphenylpropionic acid
• <span class="text-smallcaps">L</span>-α-Methyl-α-hydrazino-β-(3,4-dihydroxyphenyl)propionic acid
• <span class="text-smallcaps">L</span>-α-Methyl-β-(3,4-dihydroxyphenyl)-α-hydrazinopropionic acid
• <span class="text-smallcaps">L</span>-α-Methyldopahydrazine
• Benzenepropanoic acid, α-hydrazino-3,4-dihydroxy-α-methyl-, (S)-
• Benzenepropanoic acid, α-hydrazinyl-3,4-dihydroxy-α-methyl-, (αS)-
• Cabidopa
• Carbidopa
• HMD
• Hydrazino-α-methyldopa
• Hydrocinnamic acid, α-hydrazino-3,4-dihydroxy-α-methyl-, <span class="text-smallcaps">L</span>-
• Hydrocinnamic acid, α-hydrazino-3,4-dihydroxy-α-methyl-, L-
• L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
• L-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic acid
• L-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid
• L-α-Hydrazino-α-methyl-3,4-dihydroxyphenylpropionic acid
• L-α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic acid
• L-α-Methyl-α-hydrazino-3,4-dihydroxyphenylpropionic acid
• L-α-Methyl-α-hydrazino-β-(3,4-dihydroxyphenyl)propionic acid
• L-α-Methyl-β-(3,4-dihydroxyphenyl)-α-hydrazinopropionic acid
• L-α-Methyldopahydrazine
• Lodosin
• Lodosyn
• Mk 486
• N-Aminomethyldopa
• α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic acid
• α-Methyldopahydrazine
• Benzenepropanoic acid, α-hydrazino-3,4-dihydroxy-α-methyl-, (αS)-
• L-alpha-Methyldopahydrazine
• 3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid
• Tocris-0455
• 1-(Mesithylene-2-sulfonyl)-3-nitro-1,2,4-triazole
• L-alpha-Methyl-alpha-hydrazino-beta-(3,4-dihydroxyphenylpropionic acid
• Carbidopum [INN-Latin]
• alpha-Hydrazino-alpha-methyl-beta-(3,4-dihydroxyphenyl)propionic acid
• CCRIS 5093
• 3-(3,4-DIHYDROXY-PHENYL)-2-HYDRAZINO-2-METHYL-PROPIONIC ACID
• (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid hydrate (1:1)
• (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid
• SMR000058235
• NCGC00024596-01
• (-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid
• alpha-hydrazino-3,4-dihydroxy-alpha-methyl-(S )-
• Carbidopa anhydrous
• Benzenepropanoic acid
• alpha-Methyldopahydrazine
• L-alpha-Methyl-beta-(3,4-dihydroxyphenyl)-alpha-hydrazinopropionic aci d
• alpha-HYDRAZINO-3,4-DIHYDROXY-alpha-METHYL-L-KINSON
• Hadrazino-alpha-methyldopa
• MLS000069628
• Carbidopa [USAN:BAN:INN:JAN]

3,3,3-trideuterio-2-[dideuterio-(3,4-dihydroxyphenyl)methyl]-2-hydrazinylpropanoic acid

CAS: 28860-95-9

• Fórmula: C₁₀H₁₄N₂O₄
• Pureza: 97%
• Cor e Forma: Solid
• Peso molecular: 226.2292

(S)-3-(3,4-Dihydroxyphenyl)-2-Hydrazinyl-2-Methylpropanoic Acid

CAS: 28860-95-9

• Pureza: 97%
• Peso molecular: 226.23g/mol

Carbidopa

CAS: 28860-95-9

• Pureza: 98%
• Peso molecular: 226.23g/mol

Carbidopa

CAS: 28860-95-9

• Fórmula: C₁₀H₁₄N₂O₄
• Cor e Forma: White To Off-White Solid
• Peso molecular: 226.23

Carbidopa Monohydrate

CAS: 28860-95-938821-49-7

• Fórmula: C₁₀H₁₄N₂O₄·H₂O
• Pureza: >98.0%(T)(HPLC)
• Cor e Forma: White to Light yellow powder to crystaline
• Peso molecular: 244.25

Carbidopa

CAS: 28860-95-9

Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM).

• Fórmula: C₁₀H₁₄N₂O₄
• Pureza: 98.01% - ≥98%
• Cor e Forma: Solid
• Peso molecular: 226.23

(S)-(-)-Carbidopa

CAS: 28860-95-9

Stability Unstable in Solution Applications (S)-(-)-Carbidopa is a peripheral decarboxylase inhibitor that is commonly used …

• Fórmula: C₁₀H₁₄N₂O₄
• Cor e Forma: Neat
• Peso molecular: 226.23

(2S)-3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid

CAS: 28860-95-9

Please enquire for more information about (2S)-3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid including the price, delivery time and more …

• Fórmula: C₁₀H₁₄N₂O₄
• Pureza: Min. 95%
• Peso molecular: 226.23 g/mol