CAS 28920-43-6

Cloroformato de 9-fluorenilmetilo

Descrição:

Cloroformato de 9-fluorenilmetilo, com o número CAS 28920-43-6, é um composto orgânico comumente utilizado como reagente na síntese orgânica, particularmente no campo da química de peptídeos e aminoácidos. Apresenta um grupo fluorenilmetila, que aumenta sua reatividade e solubilidade em solventes orgânicos. O composto é caracterizado por seu grupo funcional cloroformato, conhecido por sua capacidade de formar carbamatos ao reagir com aminas. Essa propriedade o torna valioso para proteger grupos amino durante processos de síntese em várias etapas. Cloroformato de 9-fluorenilmetilo é tipicamente um líquido incolor a amarelo pálido, e é sensível à umidade e ao ar, exigindo manuseio e armazenamento cuidadosos em condições inertes. Sua reatividade pode ser atribuída à natureza eletrofílica do carbono carbonílico no grupo cloroformato, permitindo que participe de reações de substituição nucleofílica. No geral, este composto é uma ferramenta importante na química orgânica sintética, particularmente para a proteção e ativação de grupos funcionais.

Fórmula: C₁₅H₁₁ClO₂

InChI: InChI=1S/C15H11ClO2/c16-15(17)18-9-14-12-7-3-1-5-10(12)11-6-2-4-8-13(11)14/h1-8,14H,9H2

Chave InChI: InChIKey=IRXSLJNXXZKURP-UHFFFAOYSA-N

SMILES: C(OC(Cl)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinónimos:

• (9H-Fluoren-9-ylmethoxy)carbonyl chloride
• 9-Fluorenylmethoxycarbonyl
• 9-Fluorenylmethoxycarbonyl chloride
• 9-Fluorenylmethyl chlorocarbonate
• 9-Fluorenylmethyloxycarbonylchloride
• 9H-Fluoren-9-ylmethylchlorformiat
• 9H-fluoren-9-ylmethyl carbonochloridate
• 9H-fluoren-9-ylmethyl chloroformate
• AminoTag
• Carbonic acid, monoanhydride with carbonochloridic acid, 9H-fluoren-9-ylmethyl ester
• Carbonochloridic acid, 9H-fluoren-9-ylmethyl ester
• Chloroformate, (9-Fluorenylmethyl)
• Chloroformiate de 9H-fluoren-9-ylmethyle
• Chloroformic acid 9-fluorenylmethyl ester
• FMOC-chloride
• Fluorene-9-methanol, chloroformate
• Fluorenylmethyl chloroformate
• Fmoc-Cl
• FmocCl
• Formic acid, chloro-, fluoren-9-ylmethyl ester
• chloroformiate de 9H-fluorene-9-ylmethyle
• cloroformiato de 9H-fluoren-9-ilmetilo

9-Fluorenylmethyl Chloroformate [N-Protecting Agent for Peptides Research]

CAS: 28920-43-6

Fórmula: C₁₅H₁₁ClO₂

Pureza: >97.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystaline

Peso molecular: 258.70

Ref: 3B-F0197

9-Fluorenylmethyl chloroformate, 98+%

CAS: 28920-43-6

Base sensitive amino protecting group for solid-phase peptide synthesis9-Fluorenylmethyl chloroformate is used in capillary electrophoresis. It acts as a reagent in the precolumn derivatization of amines for HPLC and fluorescent detection. Further, it is used for derivatizing amino acids for HPLC an

Fórmula: C₁₅H₁₁ClO₂

Pureza: 98+%

Cor e Forma: White or cream or pale yellow, Powder

Peso molecular: 258.70

Ref: 02-A11683

Fmoc-Cl

CAS: 28920-43-6

Reagent for the introduction of the Fmoc-amino-protecting group, which is stable towards acids and catalytic hydrogenation but is readily cleaved under mildly basic non-hydrolytic conditions. The use of this reagent in the protection of hydroxy groups and amino groups in nucleotides has been reported as well. Fmoc-chloride is often used for pre-column derivatization of amines and amino acids in analytical HPLC.

Fórmula: C₁₅H₁₁ClO₂

Pureza: 98.9%

Cor e Forma: Whitish

Peso molecular: 258.7

Ref: 01-4004776

9H-Fluoren-9-ylmethyl chloroformate

CAS: 28920-43-6

Fórmula: C₁₅H₁₁ClO₂

Pureza: 96%

Cor e Forma: Solid

Peso molecular: 258.6996

Ref: IN-DA002X2Y

Fmoc chloride

CAS: 28920-43-6

Fórmula: C₁₅H₁₁ClO₂

Pureza: ≥ 97.0%

Cor e Forma: White to off-white or pale yellow-orange crystalline powder

Peso molecular: 258.70

Ref: 7W-GE3236

(9H-Fluoren-9-yl)methyl chloroformate

CAS: 28920-43-6

(9H-Fluoren-9-yl)methyl chloroformate

Fórmula: C₁₅H₁₁ClO₂

Pureza: ≥95%

Cor e Forma: white to light yellow to orange crystal or chunks or powder

Peso molecular: 258.69964g/mol

Ref: 54-OR13210

Fmoc-Chloride

CAS: 28920-43-6

Fórmula: C₁₅H₁₁ClO₂

Pureza: 97.0%

Cor e Forma: Solid

Peso molecular: 258.7

Ref: 10-F022072

(9-Fluorenylmethyl) Chloroformate

CAS: 28920-43-6

Fórmula: C₁₅H₁₁ClO₂

Peso molecular: 258.70

Ref: 4Z-C-334007

9-Fluorenylmethyl Chlorocarbonate

CAS: 28920-43-6

Stability Moisture Sensitive
Applications 9-Fluorenylmethyl Chlorocarbonate is an N-Protecting agent for peptides research and was used for the pre-column derivatization of the biogenic amines (BAs) cadaverine (Cad), histamine (Him), octopamine (Ocp), phenylethylamine (Pea), putrescine (Put), spermidine (Spd), spermine (Spm), tyramine (Tym).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rebane, R., et al.: J. Chromatograph. Anal. Technol. Biomed. Life. Sci., 904, 99 (2012); Brueckner, H., et al.: Amino. Acids., 42, 877 (2012);

Fórmula: C₁₅H₁₁ClO₂

Cor e Forma: Light Yellow

Peso molecular: 258.70

Ref: TR-F472450

Fmoc-Cl

CAS: 28920-43-6

Fmoc-Cl is a fluorescent derivative that can be used as an analytical method for amino acids in human serum. This reagent is synthesized from chloroformate and derivatization of the amino acid with polymyxin B. Fmoc-Cl reacts with amino acids, producing a fluorescent molecule. The reaction solution can be applied to human serum to determine the concentration of various types of amino acids in the sample. The main matrix effect comes from the presence of human serum proteins, which have been shown to interfere with the measurement of some amino acid concentrations. Fmoc-Cl has also been studied as a potential therapeutic agent for autoimmune diseases, such as multiple sclerosis, lupus erythematosus, and rheumatoid arthritis. It has been shown that Fmoc-Cl inhibits complex enzymes and can reduce levels of certain inflammatory markers in animal models.

Fórmula: C₁₅H₁₁ClO₂

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 258.7 g/mol

Ref: 3D-FF07779

9-Fluorenylmethyl Chloroformate (FMOC Chloride, FMOC-Cl) extrapure, 99%

CAS: 28920-43-6

Fórmula: C₁₅H₁₁ClO₂

Pureza: min. 99%

Cor e Forma: White to off-white, Crystalline powder

Peso molecular: 258.70

Ref: SR-54083